2008
Left atrial remodelling in patients with myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: the VALIANT Echo Study
Meris A, Amigoni M, Uno H, Thune JJ, Verma A, Køber L, Bourgoun M, McMurray JJ, Velazquez EJ, Maggioni AP, Ghali J, Arnold JM, Zelenkofske S, Pfeffer MA, Solomon SD. Left atrial remodelling in patients with myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: the VALIANT Echo Study. European Heart Journal 2008, 30: 56-65. PMID: 19001474, DOI: 10.1093/eurheartj/ehn499.Peer-Reviewed Original ResearchConceptsHigh-risk myocardial infarctionMyocardial infarctionHeart failureIndependent predictorsLA sizeHF hospitalizationVentricular dysfunctionFirst monthBaseline independent predictorsVALIANT Echo studyLeft ventricular dysfunctionGlomerular filtration rateLeft atrial sizeBody surface areaBaseline LAVICause deathAtrial sizeLA enlargementAtrial remodellingEchocardiography studyLA remodellingLA volumeAdverse outcomesLV massFiltration rate
2007
The Relationship Between Renal Function and Cardiac Structure, Function, and Prognosis After Myocardial Infarction The VALIANT Echo Study
Verma A, Anavekar NS, Meris A, Thune JJ, Arnold JM, Ghali JK, Velazquez EJ, McMurray JJ, Pfeffer MA, Solomon SD. The Relationship Between Renal Function and Cardiac Structure, Function, and Prognosis After Myocardial Infarction The VALIANT Echo Study. Journal Of The American College Of Cardiology 2007, 50: 1238-1245. PMID: 17888840, DOI: 10.1016/j.jacc.2007.06.018.Peer-Reviewed Original ResearchConceptsLeft ventricular mass indexRenal impairmentHeart failureMyocardial infarctionRenal functionCardiac structureReduced eGFRSystolic functionLA volumeSmaller LVHigher left ventricular mass indexLarger left atrial volumeInfarct segment lengthMitral deceleration timeVALIANT Echo studyMultivariable Cox regressionAdverse cardiovascular outcomesLeft ventricular dysfunctionNormal renal functionOutcome of deathRight ventricular functionVentricular mass indexGlomerular filtration rateAdditional prognostic informationLarger LA volumes