2020
A Time-Updated, Parsimonious Model to Predict AKI in Hospitalized Children
Sandokji I, Yamamoto Y, Biswas A, Arora T, Ugwuowo U, Simonov M, Saran I, Martin M, Testani JM, Mansour S, Moledina DG, Greenberg JH, Wilson FP. A Time-Updated, Parsimonious Model to Predict AKI in Hospitalized Children. Journal Of The American Society Of Nephrology 2020, 31: 1348-1357. PMID: 32381598, PMCID: PMC7269342, DOI: 10.1681/asn.2019070745.Peer-Reviewed Original ResearchConceptsExternal validation cohortValidation cohortElectronic health recordsSevere AKIClinical risk stratification toolDevelopment of AKIHealth recordsRisk stratification toolInternal validation cohortLength of stayCharacteristic curveElectronic medical recordsNeonatal AKIInpatient mortalitySecondary outcomesHospital admissionPrimary outcomeHospitalized childrenCreatinine valuesMedical recordsStudy populationAKICohortChildrenPredictive variables
2012
Predictors of Death and Dialysis in Severe AKI: The UPHS-AKI Cohort
Wilson FP, Yang W, Feldman HI. Predictors of Death and Dialysis in Severe AKI: The UPHS-AKI Cohort. Clinical Journal Of The American Society Of Nephrology 2012, 8: 527-537. PMID: 23258795, PMCID: PMC3613955, DOI: 10.2215/cjn.06450612.Peer-Reviewed Original ResearchConceptsSevere AKIC-indexIntensive care unit locationPredictors of deathEffective risk stratificationEndpoint of deathMore effective therapeutic interventionsHigh-risk subgroupsHarrell's C-indexLower overall mortalityProportional hazards modelEffective therapeutic interventionsPennsylvania Health SystemBaseline creatinineHospital AKIPressor medicationsSerum creatinineClinical factorsDerivation cohortHigher creatinineHospital admissionOverall mortalityLiver diseaseRisk stratificationValidation cohort