1986
Dietary fish oil reduces progression of established renal disease in (NZB × NZW)F1 mice and delays renal disease in BXSB and MRL/1 strains
Robinson D, Prickett J, Makoul G, Steinberg A, Colvin R. Dietary fish oil reduces progression of established renal disease in (NZB × NZW)F1 mice and delays renal disease in BXSB and MRL/1 strains. Arthritis & Rheumatism 1986, 29: 539-546. PMID: 3707632, DOI: 10.1002/art.1780290412.Peer-Reviewed Original ResearchConceptsMRL-lpr/lpr miceRenal diseaseLpr miceNew Zealand black x New ZealandMedium-sized renal arteriesMice fed menhaden oilMenhaden oilDietary marine lipidsOvert renal diseaseSeverity of glomerulonephritisDietary fish oilBXSB/MpJRate of mortalityNecrotizing vasculitisHistologic severityGlomerular injuryNZB ×Renal arteryFatty acidsHistologic evidenceControl animalsMO dietLipid dietDiseaseMice
1985
Prostaglandin E2 inhibits the activation of cloned T cell hybridomas.
Makoul G, Robinson D, Bhalla A, Glimcher L. Prostaglandin E2 inhibits the activation of cloned T cell hybridomas. The Journal Of Immunology 1985, 134: 2645-50. PMID: 2857750, DOI: 10.4049/jimmunol.134.4.2645.Peer-Reviewed Original ResearchConceptsIL-2 secretionT cell hybridomasProstaglandin E2T cellsStimulator cellsCell hybridomasTA3 cellsCAMP levelsMarked inhibitionConcentrations of PGE2M prostaglandin E2IL-2 productionT cell activationDose-dependent mannerT hybridoma cellsMitogenic signalsImmunosuppressive effectsInterleukin-2M. PretreatmentSignificant elevationCell activationPhysiologic concentrationsMin of additionSimilar pretreatmentDcAMP