2018
Variability in Ejection Fraction Measured By Echocardiography, Gated Single-Photon Emission Computed Tomography, and Cardiac Magnetic Resonance in Patients With Coronary Artery Disease and Left Ventricular Dysfunction
Pellikka PA, She L, Holly TA, Lin G, Varadarajan P, Pai RG, Bonow RO, Pohost GM, Panza JA, Berman DS, Prior DL, Asch FM, Borges-Neto S, Grayburn P, Al-Khalidi HR, Miszalski-Jamka K, Desvigne-Nickens P, Lee KL, Velazquez EJ, Oh JK. Variability in Ejection Fraction Measured By Echocardiography, Gated Single-Photon Emission Computed Tomography, and Cardiac Magnetic Resonance in Patients With Coronary Artery Disease and Left Ventricular Dysfunction. JAMA Network Open 2018, 1: e181456-e181456. PMID: 30646130, PMCID: PMC6324278, DOI: 10.1001/jamanetworkopen.2018.1456.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionCoronary artery diseaseCardiovascular magnetic resonanceVentricular ejection fractionArtery diseaseCore laboratorySingle photon emissionVentricular dysfunctionEjection fractionBland-Altman plotsLVEF measurementsAssociation of LVEFGated single-photon emissionIschemic heart failureLeft ventricular dysfunctionSubset of patientsOptimal treatment strategyImaging modalitiesMulticenter diagnostic studyCardiac magnetic resonanceInternational multicenter studyLVEF dataMost patientsHeart failureSurgical treatment
2015
Sex differences in clinical characteristics and outcomes after myocardial infarction: insights from the Valsartan in Acute Myocardial Infarction Trial (VALIANT)
Lam CS, McEntegart M, Claggett B, Liu J, Skali H, Lewis E, Køber L, Rouleau J, Velazquez E, Califf R, McMurray JJ, Pfeffer M, Solomon S. Sex differences in clinical characteristics and outcomes after myocardial infarction: insights from the Valsartan in Acute Myocardial Infarction Trial (VALIANT). European Journal Of Heart Failure 2015, 17: 301-312. PMID: 25655011, DOI: 10.1002/ejhf.238.Peer-Reviewed Original ResearchConceptsAcute Myocardial Infarction trialMyocardial Infarction trialVentricular systolic dysfunctionHeart failureMyocardial infarctionSystolic dysfunctionClinical characteristicsVentricular volumeKillip class III/IVLeft ventricular systolic dysfunctionRisk of HFClass III/IVHigher long-term riskSmaller left ventricular volumesSimilar ejection fractionLong-term mortalityPost-infarction anginaRisk of hospitalizationSubset of patientsNon-fatal outcomesLong-term riskLeft ventricular volumeAssociation of sexMore comorbiditiesCardiovascular death
2014
Predictors and Progression of Aortic Stenosis in Patients With Preserved Left Ventricular Ejection Fraction
Ersboll M, Schulte PJ, Al Enezi F, Shaw L, Køber L, Kisslo J, Siddiqui I, Piccini J, Glower D, Harrison JK, Bashore T, Risum N, Jollis JG, Velazquez EJ, Samad Z. Predictors and Progression of Aortic Stenosis in Patients With Preserved Left Ventricular Ejection Fraction. The American Journal Of Cardiology 2014, 115: 86-92. PMID: 25456876, DOI: 10.1016/j.amjcard.2014.09.049.Peer-Reviewed Original ResearchConceptsModerate aortic stenosisAortic stenosisMild aortic stenosisVentricular ejection fractionMean gradientHemodynamic progressionEjection fractionClinical variablesLeft ventricular ejection fractionSevere aortic stenosisBaseline clinical variablesSubset of patientsRate of progressionEchocardiographic surveillanceRenal dysfunctionUnselected cohortAccelerated progressionLongitudinal linear regression modelsCurrent guidelinesDisease progressionRetrospective analysisPatientsSignificant interactionProgressionBaseline