2011
Polymorphisms in immune function genes and non-Hodgkin lymphoma survival
Aschebrook-Kilfoy B, Zheng T, Foss F, Ma S, Han X, Lan Q, Holford T, Chen Y, Leaderer B, Rothman N, Zhang Y. Polymorphisms in immune function genes and non-Hodgkin lymphoma survival. Journal Of Cancer Survivorship 2011, 6: 102-114. PMID: 22113576, PMCID: PMC3326600, DOI: 10.1007/s11764-010-0164-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCase-Control StudiesConnecticutCytokinesDisease-Free SurvivalFemaleGene FrequencyGenotypeHumansKaplan-Meier EstimateLymphoma, Non-HodgkinMiddle AgedModels, GeneticPolymorphism, Single NucleotidePrognosisProportional Hazards ModelsSocioeconomic FactorsSurvival AnalysisSurvivorsYoung AdultConceptsNon-Hodgkin lymphomaNHL survivalHazard ratioCytokine genesNon-Hodgkin lymphoma survivalCox proportional hazards modelIncident NHL casesConnecticut Tumor RegistryDisease-free survivalKaplan-Meier curvesRisk of deathProportional hazards modelCombination of polymorphismsImmune function genesIL6 genotypeNHL prognosisTumor RegistryHistologic typeTumor characteristicsDecreased riskSecondary cancersNHL casesTumor interactionCancer occurrenceLymphoma survival
2010
Cytokine polymorphisms in Th1/Th2 pathway genes, body mass index, and risk of non-Hodgkin lymphoma
Chen Y, Zheng T, Lan Q, Foss F, Kim C, Chen X, Dai M, Li Y, Holford T, Leaderer B, Boyle P, Chanock SJ, Rothman N, Zhang Y. Cytokine polymorphisms in Th1/Th2 pathway genes, body mass index, and risk of non-Hodgkin lymphoma. Blood 2010, 117: 585-590. PMID: 20952689, PMCID: PMC3031482, DOI: 10.1182/blood-2010-07-295097.Peer-Reviewed Original ResearchConceptsBody mass indexNon-Hodgkin lymphomaAG/GGB-cell lymphomaMass indexCommon B-cell lymphoma subtypesSmall lymphocytic lymphoma/chronic lymphocytic leukemiaRisk of NHLMarginal zone B-cell lymphomaCT/TT genotypesB-cell lymphoma subtypesT-cell lymphomaCase-control studyCT/TTChronic lymphocytic leukemiaNHL overallConnecticut womenNHL riskLymphocytic leukemiaLymphoma subtypesTh2 cytokine genesFollicular lymphomaTT genotypeSignificant interactionLymphoma
2002
Immunologic mechanisms of extracorporeal photochemotherapy in chronic graft-versus-host disease
Gorgun G, Miller KB, Foss FM. Immunologic mechanisms of extracorporeal photochemotherapy in chronic graft-versus-host disease. Blood 2002, 100: 941-947. PMID: 12130506, DOI: 10.1182/blood-2002-01-0068.Peer-Reviewed Original ResearchConceptsMixed lymphocyte reactionAntigen-presenting dendritic cellsDendritic cellsT cellsChronic graftHost diseaseClinical responseDC populationsActivity of DCsAllogeneic bone marrow transplantationCD4/CD8 ratioMonocytic dendritic cellsAllogeneic T cellsEffector T cellsNatural killer cellsBone marrow transplantationTh2 cytokine profileChronic GVHDCD8 ratioCytokine profileECP therapyImmunologic mechanismsLymphocyte subpopulationsEffector lymphocytesKiller cells