2023
Body Composition, Coronary Microvascular Dysfunction, and Future Risk of Cardiovascular Events Including Heart Failure
Souza A, Rosenthal M, Moura F, Divakaran S, Osborne M, Hainer J, Dorbala S, Blankstein R, Di Carli M, Taqueti V. Body Composition, Coronary Microvascular Dysfunction, and Future Risk of Cardiovascular Events Including Heart Failure. JACC Cardiovascular Imaging 2023, 17: 179-191. PMID: 37768241, PMCID: PMC10922555, DOI: 10.1016/j.jcmg.2023.07.014.Peer-Reviewed Original ResearchMeSH KeywordsCoronary Artery DiseaseFemaleHeart FailureHumansMaleMiddle AgedObesityPredictive Value of TestsRisk FactorsStroke VolumeVentricular Function, LeftConceptsCoronary microvascular dysfunctionVisceral adipose tissueAssociated with coronary microvascular dysfunctionCoronary flow reserveBody mass indexLow coronary flow reserveSubcutaneous adipose tissueCoronary artery diseaseAdverse eventsPositron emission tomographyObese patientsMicrovascular dysfunctionVisceral adipose tissue cross-sectional areaCardiovascular eventsHeart failurePreserved left ventricular ejection fractionAdverse outcomesSkeletal muscleArtery diseaseFlow-limiting coronary artery diseaseBody compositionAssociated with body compositionEvaluation of coronary artery diseaseStress positron emission tomographyEmission tomography
2017
Sarcopenia, but not excess weight or increased caloric intake, is associated with coronary subclinical atherosclerosis in the very elderly
Campos A, Moura F, Santos S, Freitas W, Sposito A, Study O. Sarcopenia, but not excess weight or increased caloric intake, is associated with coronary subclinical atherosclerosis in the very elderly. Atherosclerosis 2017, 258: 138-144. PMID: 28129889, DOI: 10.1016/j.atherosclerosis.2017.01.005.Peer-Reviewed Original ResearchMeSH KeywordsAbsorptiometry, PhotonAdiposityAge FactorsAged, 80 and overAsymptomatic DiseasesBody CompositionCoronary AngiographyCoronary Artery DiseaseCross-Sectional StudiesEndothelium, VascularEnergy IntakeExercise TestExercise ToleranceFemaleGeriatric AssessmentHumansLogistic ModelsMaleMultidetector Computed TomographyMultivariate AnalysisMuscle StrengthMuscle, SkeletalNutrition AssessmentNutritional StatusOdds RatioOverweightProspective StudiesRisk FactorsSarcopeniaVasodilationWeight GainConceptsCoronary heart diseaseAssociated with subclinical atherosclerosisCoronary calcium scoreFlow-mediated dilationExcess weightSubclinical atherosclerosisOdds ratioFatty massMuscle massPhysical performance testsCoronary heart disease riskElderly individualsRisk of coronary heart diseaseAssociated with coronary heart diseaseCaloric intakeIncreased risk of coronary heart diseaseStudy of CohortsEndothelial dysfunctionCross-sectional studySkeletal muscle indexAssociated with flow-mediated dilationGait speedCardiac computed tomographyReduction of muscle massMultivariate regression model
2015
Coronary artery calcification score is an independent predictor of the no-reflow phenomenon after reperfusion therapy in acute myocardial infarction
Modolo R, Figueiredo V, Moura F, Almeida B, Quinaglia e Silva J, Nadruz W, Lemos P, Coelho O, Blaha M, Sposito A. Coronary artery calcification score is an independent predictor of the no-reflow phenomenon after reperfusion therapy in acute myocardial infarction. Coronary Artery Disease 2015, 26: 562-566. PMID: 26010531, DOI: 10.1097/mca.0000000000000269.Peer-Reviewed Original ResearchConceptsCoronary artery calcification scoreST-elevation myocardial infarctionCoronary artery calcificationMyocardial blush gradeTIMI flowAssociated with impaired reperfusionST-elevation myocardial infarction patientsCoronary angiographic severityCardiac computed tomographyConsecutive STEMI patientsTIMI flow ratesNonculprit coronary arteryCoronary thrombus burdenArtery calcification scoreAcute coronary syndromeNo-reflow phenomenonHigher heart rateCoronary blood flowCAC scoreOptimal reperfusionCalcification scoreClinical characteristicsAngiographic severityBlush gradeSTEMI patients