2008
Cerebrovascular Disease Risk in Older Head and Neck Cancer Patients After Radiotherapy
Smith GL, Smith BD, Buchholz TA, Giordano SH, Garden AS, Woodward WA, Krumholz HM, Weber RS, Ang K, Rosenthal DI. Cerebrovascular Disease Risk in Older Head and Neck Cancer Patients After Radiotherapy. Journal Of Clinical Oncology 2008, 26: 5119-5125. PMID: 18725647, PMCID: PMC4879715, DOI: 10.1200/jco.2008.16.6546.Peer-Reviewed Original ResearchConceptsCerebrovascular disease riskNeck cancer patientsDisease riskCerebrovascular eventsCerebrovascular riskCardiac riskCancer patientsNeck cancerTreatment groupsTen-year incidenceProportional hazards regressionDefinitive radiotherapyPostoperative radiotherapyCardiac eventsOlder patientsCerebrovascular diseaseHazards regressionNonmetastatic headMean ageVascular diseaseBaseline riskPatientsSurgeryRadiotherapyControl diagnosis
2003
A Critical Evaluation of Critical Pathways in Head and Neck Cancer
Yueh B, Weaver EM, Bradley EH, Krumholz HM, Heagerty P, Conley A, Sasaki CT. A Critical Evaluation of Critical Pathways in Head and Neck Cancer. JAMA Otolaryngology - Head & Neck Surgery 2003, 129: 89-95. PMID: 12525201, DOI: 10.1001/archotol.129.1.89.Peer-Reviewed Original ResearchConceptsNeck cancerCritical pathwaysLaryngectomy patientsManagement of headLow-volume proceduresLinear spline regression modelsPathway adoptionObservational cohortPathway patientsContemporary cohortHistorical cohortPathway implementationMedical CenterSpline regression modelsConfounding variablesLaryngectomyPatientsUtilization trendsCohortPrior reportsIndependent impactLOSSignificant differencesCancer