1999
Biliary bile acids in primary biliary cirrhosis: Effect of ursodeoxycholic acid
Combes B, Carithers R, Maddrey W, Munoz S, Garcia‐Tsao G, Bonner G, Boyer J, Luketic V, Shiffman M, Peters M, White H, Zetterman R, Risser R, Rossi S, Hofmann A. Biliary bile acids in primary biliary cirrhosis: Effect of ursodeoxycholic acid. Hepatology 1999, 29: 1649-1654. PMID: 10347103, PMCID: PMC4004074, DOI: 10.1002/hep.510290618.Peer-Reviewed Original ResearchMeSH KeywordsBileBile Acids and SaltsChenodeoxycholic AcidCholic AcidChromatography, GasChromatography, High Pressure LiquidDeoxycholic AcidDouble-Blind MethodDrug Administration ScheduleFemaleHumansLithocholic AcidLiver Cirrhosis, BiliaryMaleMiddle AgedPlacebosRegression AnalysisReproducibility of ResultsTime FactorsUrsodeoxycholic AcidConceptsPrimary biliary cirrhosisBile acid compositionUrsodeoxycholic acidBile acidsBiliary cirrhosisSeverity of PBCSingle bedtime dosePlacebo-controlled trialBiliary bile acidsEndogenous bile acidsMajor bile acidsBedtime dosePlacebo medicationDuodenal bileHigh-pressure liquid chromatography methodPatientsNormal personsBileSignificant decreaseCirrhosisAcid compositionCDCATaurineLiquid chromatography methodYears
1995
Octreotide blunts postprandial splanchnic hyperemia in cirrhotic patients: A double-blind randomized echo-doppler study
Buonamico P, Sabba C, Garcia-Tsao G, Berardi E, Antonica G, Ferraioli G, Jensen J, Lerner E, Taylor K, Albano O, Groszmann R. Octreotide blunts postprandial splanchnic hyperemia in cirrhotic patients: A double-blind randomized echo-doppler study. Hepatology 1995, 21: 134-139. DOI: 10.1016/0270-9139(95)90420-4.Peer-Reviewed Original ResearchPortal vein cross-sectional areaPostprandial splanchnic hyperemiaSuperior mesenteric arteryCirrhotic patientsSMA-VSplanchnic hyperemiaSplanchnic hemodynamicsPlacebo administrationMeal ingestionPV-VFasted stateVein cross-sectional areaEcho-Doppler studyEffect of octreotideCrossover studyMesenteric arteryPulsatility indexLiquid mealPatientsSeparate daysCross-sectional areaSignificant decreaseIngestionHyperemiaSignificant increaseOctreotide blunts postprandial splanchnic hyperemia in cirrhotic patients: A double‐blind randomized echo‐doppler study
Buonamico P, Sabbá C, Garcia‐Tsao G, Berardi E, Antonica G, Ferraioli G, Jensen J, Lerner E, Taylor K, Albano O, Groszmann R. Octreotide blunts postprandial splanchnic hyperemia in cirrhotic patients: A double‐blind randomized echo‐doppler study. Hepatology 1995, 21: 134-139. PMID: 7806146, DOI: 10.1002/hep.1840210123.Peer-Reviewed Original ResearchConceptsPortal vein cross-sectional areaPostprandial splanchnic hyperemiaSuperior mesenteric arterySMA-VCirrhotic patientsSplanchnic hyperemiaSplanchnic hemodynamicsPlacebo administrationMeal ingestionPV-VFasted stateVein cross-sectional areaEcho-Doppler studyEffect of octreotideCrossover studyMesenteric arteryPulsatility indexLiquid mealPatientsSeparate daysCross-sectional areaSignificant decreaseIngestionHyperemiaSignificant increase