2003
Prognostic significance of ischemic electrocardiographic changes during adenosine infusion in patients with normal myocardial perfusion imaging
Abbott B, Afshar M, Berger A, Wackers F. Prognostic significance of ischemic electrocardiographic changes during adenosine infusion in patients with normal myocardial perfusion imaging. Journal Of Nuclear Cardiology 2003, 10: 9-16. PMID: 12569326, DOI: 10.1067/mnc.2002.127625.Peer-Reviewed Original ResearchConceptsNormal myocardial perfusion imagingAdenosine myocardial perfusion imagingST-segment depressionMyocardial perfusion imagingIschemic ECG changesCardiac eventsECG changesAdenosine infusionCardiac deathPrognostic significanceECG groupNormal myocardial perfusion imagesBaseline electrocardiographic abnormalitiesAdverse cardiac eventsIschemic electrocardiographic changesNonfatal myocardial infarctionSubsequent cardiac eventsFuture cardiac eventsNormal myocardial perfusionSex-matched groupPerfusion imagesECG evidenceElectrocardiographic abnormalitiesIndependent predictorsElectrocardiographic changes
1997
Relevance of Increased Lung Thallium Uptake on Stress Imaging in Patients With Unstable Angina and Non-Q Wave Myocardial Infarction: Results of the Thrombolysis in Myocardial Infarction (TIMI)-IIIB Study fn1fn1This study was supported in part by a research grant from Mallinckrodt Medical Inc., Saint Louis, Missouri.
Jain D, Thompson B, Wackers F, Zaret B, Investigators F. Relevance of Increased Lung Thallium Uptake on Stress Imaging in Patients With Unstable Angina and Non-Q Wave Myocardial Infarction: Results of the Thrombolysis in Myocardial Infarction (TIMI)-IIIB Study fn1fn1This study was supported in part by a research grant from Mallinckrodt Medical Inc., Saint Louis, Missouri. Journal Of The American College Of Cardiology 1997, 30: 421-429. PMID: 9247514, DOI: 10.1016/s0735-1097(97)00164-2.Peer-Reviewed Original ResearchConceptsLung/heart ratioAdverse cardiac eventsNon-Q-wave myocardial infarctionCoronary artery diseaseCardiac eventsPerfusion abnormalitiesMyocardial infarctionUnstable anginaArtery diseaseStress-induced left ventricular dysfunctionHigher cardiac event rateLeft ventricular ejection fractionAggressive interventional managementHigher revascularization rateLung thallium uptakeCardiac event rateTotal exercise timeFrequency of anginaLeft ventricular dysfunctionST-segment depressionLower exercise capacityVentricular ejection fractionPrevious myocardial infarctionMyocardial perfusion abnormalitiesNormal myocardial perfusion
1993
Detection and Significance of Myocardial Ischemia in Stable Patients After Recovery From an Acute Coronary Event
Moss A, Goldstein R, Hall W, Bigger J, Fleiss J, Greenberg H, Bodenheimer M, Krone R, Marcus F, Wackers F, Benhorin J, Brown M, Case R, Coromilas J, Dwyer E, Gillespie J, Gregory J, Kleiger R, Lichstein E, Parker J, Raubertas R, Stern S, Tzivoni D, Van Voorhees L, Krasicky G, Shah R, Walroth J, Greengart A, Moriel M, Challis T, Blood D, Rolnitzky L, DePuey G, Kuller L, Odoroff C, Schwartz R, Annechiarico R, Andrews M, Severski P, Ma G, Edwards J, Fischer K, Freedland K, Cobb L, Korsten J, Williams W, Algeo S, Chandysson P. Detection and Significance of Myocardial Ischemia in Stable Patients After Recovery From an Acute Coronary Event. JAMA 1993, 269: 2379-2385. DOI: 10.1001/jama.1993.03500180071037.Peer-Reviewed Original ResearchAcute coronary eventsSymptomatic myocardial ischemiaCoronary eventsST depressionMyocardial ischemiaNoninvasive testingExercise-induced ST depressionReversible thallium-201 defectsSubsequent coronary eventsHigh-risk subsetST-segment depressionThallium-201 scintigraphyThallium-201 defectsAcute myocardial infarctionNoninvasive test resultsPrimary eventFirst primary eventsPostcoronary patientsRecent hospitalizationSegment depressionUnstable anginaAmbulatory outpatientsCohort studyStable patientsExercise durationDetection and significance of myocardial ischemia in stable patients after recovery from an acute coronary event. Multicenter Myocardial Ischemia Research Group.
Moss A, Goldstein R, Hall W, Bigger J, Fleiss J, Greenberg H, Bodenheimer M, Krone R, Marcus F, Wackers F. Detection and significance of myocardial ischemia in stable patients after recovery from an acute coronary event. Multicenter Myocardial Ischemia Research Group. JAMA 1993, 269: 2379-85. PMID: 8479063, DOI: 10.1001/jama.269.18.2379.Peer-Reviewed Original ResearchConceptsAcute coronary eventsSymptomatic myocardial ischemiaCoronary eventsST depressionMyocardial ischemiaExercise-induced ST depressionReversible thallium-201 defectsSubsequent coronary eventsHigh-risk subsetST-segment depressionThallium-201 scintigraphyThallium-201 defectsAcute myocardial infarctionNoninvasive test resultsPrimary eventFirst primary eventsNon-invasive testingPostcoronary patientsRecent hospitalizationSegment depressionUnstable anginaAmbulatory outpatientsStable patientsExercise durationLung uptake
1991
Validation of continuous radionuclide left ventricular functioning monitoring in detecting silent myocardial ischemia during balloon angioplasty of the left anterior descending coronary artery
Kayden D, Remetz M, Cabin H, Deckelbaum L, Cleman M, Wackers F, Zaret B. Validation of continuous radionuclide left ventricular functioning monitoring in detecting silent myocardial ischemia during balloon angioplasty of the left anterior descending coronary artery. The American Journal Of Cardiology 1991, 67: 1339-1343. PMID: 2042565, DOI: 10.1016/0002-9149(91)90462-t.Peer-Reviewed Original ResearchConceptsSilent myocardial ischemiaLV ejection fractionLV dysfunctionMyocardial ischemiaEjection fractionLV functionBalloon inflationRelative end-systolic volumeTransient ST-segment depressionPercutaneous transluminal coronary angioplastyMean LV ejection fractionST-segment depressionContinuous electrocardiographic monitoringTransluminal coronary angioplastyLeft ventricular functionST-segment changesEnd-diastolic volumeEnd-systolic volumeIschemic decreaseCoronary angioplastyVentricular functionElectrocardiographic changesElectrocardiographic monitoringBalloon angioplastyCoronary artery