2023
Further decompensation in cirrhosis: Results of a large multicenter cohort study supporting Baveno VII statements
D’Amico G, Zipprich A, Villanueva C, Sordà J, Morillas R, Garcovich M, Retortillo M, Martinez J, Calès P, D’Amico M, Dollinger M, García-Guix M, Ballerga E, Tsochatzis E, Cirera I, Albillos A, Roquin G, Pasta L, Colomo A, Daruich J, Canete N, Boursier J, Dallio M, Gasbarrini A, Iacobellis A, Gobbo G, Merli M, Federico A, Baroni G, Pozzoni P, Addario L, Chessa L, Ridola L, Garcia-Tsao G. Further decompensation in cirrhosis: Results of a large multicenter cohort study supporting Baveno VII statements. Hepatology 2023, 79: 869-881. PMID: 37916970, DOI: 10.1097/hep.0000000000000652.Peer-Reviewed Original ResearchMulticenter cohort studyFurther decompensationLiver transplantFirst decompensationCumulative incidenceCohort studyLarge multicenter cohort studyCause-specific Cox modelsFive-year probabilityHazard ratioPrognostic weightPrognostic indicatorDecompensationCirrhosisCox modelPatientsAdvanced stageTransplantIncidenceMortalityDeathAscitesComplicationsMonths
2019
Gastroesophageal Variceal Bleeding Management
Zanetto A, Garcia-Tsao G. Gastroesophageal Variceal Bleeding Management. 2019, 39-66. DOI: 10.1007/978-3-030-24490-3_4.Peer-Reviewed Educational MaterialsGastroesophageal variceal bleedingVariceal bleedingLast decades survivalGeneral medical careMost recent seriesDecades survivalDecompensated patientsLiver transplantationBleeding managementDecompensated stageEffective treatmentClinical practiceMedical careMajor causeMultidisciplinary approachCirrhosisBleedingPatientsMortalityDeathRecent seriesHepatologistsTransplantationCare
2017
Chapter 36 Ascites
Garcia-Tsao G. Chapter 36 Ascites. 2017, 475-484. DOI: 10.1016/b978-0-12-804274-8.00036-9.Peer-Reviewed Educational MaterialsRefractory ascitesCommon decompensating eventNew-onset ascitesSodium-retaining systemsFirst-line therapyDevelopment of ascitesCause of deathPortal hypertensionRenal failureSodium retentionPathophysiological mechanismsOvert infectionAscitesPathogenic cascadeHigh mortalityVasodilatationEarly placementPatientsCirrhosisDeathHypertensionTherapyInfectionMortality
2016
Issues in Trial Design and Areas Needing Further Research
Abraldes J, Salerno F, Augustin S, Ripoll C, Reiberger T, Moreau R, Albillos A, Garcia-Tsao G. Issues in Trial Design and Areas Needing Further Research. 2016, 355-363. DOI: 10.1007/978-3-319-23018-4_35.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPrimary end pointVariceal bleedingEnd pointTrial designAppropriate primary end pointVariceal bleeding episodesComplications of cirrhosisNew therapeutic approachesBleeding episodesMultiple complicationsTherapeutic trialsCase mortalityTherapeutic approachesHigh riskLower riskPatientsClinical scenariosComplicationsBleedingPrevious trialsCirrhosisSecond complicationMortalityTrialsDeath
2014
Prognostic Factors in Compensated and Decompensated Cirrhosis
Ripoll C, Zipprich A, Garcia-Tsao G. Prognostic Factors in Compensated and Decompensated Cirrhosis. Current Hepatology Reports 2014, 13: 171-179. DOI: 10.1007/s11901-014-0234-6.Peer-Reviewed Original ResearchHepatic venous pressure gradientPortal hypertensionPredictive factorsSignificant portal hypertensionSpecific predictive factorsVenous pressure gradientSerum albumin levelAlternative non-invasive methodDecompensated diseaseMELD scoreClinical decompensationFurther decompensationAlbumin levelsPrognostic factorsNon-invasive methodCirrhosisInvasive proceduresDecompensationDeathHypertensionNumber of studiesImportant predictorChildren's scoresRecent studiesScores