2001
Cardiac responses to insulin-induced hypoglycemia in nondiabetic and intensively treated type 1 diabetic patients
Russell R, Chyun D, Song S, Sherwin R, Tamborlane W, Lee F, Pfeifer M, Rife F, Wackers F, Young L. Cardiac responses to insulin-induced hypoglycemia in nondiabetic and intensively treated type 1 diabetic patients. AJP Endocrinology And Metabolism 2001, 281: e1029-e1036. PMID: 11595660, DOI: 10.1152/ajpendo.2001.281.5.e1029.Peer-Reviewed Original ResearchMeSH KeywordsAdultCardiac OutputCatecholaminesChemical PrecipitationDiabetes Mellitus, Type 1DiastoleEpinephrineFatty Acids, NonesterifiedFemaleGlucagonGlucose Clamp TechniqueHeartHeart RateHumansHydrocortisoneHypoglycemiaInsulinLactic AcidMaleNorepinephrinePolyethylene GlycolsStroke VolumeSystoleVentricular Function, LeftConceptsType 1 diabetic patientsInsulin-induced hypoglycemiaNondiabetic groupType 1 diabetesDiabetic subjectsEuglycemic hyperinsulinemiaDiabetic patientsNondiabetic subjectsCardiac responseLeft ventricular systolicHealthy nondiabetic subjectsEquilibrium radionuclide angiographyDiabetic groupDiastolic functionVentricular systolicCardiovascular consequencesVentricular functionBlunted increaseCardiac outputGlucagon concentrationsPlasma catecholaminesRadionuclide angiographyInsulin infusionEuglycemic conditionsHypoglycemia
2000
Assessment of left ventricular ejection fraction with quantitative gated SPECT: Accuracy and correlation with first-pass radionuclide angiography
Vallejo E, Dione D, Sinusas A, Wackers F. Assessment of left ventricular ejection fraction with quantitative gated SPECT: Accuracy and correlation with first-pass radionuclide angiography. Journal Of Nuclear Cardiology 2000, 7: 461-470. PMID: 11083195, DOI: 10.1067/mnc.2000.107820.Peer-Reviewed Original ResearchConceptsVentricular ejection fractionEjection fractionPatient studiesLeft ventricular ejection fractionExtracardiac activityFirst-pass radionuclide angiographyLarger end-diastolic volumeStress-induced ischemiaEnd-diastolic volumeQuantitative gated SPECTSingle photon emissionAbnormal LVEFNormal LVEFRadionuclide angiographyDiastolic volumeLVEFPerfusion defectsLVEF valuesSame patientHeart sizeLeft ventricleGated SPECTSPECT studiesQGSMean rest
1996
Prognostic value of noninvasive testing one year after orthotopic cardiac transplantation
Verhoeven P, Lee F, Ramahi T, Franco K, de Leon C, Amatruda J, Gorham N, Mattera J, Wackers F. Prognostic value of noninvasive testing one year after orthotopic cardiac transplantation. Journal Of The American College Of Cardiology 1996, 28: 183-189. PMID: 8752812, DOI: 10.1016/0735-1097(96)00094-0.Peer-Reviewed Original ResearchConceptsCoronary artery vasculopathyOrthotopic cardiac transplantationCardiac transplantationEquilibrium radionuclide angiographyPrognostic valueRadionuclide angiographyClinical variablesNoninvasive testingHuman leukocyte antigen mismatchesStress thallium-201 imagingThallium-201 myocardial perfusion imagingConsecutive transplant recipientsRoutine noninvasive testingStress myocardial imagingCold ischemic timeStress myocardial perfusionThallium-201 imagingTwo-dimensional echocardiographyNoninvasive diagnostic testingMyocardial perfusion imagingOnly significant predictorAntigen mismatchesLate deathsTransplant recipientsIschemic timeComparison and reproducibility of visual echocardiographic and quantitative radionyclide left ventricular ejection fractions
van Royen N, Jaffe C, Krumholz H, Johnson K, Lynch P, Natale D, Atkinson P, Demon P, Wackers F. Comparison and reproducibility of visual echocardiographic and quantitative radionyclide left ventricular ejection fractions. The American Journal Of Cardiology 1996, 77: 843-850. PMID: 8623737, DOI: 10.1016/s0002-9149(97)89179-5.Peer-Reviewed Original ResearchConceptsEquilibrium radionuclide angiographyVentricular ejection fractionEjection fractionRadionuclide angiographyEchocardiographic LVEFEquilibrium radionuclideRadionuclide LVEFClinical relevanceLeft ventricular ejection fractionCorrelation of LVEFDetermination of LVEFPatient management decisionsPotential clinical relevanceRelevant differencesInter-observer reproducibilityStable patientsLV functionLimits of agreementLVEFIndividual patientsRepeat assessmentEchocardiographyAngiographyBlinded analysisRepeat analysis
1988
Oral Terbutaline Augments Cardiac Performance in Chronic Obstructive Pulmonary Disease
Chan C, Loke J, Snyder P, Wackers F, Mattera J, Matthay R. Oral Terbutaline Augments Cardiac Performance in Chronic Obstructive Pulmonary Disease. The American Journal Of The Medical Sciences 1988, 296: 33-38. PMID: 3044105, DOI: 10.1097/00000441-198807000-00007.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseaseVentricular ejection fractionSubmaximal steady-state exerciseOral terbutalineSteady-state exerciseEjection fractionPulmonary diseaseSevere chronic obstructive pulmonary diseaseLeft ventricular ejection fractionFirst-pass radionuclide angiographySystolic pump performancePlacebo-controlled trialState exerciseExpiratory volumeBlood pressureCardiopulmonary effectsPlacebo dayHemodynamic measurementsVital capacityRadionuclide angiographyCardiac functionSubmaximal exerciseCardiac performanceHeart rate
1987
Right ventricular myocardial infarction with anterior wall left ventricular infarction: An autopsy study
Cabin H, Clubb K, Wackers F, Zaret B. Right ventricular myocardial infarction with anterior wall left ventricular infarction: An autopsy study. American Heart Journal 1987, 113: 16-23. PMID: 3799430, DOI: 10.1016/0002-8703(87)90004-4.Peer-Reviewed Original ResearchConceptsRight ventricular myocardial infarctionVentricular myocardial infarctionAnterior myocardial infarctionMyocardial infarctionVentricular infarctionVentricular free wallRadionuclide angiographyVentricular infarctAnterior wallFree wallInferior left ventricular infarctionRight ventricular free wallRight ventricular dysfunctionRight ventricular infarctRight ventricular necrosisLeft ventricular infarctionLeft ventricular free wallEquilibrium radionuclide angiographyVentricular necrosisVentricular dysfunctionAutopsy studyGlobal dysfunctionInfarctionTherapeutic implicationsClinical importance
1985
Short-lived 195mAu for evaluation of left ventricular function by first-pass radionuclide angiography.
Van der Wall E, van Lingen A, den Hollander W, Visser F, Heidendal G, Roos J, Wackers F. Short-lived 195mAu for evaluation of left ventricular function by first-pass radionuclide angiography. Nuklearmedizin - NuclearMedicine 1985, 24: 191-2. PMID: 4080562.Peer-Reviewed Original Research