2001
Selective use of single-photon emission computed tomography myocardial perfusion imaging in a chest pain center
Abbott B, Abdel-Aziz I, Nagula S, Monico E, Schriver J, Wackers F. Selective use of single-photon emission computed tomography myocardial perfusion imaging in a chest pain center. The American Journal Of Cardiology 2001, 87: 1351-1355. PMID: 11397352, DOI: 10.1016/s0002-9149(01)01551-x.Peer-Reviewed Original ResearchConceptsChest pain centerChest pain patientsCoronary artery diseasePain patientsSingle photon emissionChest painPain centerArtery diseaseMyocardial infarctionEmergency department chest pain centersEmergency department chest pain patientsTomography myocardial perfusion imagingTomography myocardial perfusionAcute myocardial infarctionMyocardial perfusion imagingSelective useCPC patientsNonischemic electrocardiogramHospital dischargeAppropriate patientsHospital admissionFinal diagnosisMyocardial perfusionPatientsPerfusion imaging
1993
Frequency and significance of right ventricular dysfunction during inferior wall left ventricular myocardial infarction treated with thrombolytic therapy (results from the Thrombolysis in Myocardial Infarction [TIMI] II trial)
Berger P, Ruocco N, Ryan T, Jacobs A, Zaret B, Wackers F, Frederick M, Faxon D, Group R. Frequency and significance of right ventricular dysfunction during inferior wall left ventricular myocardial infarction treated with thrombolytic therapy (results from the Thrombolysis in Myocardial Infarction [TIMI] II trial). The American Journal Of Cardiology 1993, 71: 1148-1152. PMID: 8097614, DOI: 10.1016/0002-9149(93)90637-r.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAngioplasty, Balloon, CoronaryCombined Modality TherapyConstriction, PathologicCoronary VesselsFemaleHeart DiseasesHeart VentriclesHumansMaleMiddle AgedMyocardial InfarctionRadionuclide VentriculographyThrombolytic TherapyTissue Plasminogen ActivatorVentricular Function, LeftVentricular Function, RightConceptsRV wall motion abnormalitiesRight ventricular dysfunctionRV dysfunctionVentricular myocardial infarctionWall motion abnormalitiesVentricular dysfunctionThrombolytic therapyRadionuclide ventriculographyMyocardial infarctionMotion abnormalitiesInferior wallLower mean left ventricular ejection fractionMean left ventricular ejection fractionLeft ventricular ejection fractionBaseline clinical characteristicsInfarct-related arteryMyocardial Infarction (TIMI) II trialVentricular ejection fractionEquilibrium radionuclide ventriculographyHospital complicationsMultivessel diseaseII trialClinical characteristicsHospital dischargeEjection fraction
1992
Assessment of global and regional left ventricular performance at rest and during exercise after thrombolytic therapy for acute myocardial infarction: Results of the Thrombolysis in Myocardial Infarction (TIMI) II study
Zaret B, Wackers F, Terrin M, Ross R, Weiss M, Slater J, Morrison J, Bourge R, Passamani E, Knatterud G, Braunwald E, Investigators. Assessment of global and regional left ventricular performance at rest and during exercise after thrombolytic therapy for acute myocardial infarction: Results of the Thrombolysis in Myocardial Infarction (TIMI) II study. The American Journal Of Cardiology 1992, 69: 1-9. PMID: 1729855, DOI: 10.1016/0002-9149(92)90667-n.Peer-Reviewed Original ResearchConceptsLV ejection fractionLeft ventricular performanceEjection fractionRegional left ventricular performanceRegional ejection fractionHospital dischargeThrombolytic therapyVentricular performanceTreatment strategiesStrategies patientsComparable work loadNormal exercise responseRegional LV performanceMyocardial Infarction (TIMI) II trialAcute myocardial infarctionHospital-discharged patientsConservative strategyII studyII trialDischarge patientsConservative patientsClinical benefitLV performanceExercise studiesMyocardial infarction
1990
Silent left ventricular dysfunction during routine activity after thrombolytic Therapy for acute myocardial infarction
Kayden D, Wackers F, Zaret B. Silent left ventricular dysfunction during routine activity after thrombolytic Therapy for acute myocardial infarction. Journal Of The American College Of Cardiology 1990, 15: 1500-1507. PMID: 2345230, DOI: 10.1016/0735-1097(90)92817-l.Peer-Reviewed Original ResearchConceptsTransient left ventricular dysfunctionLeft ventricular dysfunctionSilent left ventricular dysfunctionVentricular dysfunctionMyocardial infarctionCardiac eventsHospital dischargeEjection fractionThrombolytic therapySubmaximal supine bicycle exerciseNormal activityBaseline ejection fractionExercise test resultsSubsequent cardiac eventsSupine bicycle exerciseVentricular function monitoringAcute myocardial infarctionChest painPeak exerciseBicycle exerciseAmbulatory patientsElectrocardiographic changesPoor outcomePrognostic informationFunction monitoring
1989
Variables predictive of good functional outcome following thrombolytic therapy in the Thrombolysis in Myocardial Infarction phase II (TIMI II) pilot study
Rogers W, Bourge R, Papapietro S, Wackers F, Zaret B, Forman S, Dodge H, Robertson T, Passamani E, Braunwald E, Investigators F. Variables predictive of good functional outcome following thrombolytic therapy in the Thrombolysis in Myocardial Infarction phase II (TIMI II) pilot study. The American Journal Of Cardiology 1989, 63: 503-512. PMID: 2521976, DOI: 10.1016/0002-9149(89)90889-8.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionGood functional outcomeAngioplasty groupEjection fractionPeak exerciseHospital dischargeFunctional outcomePilot studyMyocardial Infarction Phase II (TIMI II) studyIntravenous recombinant tissue plasminogen activatorLeft ventricular ejection fractionPhase II pilot studyRecombinant tissue plasminogen activatorPhase II studyGood ventricular functionHours of onsetPercutaneous transluminal angioplastyRt-PA infusionVentricular ejection fractionObservational pilot studyST-segment elevationEquilibrium radionuclide ventriculographyGated equilibrium radionuclide ventriculographyAbsence of arrhythmiasTissue plasminogen activator