2022
Percutaneous Left Atrial Appendage Occlusion in Comparison to Non‐Vitamin K Antagonist Oral Anticoagulant Among Patients With Atrial Fibrillation
Noseworthy PA, Van Houten HK, Krumholz HM, Kent DM, Abraham NS, Graff‐Radford J, Alkhouli M, Henk HJ, Shah ND, Gersh BJ, Friedman PA, Holmes DR, Yao X. Percutaneous Left Atrial Appendage Occlusion in Comparison to Non‐Vitamin K Antagonist Oral Anticoagulant Among Patients With Atrial Fibrillation. Journal Of The American Heart Association 2022, 11: e027001. PMID: 36172961, PMCID: PMC9673739, DOI: 10.1161/jaha.121.027001.Peer-Reviewed Original ResearchConceptsComposite end pointAtrial appendage occlusionOral anticoagulantsAtrial fibrillationLower riskMajor bleedingSystemic embolismIntracranial bleedingAppendage occlusionNon-Vitamin K Antagonist Oral AnticoagulantsIschemic stroke/systemic embolismK Antagonist Oral AnticoagulantsPrimary composite end pointPropensity score overlap weightingStroke/systemic embolismEnd pointHigh bleeding riskSignificant differencesAntithrombotic regimensBleeding riskCause mortalityBaseline characteristicsComposite outcomeIschemic strokeSecondary outcomes
2021
ASSOCIATION OF PERCUTANEOUS LEFT ATRIAL APPENDAGE OCCLUSION WITH STROKE, BLEEDING AND MORTALITY IN COMPARISON TO NOACS AMONG PATIENTS WITH AF
Yao X, Van Houten H, Krumholz H, Kent D, Shah N, Abraham N, Graff-Radford J, Alkhouli M, Henk H, Sangaralingham L, Gersh B, Friedman P, Holmes D, Noseworthy P. ASSOCIATION OF PERCUTANEOUS LEFT ATRIAL APPENDAGE OCCLUSION WITH STROKE, BLEEDING AND MORTALITY IN COMPARISON TO NOACS AMONG PATIENTS WITH AF. Journal Of The American College Of Cardiology 2021, 77: 286. DOI: 10.1016/s0735-1097(21)01645-4.Peer-Reviewed Original Research