2008
Hepatic Vascular Malformations in Hereditary Hemorrhagic Telangiectasia
Khalid S, Garcia-Tsao G. Hepatic Vascular Malformations in Hereditary Hemorrhagic Telangiectasia. Seminars In Liver Disease 2008, 28: 247-258. PMID: 18814078, DOI: 10.1055/s-0028-1085093.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHereditary hemorrhagic telangiectasiaHepatic arteryVascular malformationsHepatic veinPortal veinHemorrhagic telangiectasiaHigh-output cardiac failureAbnormal vascular communicationAggressive medical therapyHepatic vascular malformationsPredominant clinical presentationCommon hepatic arteryNodular regenerative hyperplasiaIntensive medical treatmentFocal nodular hyperplasiaAutosomal dominant vascular disorderAbdominal anginaBiliary ischemiaLiver transplantationPortal hypertensionRegenerative hyperplasiaSymptomatic patientsCommon presentationMedical therapyCardiac failure
2006
Liver involvement in hereditary hemorrhagic telangiectasia: consensus recommendations
Buscarini E, Plauchu H, Tsao G, White RI, Sabbà C, Miller F, Saurin JC, Pelage JP, Lesca G, Marion MJ, Perna A, Faughnan ME. Liver involvement in hereditary hemorrhagic telangiectasia: consensus recommendations. Liver International 2006, 26: 1040-1046. PMID: 17032403, DOI: 10.1111/j.1478-3231.2006.01340.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHereditary hemorrhagic telangiectasiaLiver involvementHemorrhagic telangiectasiaIntensive medical therapyFormal consensus development processMinority of patientsFirst-line imagingFocal nodular hyperplasiaConsensus development processHHT populationLiver biopsyMedical therapyClinical managementNodular hyperplasiaConsensus statementConsensus recommendationsInvasive therapyDoppler USGeneral populationNominal group techniquePatientsTherapeutic issuesMedian scoreTherapyInvolvement
2000
Liver Disease in Patients with Hereditary Hemorrhagic Telangiectasia
Garcia-Tsao G, Korzenik J, Young L, Henderson K, Jain D, Byrd B, Pollak J, White R. Liver Disease in Patients with Hereditary Hemorrhagic Telangiectasia. New England Journal Of Medicine 2000, 343: 931-936. PMID: 11006369, DOI: 10.1056/nejm200009283431305.Peer-Reviewed Original ResearchConceptsHereditary hemorrhagic telangiectasiaHigh-output heart failureHemorrhagic telangiectasiaHeart failureMedian periodPortal hypertensionLiver involvementClinical findingsBiliary diseasePulmonary capillary wedge pressureElevated alkaline phosphatase levelsHepatic sinusoidal pressureSymptomatic liver involvementTypical clinical presentationAlkaline phosphatase levelsAutosomal dominant disorderHyperdynamic circulationAngiodysplastic lesionsCardiac indexLiver transplantationVariceal bleedingWedge pressureMedical therapyRendu-OslerClinical presentation