2013
Urinary Biomarkers of AKI and Mortality 3 Years after Cardiac Surgery
Coca SG, Garg AX, Thiessen-Philbrook H, Koyner JL, Patel UD, Krumholz HM, Shlipak MG, Parikh CR. Urinary Biomarkers of AKI and Mortality 3 Years after Cardiac Surgery. Journal Of The American Society Of Nephrology 2013, 25: 1063-1071. PMID: 24357673, PMCID: PMC4005309, DOI: 10.1681/asn.2013070742.Peer-Reviewed Original ResearchConceptsKidney injury molecule-1Long-term mortalityIL-18Urinary biomarkersClinical AKICardiac surgeryHighest tertileUrinary neutrophil gelatinase-associated lipocalinProspective long-term followNeutrophil gelatinase-associated lipocalinContinuous net reclassification improvementInjury molecule-1Kidney injury biomarkersPostoperative day 1Gelatinase-associated lipocalinImmediate postoperative periodAdditional prognostic informationLong-term followNet reclassification improvementMortality 3 yearsLiver fatty acidAKI cohortCause mortalityHospital outcomesKidney injury
1994
Lack of Association Between Cholesterol and Coronary Heart Disease Mortality and Morbidity and All-Cause Mortality in Persons Older Than 70 Years
Krumholz HM, Seeman TE, Merrill SS, Mendes de Leon CF, Vaccarino V, Silverman DI, Tsukahara R, Ostfeld AM, Berkman LF. Lack of Association Between Cholesterol and Coronary Heart Disease Mortality and Morbidity and All-Cause Mortality in Persons Older Than 70 Years. JAMA 1994, 272: 1335-1340. PMID: 7772105, DOI: 10.1001/jama.1994.03520170045034.Peer-Reviewed Original ResearchConceptsCoronary heart disease mortalityHeart disease mortalityTotal serum cholesterolSerum cholesterol levelsRisk factor-adjusted odds ratioFactor-adjusted odds ratiosTotal serum cholesterol levelsCause mortalityCoronary heart diseaseHDL-C levelsUnstable anginaHighest tertileCholesterol levelsSerum cholesterolMyocardial infarctionDisease mortalityLow HDLLowest tertileHeart diseaseRisk factorsOdds ratioElevated total serum cholesterol levelsHigher total serum cholesterolCommunity-based cohort studyHigh-density lipoprotein cholesterol