Role of renalase in the regulation of blood pressure and the renal dopamine system
Desir GV. Role of renalase in the regulation of blood pressure and the renal dopamine system. Current Opinion In Nephrology & Hypertension 2011, 20: 31-36. PMID: 21099685, DOI: 10.1097/mnh.0b013e3283412721.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseDahl salt-sensitive ratsRenal dopamine systemSalt-sensitive ratsRenalase deficiencyBlood pressureKidney diseaseRenalase levelsResistant hypertensionRecombinant renalaseDopamine systemProximal tubular sodium transportStable coronary artery diseaseComparable blood pressurePlasma renalase levelsRole of renalaseMechanisms of hypertensionNormal renal functionTubular sodium transportCoronary artery diseaseElevation of plasmaPotent antihypertensive agentSevere cardiac hypertrophyKnockout mouse modelRenalase expression