2021
Evaluation of Internet-Based Crowdsourced Fundraising to Cover Health Care Costs in the United States
Angraal S, Zachariah AG, Raaisa R, Khera R, Rao P, Krumholz HM, Spertus JA. Evaluation of Internet-Based Crowdsourced Fundraising to Cover Health Care Costs in the United States. JAMA Network Open 2021, 4: e2033157. PMID: 33427882, PMCID: PMC7801937, DOI: 10.1001/jamanetworkopen.2020.33157.Peer-Reviewed Original Research
2018
Prediction of ICU Readmissions Using Data at Patient Discharge
Pakbin A, Rafi P, Hurley N, Schulz W, Krumholz M, Mortazavi J. Prediction of ICU Readmissions Using Data at Patient Discharge. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2018, 00: 4932-4935. PMID: 30441449, DOI: 10.1109/embc.2018.8513181.Peer-Reviewed Original ResearchConceptsICU readmissionHigher health care costsSame hospital admissionElectronic health record dataPoor patient outcomesHealth record dataLong-term riskHealth care costsICU dischargeUnplanned readmissionHospital admissionPatient dischargePatient outcomesICU casesClinical careReadmissionCare costsRecord data
2015
An Administrative Claims Measure of Payments Made for Medicare Patients for a 30-Day Episode of Care for Acute Myocardial Infarction
Kim N, Bernheim SM, Ott LS, Han L, Spivack SB, Xu X, Volpe M, Liu A, Krumholz HM. An Administrative Claims Measure of Payments Made for Medicare Patients for a 30-Day Episode of Care for Acute Myocardial Infarction. Medical Care 2015, 53: 542-549. PMID: 25970575, DOI: 10.1097/mlr.0000000000000361.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionICD-9 codes 410Administrative Claims MeasurePatients 65 yearsDate of admissionClaims-based measuresIntraclass correlation coefficient scoreIntraclass correlation coefficientValue of careHigh-value careClinical variablesDischarge diagnosisMedicare patientsMedicare claimsClinical careAMI episodeAMI hospitalizationCare costsCode 410HospitalizationMedicaid ServicesHospitalClaims measuresCareOlder Women With Localized Breast Cancer: Costs And Survival Rates Increased Across Two Time Periods
Feinstein AJ, Long J, Soulos PR, Ma X, Herrin J, Frick KD, Chagpar AB, Krumholz HM, Yu JB, Ross JS, Gross CP. Older Women With Localized Breast Cancer: Costs And Survival Rates Increased Across Two Time Periods. Health Affairs 2015, 34: 592-600. PMID: 25847641, DOI: 10.1377/hlthaff.2014.1119.Peer-Reviewed Original ResearchConceptsStage II diseaseStage III diseaseCancer-related costsCancer careBreast cancerMedian costSurvival rateEnd Results Program-MedicareFive-year survivalCancer care costsBreast surgerySurvival outcomesImproved outcomesOlder womenRadiation therapyCare costsStage IIDiseaseStudy periodWomenCancerCareSignificant national attentionOutcomesPercent
2012
Appropriate And Inappropriate Imaging Rates For Prostate Cancer Go Hand In Hand By Region, As If Set By Thermostat
Makarov DV, Desai R, Yu JB, Sharma R, Abraham N, Albertsen PC, Krumholz HM, Penson DF, Gross CP. Appropriate And Inappropriate Imaging Rates For Prostate Cancer Go Hand In Hand By Region, As If Set By Thermostat. Health Affairs 2012, 31: 730-740. PMID: 22492890, DOI: 10.1377/hlthaff.2011.0336.Peer-Reviewed Original ResearchConceptsInappropriate imagingAppropriate imagingProstate cancerHigh-risk prostate cancerHigh rateHigh-risk patientsHealth care utilizationProstate cancer patientsCross-sectional studyOverall imaging rateHealth care costsLower ratesCare utilizationCancer patientsAppropriate treatmentAdvanced imagingCare costsPatientsHealth care organizationsCare organizationsCancerCost containmentImagingImaging rateRegional variation
2011
Generic Atorvastatin and Health Care Costs
Jackevicius CA, Chou MM, Ross JS, Shah ND, Krumholz HM. Generic Atorvastatin and Health Care Costs. New England Journal Of Medicine 2011, 366: 201-204. PMID: 22149736, PMCID: PMC3319770, DOI: 10.1056/nejmp1113112.Peer-Reviewed Original Research
2005
Enrollment of Older Persons in Cancer Trials After the Medicare Reimbursement Policy Change
Gross CP, Wong N, Dubin JA, Mayne ST, Krumholz HM. Enrollment of Older Persons in Cancer Trials After the Medicare Reimbursement Policy Change. JAMA Internal Medicine 2005, 165: 1514-1520. PMID: 16009867, DOI: 10.1001/archinte.165.13.1514.Peer-Reviewed Original ResearchConceptsOlder patientsCancer trialsReimbursement policy changesOlder personsPatients' sociodemographic characteristicsTrial exclusion criteriaMultivariate logistic regressionProstate cancer trialsProportion of participantsNational Cancer InstituteRoutine care costsSignificant changesClinical trialsPrimary study sampleExclusion criteriaTrial participantsCancer InstitutePatientsPrimary analysisCare costsMultivariate analysisSecondary analysisSociodemographic characteristicsLogistic regressionCancer types
2004
Cancer Trial Enrollment After State-Mandated Reimbursement
Gross CP, Murthy V, Li Y, Kaluzny AD, Krumholz HM. Cancer Trial Enrollment After State-Mandated Reimbursement. Journal Of The National Cancer Institute 2004, 96: 1063-1069. PMID: 15265967, DOI: 10.1093/jnci/djh193.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsClinical Trials, Phase II as TopicClinical Trials, Phase III as TopicColorectal NeoplasmsFemaleGovernment RegulationHumansIncidenceLogistic ModelsLongitudinal StudiesLung NeoplasmsMaleMulticenter Studies as TopicNational Institutes of Health (U.S.)NeoplasmsPatient SelectionPoisson DistributionProstatic NeoplasmsReimbursement MechanismsRetrospective StudiesState GovernmentUnited StatesConceptsCancer trial enrollmentTrial enrollment ratesTrial enrollmentMultivariable analysisTrial participationOdds ratioTrial participantsCoverage policiesCancer trial participantsCooperative group trialsClinical trial enrollmentEarly phase trialsRecruitment of patientsCancer trial participationMedical care costsPhase II trial participantsCancer patientsPhase trialsCancer research studiesGroup trialsCare costsPoisson regressionCancer typesReimbursement policiesPhase II
1999
Economics, health-related quality of life, and cost-effectiveness methods for the TACTICS (Treat Angina with Aggrastat® [tirofiban] and Determine Cost of Therapy with Invasive or Conservative Strategy)–TIMI 18 trial
Weintraub W, Culler S, Kosinski A, Becker E, Mahoney E, Burnette J, Spertus J, Feeny D, Cohen D, Krumholz H, Ellis S, Demopoulos L, Robertson D, Boccuzzi S, Barr E, Cannon C. Economics, health-related quality of life, and cost-effectiveness methods for the TACTICS (Treat Angina with Aggrastat® [tirofiban] and Determine Cost of Therapy with Invasive or Conservative Strategy)–TIMI 18 trial. The American Journal Of Cardiology 1999, 83: 317-322. PMID: 10072215, DOI: 10.1016/s0002-9149(98)00860-1.Peer-Reviewed Original ResearchConceptsQuality-adjusted life yearsHealth Utilities IndexLife yearsHealth-related qualityCost-effectiveness methodsNon-Q-wave myocardial infarctionUtility indexCost-effectiveness analysisDetermine CostImpact of invasiveEconomic formsUB92 formulationHealth care costsUnstable anginaRelative value scaleMedicare conversion factorMyocardial infarctionMedicare fee scheduleDepartmental costsEconomicsExpensive formFee scheduleTACTICS-TIMI 18Care costsOutcomes of patients
1995
In-hospital and one-year economic outcomes after coronary stenting or balloon angioplasty. Results from a randomized clinical trial. Stent Restenosis Study Investigators.
Cohen D, Krumholz H, Sukin C, Ho K, Siegrist R, Cleman M, Heuser R, Brinker J, Moses J, Savage M, Detre K, Leon M, Baim D. In-hospital and one-year economic outcomes after coronary stenting or balloon angioplasty. Results from a randomized clinical trial. Stent Restenosis Study Investigators. Circulation 1995, 92: 2480-7. PMID: 7586348, DOI: 10.1161/01.cir.92.9.2480.Peer-Reviewed Original ResearchConceptsMedical care costsInitial hospital costsCoronary stentingVascular complicationsConventional angioplastyBalloon angioplastyCare costsInitial hospitalizationInitial stentingHospital costsPalmaz-Schatz coronary stent implantationCatheterization laboratory costsElective coronary stentingPatient's initial hospitalizationSingle coronary lesionsSubsequent hospital visitsSubsequent revascularization proceduresSymptomatic coronary diseaseCoronary stent implantationConventional balloon angioplastyRandomized clinical trialsLength of stayDetailed resource utilizationAngiographic restenosisRepeat revascularization