2019
Impact of early antiretroviral treatment on sexual behaviour: a randomised comparison
Lampe FC, Rodger AJ, Burman W, Grulich A, Friedland G, Sadr WE, Neaton J, Corbelli GM, Emery S, Molina JM, Orkin C, Gatell J, Gerstoft J, Ruxrungtham K, de Souza M, Phillips AN. Impact of early antiretroviral treatment on sexual behaviour: a randomised comparison. AIDS 2019, 33: 2337-2350. PMID: 31764099, PMCID: PMC6882545, DOI: 10.1097/qad.0000000000002359.Peer-Reviewed Original ResearchConceptsEarly antiretroviral treatmentHIV-serodifferent partnersAntiretroviral treatmentMonth 12Month 24CD4 cell countHIV-positive adultsSexual behaviorHIV infectiousnessImmediate armViral suppressionPrimary outcomeHigh prevalenceCondomless sexCell countMSMCells/Lower absolute levelsSexHeterosexual menTreatmentHeterosexualsArmAbsolute levelsPrevalence
2014
HIV Prevention Counseling Intervention Delivered During Routine Clinical Care Reduces HIV Risk Behavior in HIV-Infected South Africans Receiving Antiretroviral Therapy
Fisher JD, Cornman DH, Shuper PA, Christie S, Pillay S, Macdonald S, Ngcobo N, Amico KR, Lalloo U, Friedland G, Fisher WA. HIV Prevention Counseling Intervention Delivered During Routine Clinical Care Reduces HIV Risk Behavior in HIV-Infected South Africans Receiving Antiretroviral Therapy. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 67: 499-507. PMID: 25230288, PMCID: PMC4229426, DOI: 10.1097/qai.0000000000000348.Peer-Reviewed Original ResearchConceptsHIV risk behaviorsAntiretroviral therapyClinical care sitesLay counsellorsRisk behaviorsCare sitesRoutine clinical careStandard of careClinical care settingsCounseling interventionHIV careViral suppressionPrimary outcomeHIV statusRoutine careCare counselingCare participantsEffective behavioral interventionsHIV epidemicHIV preventionIntervention participantsCare settingsClinical careBrief interventionInfection incidence
2010
Preparing for highly active antiretroviral therapy rollout in rural South Africa: an assessment using the information, motivation, and behavioral skills model
Simon MD, Altice FL, Moll AP, Shange M, Friedland GH. Preparing for highly active antiretroviral therapy rollout in rural South Africa: an assessment using the information, motivation, and behavioral skills model. AIDS Care 2010, 22: 462-474. PMID: 20204909, DOI: 10.1080/09540120903220253.Peer-Reviewed Original ResearchConceptsActive antiretroviral therapy rolloutAntiretroviral therapy rolloutHIV/AIDSHAART rolloutHAART outcomesFolk remediesHIV treatment optimismMedication-taking behaviorOverall correct scoreBetter treatment outcomesResource-limited settingsBehavioral skills modelCommunity-based assessmentHAART initiationHIV optimismHIV testingHIV serostatusTreatment optimismTreatment outcomesSide effectsRural South AfricaCondom useHAARTTugela FerryYoung adults
2008
Episodic Antiretroviral Therapy Increases HIV Transmission Risk Compared With Continuous Therapy: Results of a Randomized Controlled Trial
Burman W, Grund B, Neuhaus J, Douglas J, Friedland G, Telzak E, Colebunders R, Paton N, Fisher M, Rietmeijer C. Episodic Antiretroviral Therapy Increases HIV Transmission Risk Compared With Continuous Therapy: Results of a Randomized Controlled Trial. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2008, 49: 142-150. PMID: 18769356, PMCID: PMC2749067, DOI: 10.1097/qai.0b013e318183a9ad.Peer-Reviewed Original ResearchConceptsHIV transmission riskHigh-risk behaviorsEpisodic antiretroviral therapyAntiretroviral therapyTransmission riskContinuous antiretroviral therapyHIV RNA levelsAntiretroviral Therapy studyProportion of participantsTherapy armContinuous therapyControlled TrialsRandomized armHIV transmissionMean ageNeedle sharingPatientsTherapyTherapy studiesStrategy of managementRNA levelsSexual activityRiskBaselineLaboratory testingAttitudes toward needle-sharing and HIV transmission risk behavior among HIV+ injection drug users in clinical care
Norton WE, Amico KR, Fisher WA, Copenhaver MM, Kozal MJ, Cornman DH, Friedland G, Fisher JD. Attitudes toward needle-sharing and HIV transmission risk behavior among HIV+ injection drug users in clinical care. AIDS Care 2008, 20: 462-469. PMID: 18449824, DOI: 10.1080/09540120701867081.Peer-Reviewed Original ResearchConceptsHIV-positive injection drug usersInjection drug usersRisk reduction interventionsClinical careDrug usersInjection drug use accountsHIV transmission risk behaviorsIncident HIV infectionTransmission risk behaviorsDrug-resistant HIVClinical care settingsSpread of HIVLogistic regression modelsAntiretroviral therapyHIV infectionHIV transmissionCare settingsRisk behaviorsClinical settingPast monthNegative attitudesSignificant correlatesHIVInterventionConsiderable proportion
2006
A population-based and longitudinal study of sexual behavior and multidrug-resistant HIV among patients in clinical care.
Kozal MJ, Amico KR, Chiarella J, Cornman D, Fisher W, Fisher J, Friedland G. A population-based and longitudinal study of sexual behavior and multidrug-resistant HIV among patients in clinical care. Medscape Journal Of Medicine 2006, 8: 72. PMID: 16926811, PMCID: PMC1785162.Peer-Reviewed Original ResearchConceptsSexual risk behaviorsUnprotected sexual eventsRisk behaviorsSelf-reported sexual risk behaviorDrug resistanceSerial cross-sectional analysisClasses of ARVsMultidrug-resistant HIVHIV-positive patientsAntiretroviral drug classesGenotypic drug resistanceHIV viral loadHIV sexual risk behaviorsHIV drug resistanceDrug-resistant HIVUnprotected sexual behaviorSame time pointsSexual eventsCross-sectional analysisGreat public healthVirologic resultsResistant HIVViral loadActive patientsARV resistance
2005
HIV Drug Resistance and HIV Transmission Risk Behaviors Among Active Injection Drug Users
Kozal MJ, Amico KR, Chiarella J, Cornman D, Fisher W, Fisher J, Friedland G. HIV Drug Resistance and HIV Transmission Risk Behaviors Among Active Injection Drug Users. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2005, 40: 106-109. PMID: 16123691, DOI: 10.1097/01.qai.0000159666.95455.d2.Peer-Reviewed Original ResearchConceptsInjection drug usersDrug-resistant HIVHIV drug resistanceResistant HIVDrug usersRisk behaviorsClinical careActive injection drug usersDrug resistanceHIV transmission risk behaviorsTransmission risk behaviorsInjection risk behaviorsRetrospective studyInjection drugsHIVPrevious monthCareSubstantial numberMultiple partnersDrugsSmall proportionPatientsProportionNeedleMonths
2003
Human Immunodeficiency Virus Infection Prevention: Strategies for Clinicians
Schreibman T, Friedland G. Human Immunodeficiency Virus Infection Prevention: Strategies for Clinicians. Clinical Infectious Diseases 2003, 36: 1171-1176. PMID: 12715313, DOI: 10.1086/374359.Peer-Reviewed Original ResearchConceptsHIV infectionClinical practiceHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionNew HIV infectionsClinical care sitesPrevention-related activitiesClinical care settingsIntegration of preventionEffective prevention programsPublic health modelFuture prevention activitiesSpecific prevention effortsHIV diseaseVirus infectionCare settingsCare sitesBehavioral counselingClinical careMedical interventionsPrevention programsInfectionPrevention effortsHealth modelPrevention activities