2016
Deep‐targeted exon sequencing reveals renal polymorphisms associate with postexercise hypotension among African Americans
Pescatello LS, Schifano ED, Ash GI, Panza GA, Lamberti L, Chen M, Deshpande V, Zaleski A, Farinatti P, Taylor BA, Thompson PD. Deep‐targeted exon sequencing reveals renal polymorphisms associate with postexercise hypotension among African Americans. Physiological Reports 2016, 4: e12992. PMID: 27940662, PMCID: PMC5064144, DOI: 10.14814/phy2.12992.Peer-Reviewed Original ResearchConceptsMultiple testing thresholdADD1 variantsAngiotensin type 1 receptorAmbulatory blood pressure responsesTesting thresholdBlood pressure responseExon sequencingAmbulatory BP monitorModerate-intensity exerciseType 1 receptorModerate-intensity cyclingPostexercise hypotensionRenal variantDiastolic BPAcute exerciseValidation cohortBP measurementsBP monitorIntensity exerciseVigorous intensityAdducin geneVariant genotypesAldosterone synthaseIntensity cyclingCYP11B2 variants
2013
The promises and challenges of the use of genomics in the prescription of exercise for hypertension: the 2013 update.
Ash GI, Eicher JD, Pescatello LS. The promises and challenges of the use of genomics in the prescription of exercise for hypertension: the 2013 update. Current Hypertension Reviews 2013, 9: 130-47. PMID: 23971695, DOI: 10.2174/15734021113099990010.Peer-Reviewed Original ResearchMeSH KeywordsBlood PressureExerciseExercise TherapyGenomicsHumansHypertensionPolymorphism, GeneticPrecision MedicineConceptsBP responseCardiovascular disease risk factorsMajor global public health problemGlobal public health problemControl of hypertensionDisease risk factorsEffectiveness of exercisePrescription of exercisePublic health problemExercise prescriptionRisk factorsHypertensionTherapeutic modalitiesAmerican CollegeConsiderable individual variabilityHealth problemsSports medicineAerobic activityModerate intensityNext-generation sequencingAssociation studiesSpecific genetic variantsSignificant proportionMost daysGenetic variants
2011
No Association between ACE Gene Variation and Endurance Athlete Status in Ethiopians
ASH GI, SCOTT RA, DEASON M, DAWSON TA, WOLDE B, BEKELE Z, TEKA S, PITSILADIS YP. No Association between ACE Gene Variation and Endurance Athlete Status in Ethiopians. Medicine & Science In Sports & Exercise 2011, 43: 590-597. PMID: 20798657, DOI: 10.1249/mss.0b013e3181f70bd6.Peer-Reviewed Original Research