2000
Clinical Characteristics as Predictors of Recurrent Alcohol‐related Seizures
Rathlev N, Ulrich A, Fish S, D'Onofrio G. Clinical Characteristics as Predictors of Recurrent Alcohol‐related Seizures. Academic Emergency Medicine 2000, 7: 886-891. PMID: 10958128, DOI: 10.1111/j.1553-2712.2000.tb02066.x.Peer-Reviewed Original ResearchConceptsAlcohol-related seizuresClinical characteristicsBlood pressureEthanol levelsRecurrent seizuresLower riskLower-risk clinical characteristicsPlacebo-treated patientsDiastolic blood pressureSubset of patientsSystolic blood pressureRetrospective secondary analysisDaily ethanol consumptionRecurrent alcoholPlacebo armRandomized trialsPrevious seizuresEmergency departmentEthanol abuseClinical dataDrug treatmentHeart rateEthanol consumptionSeizuresRespiratory rate
1994
The lack of efficacy of phenytoin in the prevention of recurrent alcohol-related seizures
Rathlev N, D'Onofrio G, Fish S, Harrison P, Bernstein E, Hossack R, Pickens L. The lack of efficacy of phenytoin in the prevention of recurrent alcohol-related seizures. Annals Of Emergency Medicine 1994, 23: 513-518. PMID: 8135426, DOI: 10.1016/s0196-0644(94)70070-2.Peer-Reviewed Original ResearchConceptsAlcohol-related seizuresSix-hour observation periodNormal saline placeboDouble-blind trialObservation periodConfidence intervalsLack of efficacyChronic alcohol abuseYears of ageChi 2 analysisPlacebo groupConsecutive adultsEligible subjectsPhenytoin groupSaline placeboGeneralized seizuresPhenytoin administrationSecond seizureEmergency departmentNormal salineRelative riskTeaching hospitalAlcohol abuseDrug AdministrationSeizures
1992
Sample size & selection criteria
Rathlev N, D'onofrio G, Fish S. Sample size & selection criteria. Annals Of Emergency Medicine 1992, 21: 344-345. PMID: 1536500, DOI: 10.1016/s0196-0644(05)80920-5.Peer-Reviewed Original Research