2006
The Pre-Hospital Electrocardiogram and Time to Reperfusion in Patients With Acute Myocardial Infarction, 2000–2002 Findings From the National Registry of Myocardial Infarction-4
Curtis JP, Portnay EL, Wang Y, McNamara RL, Herrin J, Bradley EH, Magid DJ, Blaney ME, Canto JG, Krumholz HM. The Pre-Hospital Electrocardiogram and Time to Reperfusion in Patients With Acute Myocardial Infarction, 2000–2002 Findings From the National Registry of Myocardial Infarction-4. Journal Of The American College Of Cardiology 2006, 47: 1544-1552. PMID: 16630989, DOI: 10.1016/j.jacc.2005.10.077.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionPre-hospital electrocardiogramPrimary percutaneous coronary interventionMyocardial infarction 4Mean doorReperfusion timeHospital characteristicsNational registryTreatment of STEMILimited contemporary informationElevation myocardial infarctionPercutaneous coronary interventionBundle branch blockAcute reperfusionECG usePCI cohortReperfusion therapyBalloon timeCoronary interventionFibrinolytic therapyTherapy cohortMyocardial infarctionBranch blockNational guidelinesDrug time
2000
Thrombolytic therapy in older patients
Berger A, Radford M, Wang Y, Krumholz H. Thrombolytic therapy in older patients. Journal Of The American College Of Cardiology 2000, 36: 366-374. PMID: 10933344, DOI: 10.1016/s0735-1097(00)00723-3.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionPrimary angioplastyThrombolytic therapyOlder patientsBundle branch blockAcute reperfusionBranch blockST-segment elevationPatients age 65Population-based cohortReperfusion strategyReperfusion therapyHospital arrivalSurvival benefitSymptom onsetSegment elevationPhysician factorsST elevationMyocardial infarctionNational cohortAngioplastyBetter survivalMedicare beneficiariesLower mortalityPatients
1997
Thrombolytic Therapy for Eligible Elderly Patients With Acute Myocardial Infarction
Krumholz HM, Murillo JE, Chen J, Vaccarino V, Radford MJ, Ellerbeck EF, Wang Y. Thrombolytic Therapy for Eligible Elderly Patients With Acute Myocardial Infarction. JAMA 1997, 277: 1683-1688. PMID: 9169894, DOI: 10.1001/jama.1997.03540450039032.Peer-Reviewed Original ResearchConceptsST-segment elevationAcute myocardial infarctionThrombolytic therapyBundle branch blockMyocardial infarctionChest painElderly patientsMental statusBranch blockTotal ST-segment elevationEligible elderly patientsThrombolytic therapy useRetrospective cohort studyHours of symptomsOnset of symptomsPopulation-based sampleLack of treatmentDirect angioplastyEligible patientsAbsolute contraindicationBypass surgeryCohort studyMedical chartsTherapy useContiguous leads