2020
Attribution of Adverse Events Following Coronary Stent Placement Identified Using Administrative Claims Data
Dhruva SS, Parzynski CS, Gamble GM, Curtis JP, Desai NR, Yeh RW, Masoudi FA, Kuntz R, Shaw RE, Marinac‐Dabic D, Sedrakyan A, Normand S, Krumholz HM, Ross JS. Attribution of Adverse Events Following Coronary Stent Placement Identified Using Administrative Claims Data. Journal Of The American Heart Association 2020, 9: e013606. PMID: 32063087, PMCID: PMC7070203, DOI: 10.1161/jaha.119.013606.Peer-Reviewed Original ResearchMeSH KeywordsAdministrative Claims, HealthcareAgedAged, 80 and overCoronary RestenosisCoronary ThrombosisDatabases, FactualDrug-Eluting StentsFemaleHumansMaleMedicareMyocardial InfarctionPercutaneous Coronary InterventionProduct Surveillance, PostmarketingRegistriesRetreatmentRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsIndex percutaneous coronary interventionPercutaneous coronary interventionSame coronary arteryDrug-eluting stentsNCDR CathPCI RegistrySubsequent percutaneous coronary interventionAcute myocardial infarctionCoronary arteryClaims dataCathPCI RegistryAdverse eventsIndex procedureMyocardial infarctionRepeat percutaneous coronary interventionReal-world registry dataTarget vessel revascularizationCoronary stent placementAdministrative claims dataLong-term safetyLongitudinal claims dataPotential safety eventsVessel revascularizationCoronary interventionDES placementStent thrombosis
2019
Development and Validation of a Model for Predicting the Risk of Acute Kidney Injury Associated With Contrast Volume Levels During Percutaneous Coronary Intervention
Huang C, Li SX, Mahajan S, Testani JM, Wilson FP, Mena CI, Masoudi FA, Rumsfeld JS, Spertus JA, Mortazavi BJ, Krumholz HM. Development and Validation of a Model for Predicting the Risk of Acute Kidney Injury Associated With Contrast Volume Levels During Percutaneous Coronary Intervention. JAMA Network Open 2019, 2: e1916021. PMID: 31755952, PMCID: PMC6902830, DOI: 10.1001/jamanetworkopen.2019.16021.Peer-Reviewed Original ResearchConceptsCreatinine level increaseAcute kidney injuryPercutaneous coronary interventionContrast volumeAKI riskKidney injuryCoronary interventionBaseline riskCardiology National Cardiovascular Data Registry's CathPCI RegistryNational Cardiovascular Data Registry CathPCI RegistryRisk of AKIAcute Kidney Injury AssociatedDifferent baseline risksPCI safetyCathPCI RegistryInjury AssociatedMean ageDerivation setPreprocedural riskMAIN OUTCOMEAmerican CollegePrognostic studiesUS hospitalsCalibration slopeValidation setMyocardial infarction with non-obstructive coronary arteries as compared with myocardial infarction and obstructive coronary disease: outcomes in a Medicare population
Dreyer RP, Tavella R, Curtis JP, Wang Y, Pauspathy S, Messenger J, Rumsfeld JS, Maddox TM, Krumholz HM, Spertus JA, Beltrame JF. Myocardial infarction with non-obstructive coronary arteries as compared with myocardial infarction and obstructive coronary disease: outcomes in a Medicare population. European Heart Journal 2019, 41: 870-878. PMID: 31222249, PMCID: PMC7778433, DOI: 10.1093/eurheartj/ehz403.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsAcute myocardial infarctionHeart failureMyocardial infarctionCoronary angiographyComponents of MACENational Cardiovascular Data Registry CathPCI RegistryNon-obstructive coronary arteriesObstructive coronary artery diseaseAdverse cardiac eventsMajor adverse eventsObservational cohort studyObstructive coronary diseasePrognosis of patientsCoronary artery diseaseMACE componentsMINOCA patientsAdjusted riskCause mortalityPrimary endpointSecondary endpointsAdverse eventsCardiac eventsCathPCI RegistryCohort study
2017
Hospital Performance on Percutaneous Coronary Intervention Process and Outcomes Measures
Chui PW, Parzynski CS, Nallamothu BK, Masoudi FA, Krumholz HM, Curtis JP. Hospital Performance on Percutaneous Coronary Intervention Process and Outcomes Measures. Journal Of The American Heart Association 2017, 6: e004276. PMID: 28446493, PMCID: PMC5524055, DOI: 10.1161/jaha.116.004276.Peer-Reviewed Original ResearchMeSH KeywordsCardiac RehabilitationCoronary DiseaseCross-Sectional StudiesHealthcare DisparitiesHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMedicarePatient DischargePatient ReadmissionPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsProcess Assessment, Health CareQuality ImprovementQuality Indicators, Health CareReferral and ConsultationRegistriesRisk FactorsTime FactorsTime-to-TreatmentTreatment OutcomeUnited StatesConceptsProcess measuresReadmission ratesOutcome measuresNational Cardiovascular Data Registry CathPCI RegistryHospital performancePercutaneous coronary interventionSpecific process measuresRisk-standardized mortalityPCI patientsCathPCI RegistryCoronary interventionHospital variationOutcome ratesHospital qualityPhysician ConsortiumMortalitySmall percentageWeak correlationAssociationIntervention processPatients
2015
Appropriate Use Criteria for Coronary Revascularization and Trends in Utilization, Patient Selection, and Appropriateness of Percutaneous Coronary Intervention
Desai NR, Bradley SM, Parzynski CS, Nallamothu BK, Chan PS, Spertus JA, Patel MR, Ader J, Soufer A, Krumholz HM, Curtis JP. Appropriate Use Criteria for Coronary Revascularization and Trends in Utilization, Patient Selection, and Appropriateness of Percutaneous Coronary Intervention. JAMA 2015, 314: 2045-2053. PMID: 26551163, PMCID: PMC5459470, DOI: 10.1001/jama.2015.13764.Peer-Reviewed Original ResearchConceptsNonacute percutaneous coronary interventionPercutaneous coronary interventionAppropriate use criteriaInappropriate percutaneous coronary interventionHospital-level variationCoronary revascularizationPatient selectionUse criteriaCoronary interventionStudy periodAppropriateness of PCINational Cardiovascular Data Registry CathPCI RegistryProportion of PCIsMultivessel coronary artery diseaseHigh-risk findingsCoronary artery diseaseAnnual PCI volumesCross-sectional analysisAngina severityAntianginal medicationsAcute indicationsCathPCI RegistryArtery diseasePCI volumePCI procedures
2014
Relation between door-to-balloon times and mortality after primary percutaneous coronary intervention over time: a retrospective study
Nallamothu BK, Normand SL, Wang Y, Hofer TP, Brush JE, Messenger JC, Bradley EH, Rumsfeld JS, Krumholz HM. Relation between door-to-balloon times and mortality after primary percutaneous coronary intervention over time: a retrospective study. The Lancet 2014, 385: 1114-1122. PMID: 25467573, PMCID: PMC4409657, DOI: 10.1016/s0140-6736(14)61932-2.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionD2B timePercutaneous coronary interventionPopulation of patientsHospital mortalityBalloon timeCoronary interventionRetrospective studyMortality riskNational Cardiovascular Data Registry CathPCI RegistryST-elevation myocardial infarction (STEMI) patientsProcedural factorsStudy periodMyocardial infarction patientsNumber of patientsShorter D2B timesPopulation levelSecular trendsAbsence of associationPrimary PCICathPCI RegistryElderly patientsBlood InstituteEntire cohortAverage door
2013
Age and sex differences in inhospital complication rates and mortality after percutaneous coronary intervention procedures: Evidence from the NCDR®
Lichtman JH, Wang Y, Jones SB, Leifheit-Limson EC, Shaw LJ, Vaccarino V, Rumsfeld JS, Krumholz HM, Curtis JP. Age and sex differences in inhospital complication rates and mortality after percutaneous coronary intervention procedures: Evidence from the NCDR®. American Heart Journal 2013, 167: 376-383. PMID: 24576523, DOI: 10.1016/j.ahj.2013.11.001.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionComplication rateOlder womenPCI typeYoung womenInhospital mortalityMortality riskAge groupsElective percutaneous coronary interventionPercutaneous coronary intervention (PCI) proceduresInhospital complication rateRate of complicationsHigh complication rateRisk-adjusted analysisRisk-adjusted mortalityCoronary intervention proceduresUnadjusted complication rateSex-based differencesPCI patientsCathPCI RegistryCoronary interventionYounger patientsClinical factorsHospital admissionMore complicationsDeterminants of fluoroscopy time for invasive coronary angiography and percutaneous coronary intervention: Insights from the NCDR®
Fazel R, Curtis J, Wang Y, Einstein AJ, Smith‐Bindman R, Tsai TT, Chen J, Shah ND, Krumholz HM, Nallamothu BK. Determinants of fluoroscopy time for invasive coronary angiography and percutaneous coronary intervention: Insights from the NCDR®. Catheterization And Cardiovascular Interventions 2013, 82: 1091-1105. PMID: 23703793, DOI: 10.1002/ccd.24996.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionInvasive coronary angiographyHospital-level factorsFluoroscopy timePrior CABGCoronary interventionPrior coronary artery bypassRadiation exposureCoronary artery bypassNumerous clinical scenariosArtery bypassCathPCI RegistryPatient characteristicsCoronary angiographyPCI proceduresModifiable determinantsPatientsClinical scenariosModifiable sourceProcedure complexityCABGMinutesInterventionExposureWide variation
2012
Development of 2 Registry-Based Risk Models Suitable for Characterizing Hospital Performance on 30-Day All-Cause Mortality Rates Among Patients Undergoing Percutaneous Coronary Intervention
Curtis JP, Geary LL, Wang Y, Chen J, Drye EE, Grosso LM, Spertus JA, Rumsfeld JS, Weintraub WS, Masoudi FA, Brindis RG, Krumholz HM. Development of 2 Registry-Based Risk Models Suitable for Characterizing Hospital Performance on 30-Day All-Cause Mortality Rates Among Patients Undergoing Percutaneous Coronary Intervention. Circulation Cardiovascular Quality And Outcomes 2012, 5: 628-637. PMID: 22949491, DOI: 10.1161/circoutcomes.111.964569.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overAngina PectorisChi-Square DistributionComorbidityFemaleHeart DiseasesHospital MortalityHospitalsHumansLogistic ModelsMaleMyocardial InfarctionOdds RatioOutcome and Process Assessment, Health CarePercutaneous Coronary InterventionQuality Indicators, Health CareRegistriesRisk AssessmentRisk FactorsShock, CardiogenicTime FactorsTreatment OutcomeUnited StatesConceptsST-segment elevation myocardial infarctionPercutaneous coronary interventionRisk-standardized mortality ratesElevation myocardial infarctionPatient mortality ratesMyocardial infarctionMortality rateCardiogenic shockCoronary interventionDerivation cohortHospital risk-standardized mortality ratesCause mortality ratesAdministrative claims dataQuality of careHierarchical logistic regression modelsNational Quality ForumLogistic regression modelsObserved mortality rateCathPCI RegistryNational HospitalClaims dataInfarctionPatientsQuality ForumFinal model
2011
Use and Effectiveness of Intra-Aortic Balloon Pumps Among Patients Undergoing High Risk Percutaneous Coronary Intervention
Curtis JP, Rathore SS, Wang Y, Chen J, Nallamothu BK, Krumholz HM. Use and Effectiveness of Intra-Aortic Balloon Pumps Among Patients Undergoing High Risk Percutaneous Coronary Intervention. Circulation Cardiovascular Quality And Outcomes 2011, 5: 21-30. PMID: 22147887, PMCID: PMC3801197, DOI: 10.1161/circoutcomes.110.960385.Peer-Reviewed Original ResearchConceptsHigh-risk percutaneous coronary interventionIntra-aortic balloon pumpPercutaneous coronary interventionHospital quartilesHospital mortalityIABP useCoronary interventionBalloon pumpHospital characteristicsST-segment elevation myocardial infarctionDepressed left ventricular functionHigh-risk PCI patientsSegment elevation myocardial infarctionElevation myocardial infarctionLeft ventricular functionHierarchical logistic regression modelsLogistic regression modelsIABP usageCardiogenic shockPCI patientsCathPCI RegistryHemodynamic supportVentricular functionHospital variationMultivariable analysis
2009
National Efforts to Improve Door-to-Balloon Time Results From the Door-to-Balloon Alliance
Bradley EH, Nallamothu BK, Herrin J, Ting HH, Stern AF, Nembhard IM, Yuan CT, Green JC, Kline-Rogers E, Wang Y, Curtis JP, Webster TR, Masoudi FA, Fonarow GC, Brush JE, Krumholz HM. National Efforts to Improve Door-to-Balloon Time Results From the Door-to-Balloon Alliance. Journal Of The American College Of Cardiology 2009, 54: 2423-2429. PMID: 20082933, DOI: 10.1016/j.jacc.2009.11.003.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionD2B AllianceBalloon (D2B) AllianceHospital presentationD2B timeNational Cardiovascular Data Registry CathPCI RegistryPrimary percutaneous coronary interventionElevation myocardial infarctionPercutaneous coronary interventionLikelihood of patientsCathPCI RegistryCoronary interventionBalloon timeMyocardial infarctionAmerican CollegePatientsHospitalLongitudinal studyNational Quality CampaignOne-halfPresentationMinNational effortsInfarctionRegistry