2012
Nosocomial Transmission of Extensively Drug-Resistant Tuberculosis in a Rural Hospital in South Africa
Gandhi NR, Weissman D, Moodley P, Ramathal M, Elson I, Kreiswirth BN, Mathema B, Shashkina E, Rothenberg R, Moll AP, Friedland G, Sturm AW, Shah NS. Nosocomial Transmission of Extensively Drug-Resistant Tuberculosis in a Rural Hospital in South Africa. The Journal Of Infectious Diseases 2012, 207: 9-17. PMID: 23166374, PMCID: PMC3523793, DOI: 10.1093/infdis/jis631.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntitubercular AgentsCluster AnalysisCross InfectionDrug Therapy, CombinationEthambutolExtensively Drug-Resistant TuberculosisFemaleGenotypeHIV InfectionsHospitals, RuralHumansIsoniazidMaleMutationMycobacterium tuberculosisPolymorphism, Restriction Fragment LengthPrevalencePyrazinamideRetrospective StudiesRifampinSequence Analysis, DNASouth AfricaConceptsDrug-resistant tuberculosisHuman immunodeficiency virusNosocomial transmissionEpidemiologic linkExtensively Drug-Resistant TuberculosisPoor infection controlSmear-positive tuberculosisMultidrug-resistant tuberculosisHigh HIV prevalencePoint-source outbreakGlobal public health threatPublic health threatResistance-determining regionXDR tuberculosisImmunodeficiency virusHIV prevalenceObservational studyInfection controlRural hospitalsPatientsTuberculosisTugela FerryFragment length polymorphism analysisHealth threatRestriction fragment length polymorphism analysis
2011
Spread of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa
Moodley P, Shah NS, Tayob N, Connolly C, Zetola N, Gandhi N, Friedland G, Sturm AW. Spread of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa. PLOS ONE 2011, 6: e17513. PMID: 21655324, PMCID: PMC3104985, DOI: 10.1371/journal.pone.0017513.Peer-Reviewed Original ResearchConceptsMDR-TB casesDrug-resistant tuberculosisXDR-TB casesXDR-TBDrug susceptibility test resultsExtensively Drug-Resistant TuberculosisMDR tuberculosis casesMDR-TB patientsXDR-TB patientsCulture-confirmed casesProvincial referral hospitalCross-sectional studyKwaZulu-Natal ProvinceSource of infectionTB casesNumber of hospitalsReferral hospitalSputum cultureTuberculosis casesScotland hospitalsPatientsHealthcare districtsHospitalClinical diagnosisLaboratory databaseIncreasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa - Volume 17, Number 3—March 2011 - Emerging Infectious Diseases journal - CDC
Shah NS, Richardson J, Moodley P, Moodley S, Babaria P, Ramtahal M, Heysell SK, Li X, Moll AP, Friedland G, Sturm AW, Gandhi NR. Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa - Volume 17, Number 3—March 2011 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2011, 17: 510-513. PMID: 21392446, PMCID: PMC3166021, DOI: 10.3201/eid1703.101363.Peer-Reviewed Original ResearchConceptsExtensively Drug-Resistant TuberculosisTuberculosis drug susceptibility testingDrug-resistant Mycobacterium tuberculosisInfectious Diseases journal - CDCDrug-resistant TBDrug-resistant tuberculosisDrug susceptibility testingEffective treatmentAvailable drugsDrug resistanceSusceptibility testingMycobacterium tuberculosisTuberculosisDrugsPatients