2015
Racial and Ethnic Differences in Breast Cancer Survival: Mediating Effect of Tumor Characteristics and Sociodemographic and Treatment Factors
Warner ET, Tamimi RM, Hughes ME, Ottesen RA, Wong YN, Edge SB, Theriault RL, Blayney DW, Niland JC, Winer EP, Weeks JC, Partridge AH. Racial and Ethnic Differences in Breast Cancer Survival: Mediating Effect of Tumor Characteristics and Sociodemographic and Treatment Factors. Journal Of Clinical Oncology 2015, 33: 2254-2261. PMID: 25964252, PMCID: PMC4486344, DOI: 10.1200/jco.2014.57.1349.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAsianBiomarkers, TumorBlack or African AmericanBody Mass IndexBreast NeoplasmsCause of DeathDisease-Free SurvivalEthnicityFemaleHealth Status DisparitiesHealthcare DisparitiesHispanic or LatinoHumansLogistic ModelsMiddle AgedMultivariate AnalysisNeoplasm GradingNeoplasm StagingProportional Hazards ModelsRacial GroupsRisk FactorsSocioeconomic FactorsTime FactorsTreatment OutcomeTriple Negative Breast NeoplasmsUnited StatesWhite PeopleConceptsBreast cancer-specific survivalEstrogen receptor-positive tumorsCancer-specific survivalReceptor-positive tumorsBreast cancer survivalTumor characteristicsCancer survivalBreast cancerNational Comprehensive Cancer Network centersBreast cancer-specific deathHuman epidermal growth factor receptorCancer-specific deathMultivariable adjusted modelsYear of diagnosisBody mass indexProportional hazards regressionEpidermal growth factor receptorRace/ethnicityGrowth factor receptorHazards regressionMass indexRisk factorsSurvival differencesLike tumorsHigh risk
2013
Racial/Ethnic Differences in Receipt of Timely Adjuvant Therapy for Older Women with Breast Cancer: Are Delays Influenced by the Hospitals Where Patients Obtain Surgical Care?
Freedman RA, He Y, Winer EP, Keating NL. Racial/Ethnic Differences in Receipt of Timely Adjuvant Therapy for Older Women with Breast Cancer: Are Delays Influenced by the Hospitals Where Patients Obtain Surgical Care? Health Services Research 2013, 48: 1669-1683. PMID: 23663229, PMCID: PMC3796107, DOI: 10.1111/1475-6773.12063.Peer-Reviewed Original ResearchConceptsTreatment delayBreast cancerTimely adjuvant therapyEnd Results (SEER) dataMultivariable logistic regressionEthnic differencesRace/ethnicityAdjuvant chemotherapyAdjuvant therapyMedicare claimsSurgical careHigher oddsOlder womenHispanic womenStage IHospitalLogistic regressionRacial disparitiesWomenPatientsBlack womenCancerCareResult dataImportant contributor
2010
The association of race/ethnicity, insurance status, and socioeconomic factors with breast cancer care
Freedman RA, Virgo KS, He Y, Pavluck AL, Winer EP, Ward EM, Keating NL. The association of race/ethnicity, insurance status, and socioeconomic factors with breast cancer care. Cancer 2010, 117: 180-189. PMID: 20939011, DOI: 10.1002/cncr.25542.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBlack PeopleBreast NeoplasmsChemotherapy, AdjuvantCombined Modality TherapyEthnicityFemaleHealthcare DisparitiesHispanic or LatinoHormonesHumansInsurance CoverageInsurance, HealthMastectomyRacial GroupsRadiotherapy, AdjuvantSocial ClassSocioeconomic FactorsWhite PeopleConceptsDefinitive locoregional therapyHormone receptor testingArea-level socioeconomic statusBreast cancer careRace/ethnicityHormonal therapyLocoregional therapyReceptor testingSocioeconomic statusCancer careHispanic womenAdjuvant hormonal therapyAdjuvant systemic therapyInvasive breast cancerBreast cancer patientsMultivariate logistic regressionBreast cancer treatmentReceipt of careEligible patientsSystemic therapyBlack raceCancer patientsInsurance statusNational cohortBreast cancer
2009
Racial Differences in Definitive Breast Cancer Therapy in Older Women
Keating NL, Kouri E, He Y, Weeks JC, Winer EP. Racial Differences in Definitive Breast Cancer Therapy in Older Women. Medical Care 2009, 47: 765-773. PMID: 19536008, DOI: 10.1097/mlr.0b013e31819e1fe7.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedBlack or African AmericanBreast NeoplasmsChi-Square DistributionFemaleHealth Services ResearchHealthcare DisparitiesHospitalsHumansLogistic ModelsMastectomyMedicareMultivariate AnalysisPractice Patterns, Physicians'Quality of Health CareSEER ProgramSensitivity and SpecificitySocioeconomic FactorsUnited StatesWhite PeopleConceptsHigh-volume hospitalsDefinitive primary therapyHigh-quality hospitalsBreast-conserving surgeryBreast cancer therapyBreast cancerPrimary therapyWhite womenRacial disparitiesStage I/II breast cancerBlack womenPrimary breast cancer therapyEarly-stage breast cancerLow-volume hospitalsBreast cancer patientsBreast cancer surgeryPatterns of careSEER-Medicare databaseCancer therapyPopulation-based sampleOlder Black womenDefinitive therapyVolume hospitalsCancer surgeryCancer patients
2008
Reducing Disparities in Breast Cancer Care—A Daunting but Essential Responsibility
Freedman RA, Winer EP. Reducing Disparities in Breast Cancer Care—A Daunting but Essential Responsibility. Journal Of The National Cancer Institute 2008, 100: 1661-1663. PMID: 19033563, DOI: 10.1093/jnci/djn412.Peer-Reviewed Original ResearchRacial Differences in Clinical Outcomes From Metastatic Breast Cancer: A Pooled Analysis of CALGB 9342 and 9840—Cancer and Leukemia Group B
Polite BN, Cirrincione C, Fleming GF, Berry DA, Seidman A, Muss H, Norton L, Shapiro C, Bakri K, Marcom K, Lake D, Schwartz JH, Hudis C, Winer EP. Racial Differences in Clinical Outcomes From Metastatic Breast Cancer: A Pooled Analysis of CALGB 9342 and 9840—Cancer and Leukemia Group B. Journal Of Clinical Oncology 2008, 26: 2659-2665. PMID: 18509177, PMCID: PMC4830463, DOI: 10.1200/jco.2007.13.9782.Peer-Reviewed Original ResearchConceptsMetastatic breast cancerHazard of deathTreatment failureBreast cancerOverall survivalClinical outcomesLeukemia Group B trialAfrican AmericansLeukemia Group BMedian overall survivalTreatment-related toxicityObserved survival differencesTime of presentationAfrican American patientsRacial differencesOverall responseAfrican American womenLarge cooperative groupsMetastatic settingProtocol treatmentPrognostic factorsStudy cohortSubsequent therapyShorter survivalPooled analysis
2006
Molecular subtypes of breast cancer in relation to paclitaxel response and outcomes in women with metastatic disease: results from CALGB 9342
Harris LN, Broadwater G, Lin NU, Miron A, Schnitt SJ, Cowan D, Lara J, Bleiweiss I, Berry D, Ellis M, Hayes DF, Winer EP, Dressler L. Molecular subtypes of breast cancer in relation to paclitaxel response and outcomes in women with metastatic disease: results from CALGB 9342. Breast Cancer Research 2006, 8: r66. PMID: 17129383, PMCID: PMC1797029, DOI: 10.1186/bcr1622.Peer-Reviewed Original ResearchConceptsMetastatic breast cancerTriple-negative tumorsOverall survivalBreast cancerP53 statusNegative tumorsHER2 statusHormone receptorsHormone receptor statusShorter median timeDoses of paclitaxelLonger overall survivalHER2-positive tumorsAfrican American patientsHormone receptor expressionPrimary tumor tissuesAdvanced diseaseMetastatic diseaseShorter OSReceptor statusMedian timeTreatment failureShorter survivalCaucasian patientsPathology reports