2023
Reply Long-Term Patient Outcomes After Femoropopliteal Peripheral Vascular Intervention in Patients With Intermittent Claudication
Altin S, Curtis J. Reply Long-Term Patient Outcomes After Femoropopliteal Peripheral Vascular Intervention in Patients With Intermittent Claudication. JACC Cardiovascular Interventions 2023, 16: 2336. PMID: 37758390, DOI: 10.1016/j.jcin.2023.08.027.Peer-Reviewed Original ResearchSupervised Exercise Therapy Versus Percutaneous Transluminal Angioplasty for Claudication by Level of Disease: A Systematic Review and Meta-Analysis
Kapadia S, Huang H, Parise H, Ismayl M, Ahmed Z, Tirziu D, Altin S. Supervised Exercise Therapy Versus Percutaneous Transluminal Angioplasty for Claudication by Level of Disease: A Systematic Review and Meta-Analysis. The American Journal Of Cardiology 2023, 205: 403-405. PMID: 37659260, DOI: 10.1016/j.amjcard.2023.08.044.Peer-Reviewed Original ResearchPulmonary Artery Catheter Use and Outcomes in Patients With ST-Elevation Myocardial Infarction and Cardiogenic Shock Treated With Impella (a Nationwide Analysis from the United States)
Ismayl M, Hussain Y, Aboeata A, Walters R, Naidu S, Messenger J, Basir M, Rao S, Goldsweig A, Altin S. Pulmonary Artery Catheter Use and Outcomes in Patients With ST-Elevation Myocardial Infarction and Cardiogenic Shock Treated With Impella (a Nationwide Analysis from the United States). The American Journal Of Cardiology 2023, 203: 304-314. PMID: 37517125, DOI: 10.1016/j.amjcard.2023.06.117.Peer-Reviewed Original ResearchConceptsST-elevation myocardial infarctionCardiogenic shockCatheter useHospital mortalityPA catheterCatheter placementInpatient costsMyocardial infarctionPulmonary artery catheter placementPulmonary artery catheter useNational Inpatient Sample databaseMultivariate logistic regression analysisPA catheter placementUse of ImpellaSimilar complication ratesMechanical circulatory supportLength of stayLogistic regression analysisHospital complicationsHospital lengthBaseline characteristicsComplication rateHematologic complicationsMortality benefitSecondary outcomesLong-Term Patient Outcomes After Femoropopliteal Peripheral Vascular Intervention in Patients With Intermittent Claudication
Altin S, Parise H, Hess C, Rosenthal N, Creager M, Aronow H, Curtis J. Long-Term Patient Outcomes After Femoropopliteal Peripheral Vascular Intervention in Patients With Intermittent Claudication. JACC Cardiovascular Interventions 2023, 16: 1668-1678. PMID: 37438035, DOI: 10.1016/j.jcin.2023.05.001.Peer-Reviewed Original ResearchConceptsPeripheral vascular interventionsIndex limb amputationAmputation rateIntermittent claudicationMajor amputationRevascularization ratesVascular interventionsCox proportional hazards regressionLong-term patient outcomesMajor amputation rateProportional hazards regressionKaplan-Meier estimatesFurther risk factorsLimb amputation rateClinical trial dataIndex limbIC patientsSecondary outcomesPrimary outcomeHazards regressionRisk factorsPatient outcomesLimb amputationHealthcare databasesPatientsUse of telemedicine facilitated by trained telepresenters to manage advanced peripheral artery disease in rural areas
Breen T, Peake J, Keefe H, Moran J, Kunjukutty F, Pfau S, Altin S. Use of telemedicine facilitated by trained telepresenters to manage advanced peripheral artery disease in rural areas. Vascular Medicine 2023, 28: 239-240. PMID: 36628596, DOI: 10.1177/1358863x221148797.Peer-Reviewed Original ResearchRepresentation of Women in Cardiology Academic Faculty Ranks
Altin S, Parikh P, Squeri E, Douglas P, Wang D, Mehran R. Representation of Women in Cardiology Academic Faculty Ranks. The American Journal Of Cardiology 2023, 190: 96-97. PMID: 36608436, DOI: 10.1016/j.amjcard.2022.12.007.Peer-Reviewed Original Research
2022
Sex-Based Differences in Periprocedural Complications Following Lower Extremity Peripheral Vascular Intervention
Altin S, Gitto M, Secemsky E, Rao S, Hess C. Sex-Based Differences in Periprocedural Complications Following Lower Extremity Peripheral Vascular Intervention. Circulation Cardiovascular Interventions 2022, 15: e011768. PMID: 35938403, DOI: 10.1161/circinterventions.121.011768.Peer-Reviewed Original ResearchConceptsLower extremity peripheral vascular interventionsPeripheral vascular interventionsSymptomatic peripheral artery diseasePeripheral artery diseasePeriprocedural complicationsArtery diseaseHigh riskHospital mortalityKnee amputationFemale sexVascular interventionsVascular Quality Initiative registryAccess site bleedingAccess site complicationsPercutaneous coronary interventionCoronary artery diseaseSex-based outcomesMultivariate logistic regressionWarrants further investigationSex-based differencesBaseline patientSite bleedingCoronary interventionSite complicationsContemporary cohortMeta-Analysis Comparing Catheter-Directed Thrombolysis Versus Systemic Anticoagulation Alone for Submassive Pulmonary Embolism
Ismayl M, Machanahalli Balakrishna A, Aboeata A, Gupta T, Young M, Altin S, Aronow H, Goldsweig A. Meta-Analysis Comparing Catheter-Directed Thrombolysis Versus Systemic Anticoagulation Alone for Submassive Pulmonary Embolism. The American Journal Of Cardiology 2022, 178: 154-162. PMID: 35778309, DOI: 10.1016/j.amjcard.2022.06.004.Peer-Reviewed Original ResearchConceptsSubmassive pulmonary embolismSystemic anticoagulationMinor bleedingPulmonary embolismBlood transfusionRisk ratioSimilar bleeding ratesRight ventricular dysfunctionFirst-line therapyConfidence intervalsRandom-effects modelHospital mortalityMajor bleedingHemodynamic instabilityVentricular dysfunctionOptimal therapyBleeding rateIndependent reviewersSystematic reviewBleedingMortalityPatientsGoogle ScholarAnticoagulationTransfusionStatins and statin intensity in peripheral artery disease.
Sagris M, Katsaros I, Giannopoulos S, Rosenberg RD, Altin SE, Rallidis L, Mena-Hurtado C, Armstrong EJ, Kokkinidis DG. Statins and statin intensity in peripheral artery disease. Vasa 2022, 51: 198-211. PMID: 35673949, DOI: 10.1024/0301-1526/a001012.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsPeripheral artery diseaseLow-intensity statinsLoss of patencyStatin useStatin doseIntensity statinsArtery diseaseFirst-line lipid-lowering therapyAdverse cardiovascular eventsAmputation-free survivalHigher statin doseLipid-lowering therapyMyocardial infarction rateRisk of amputationImpact of statinsStatin intensityCardiovascular eventsPAD patientsCardiovascular deathCardiovascular mortalityCause mortalityInfarction rateIschemia patientsStatin treatmentCalling time on the use of war metaphors in covid-19
Clark K, Altin S. Calling time on the use of war metaphors in covid-19. The BMJ 2022, 377: o1214. PMID: 35562115, DOI: 10.1136/bmj.o1214.Peer-Reviewed Original ResearchTransradial versus transfemoral approach for percutaneous coronary intervention in patients with ST-elevation myocardial infarction complicated by cardiogenic shock: a systematic review and meta-analysis
Ahsan M, Ahmad S, Latif A, Lateef N, Ahsan M, Abusnina W, Nathan S, Altin S, Kolte D, Messenger J, Tannenbaum M, Goldsweig A. Transradial versus transfemoral approach for percutaneous coronary intervention in patients with ST-elevation myocardial infarction complicated by cardiogenic shock: a systematic review and meta-analysis. European Heart Journal - Quality Of Care And Clinical Outcomes 2022, 8: 640-650. PMID: 35460230, PMCID: PMC9442849, DOI: 10.1093/ehjqcco/qcac018.Peer-Reviewed Original ResearchConceptsST-elevation myocardial infarctionPercutaneous coronary interventionAccess site bleedingCardiogenic shockTransfemoral accessTransradial accessTIMI3 flowSite bleedingCoronary interventionProcedural successContrast volumeYear mortalityMyocardial infarctionRisk ratioSystematic reviewProcedural success rateConfidence intervalsCoronary flow gradeRandom-effects modelFlow gradeTransfemoral approachRetrospective studyLower mortalityBleedingMortalityImplementation of supervised exercise therapy in a veteran population with symptomatic claudication
Altin S, Schneider MD, Parise H, Banerjee S, Wu WC, Meadows JL, Pfau S, Keefe H, Armstrong EJ. Implementation of supervised exercise therapy in a veteran population with symptomatic claudication. Vascular Medicine 2022, 27: 136-141. PMID: 35225695, DOI: 10.1177/1358863x211073622.Peer-Reviewed Original ResearchConceptsExercise treadmill testingExercise therapyMetabolic equivalentsIntermittent claudicationExercise capacityTreadmill testingAnkle-brachial indexIntermittent claudication symptomsMale veteran patientsSupervised exercise therapySymptomatic intermittent claudicationVascular specialty clinicsLow patient adherenceClaudication symptomsSymptomatic claudicationExercise groupVeteran patientsPatient adherenceRisk stratificationTherapy referralSpecialty clinicProvider awarenessVeteran populationClaudicationTherapySex Differences in Peripheral Artery Disease
Pabon M, Cheng S, Altin S, Sethi S, Nelson M, Moreau K, Hamburg N, Hess C. Sex Differences in Peripheral Artery Disease. Circulation Research 2022, 130: 496-511. PMID: 35175843, PMCID: PMC8919803, DOI: 10.1161/circresaha.121.320702.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseArtery diseaseManagement of PADSuch sex-based differencesNontraditional risk factorsSex differencesLack of diagnosisSex-based differencesImportant sex differencesIschemic cardiovascularPAD prevalenceVascular stressorSubstantial morbidityClinical presentationClinical manifestationsRisk factorsPrevalent conditionLimb eventsOverall populationVascular substratesDiseaseSex variationWomenCurrent knowledgeManifestationsAngiographic Lesion Discordance in Women Presenting With Ischemic Heart Disease: Comparison of Visual Assessment, Quantitative Coronary Angiography, and Quantitative Flow Ratio.
Gitto M, Saito Y, Taoutel R, Schneider MD, Papoutsidakis N, Ardito S, Henry G, Cristea E, Lansky AJ, Altin SE. Angiographic Lesion Discordance in Women Presenting With Ischemic Heart Disease: Comparison of Visual Assessment, Quantitative Coronary Angiography, and Quantitative Flow Ratio. Journal Of Invasive Cardiology 2022, 34: e202-e209. PMID: 35089162, DOI: 10.25270/jic/21.00146.Peer-Reviewed Original ResearchConceptsQuantitative coronary angiographyIschemic heart diseaseQuantitative flow ratioStress perfusion imagingDiameter stenosisCoronary angiographyIschemic symptomsCoronary revascularizationHeart diseasePerfusion imagingStenosis severityIndependent core laboratoryCohort of womenVisual assessmentCoronary stenosis severityConsecutive patientsAngiographic severityCoronary stenosisLesion assessmentClinical practiceCore laboratoryLesionsAngiographyWomenBlinded operators
2021
Outcomes of mechanical circulatory support for acute myocardial infarction complicated by cardiogenic shock
Kim Y, Shapero K, Ahn SS, Goldsweig AM, Desai N, Altin SE. Outcomes of mechanical circulatory support for acute myocardial infarction complicated by cardiogenic shock. Catheterization And Cardiovascular Interventions 2021, 99: 658-663. PMID: 34156755, PMCID: PMC10877703, DOI: 10.1002/ccd.29834.Peer-Reviewed Original ResearchConceptsIntra-aortic balloon pumpMechanical circulatory supportAcute kidney injuryNational Inpatient SampleHospital mortalityAcute myocardial infarctionCardiogenic shockKidney injuryCirculatory supportMyocardial infarctionNational Cardiovascular Data RegistryPropensity scoreEfficacy of ImpellaPremier Healthcare DatabaseRetrospective cohort studyHigher hospital costsLength of stayReal-world observational dataImpella useCohort studyImpella deviceBalloon pumpPrimary outcomeInpatient SampleRisk factorsRacial and ethnic disparities in coronary, vascular, structural, and congenital heart disease
Grines CL, Klein AJ, Bauser‐Heaton H, Alkhouli M, Katukuri N, Aggarwal V, Altin SE, Batchelor WB, Blankenship JC, Fakorede F, Hawkins B, Hernandez GA, Ijioma N, Keeshan B, Li J, Ligon RA, Pineda A, Sandoval Y, Young MN. Racial and ethnic disparities in coronary, vascular, structural, and congenital heart disease. Catheterization And Cardiovascular Interventions 2021, 98: 277-294. PMID: 33909339, DOI: 10.1002/ccd.29745.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsTranscatheter aortic valve replacementNon-Hispanic whitesCardiovascular diseaseCongenital heart interventionsInterventional cardiovascular therapyAortic valve replacementCongenital heart diseaseRate of diagnosisCause of deathInterventional cardiology patientsPrevalence of diseaseTAVR patientsValve replacementExcess morbidityTreatment disparitiesCardiology patientsHeart diseaseCardiovascular AngiographyClinical careAverage ageCardiovascular therapyPatientsHeart interventionsEthnic disparitiesUnderserved populations
2020
Predictors of Underutilization of Medical Therapy in Patients Undergoing Endovascular Revascularization for Peripheral Artery Disease
Altin S, Castro-Dominguez Y, Kennedy K, Orion K, Lanksy A, Abbott J, Aronow H. Predictors of Underutilization of Medical Therapy in Patients Undergoing Endovascular Revascularization for Peripheral Artery Disease. JACC Cardiovascular Interventions 2020, 13: 2911-2918. PMID: 33357529, DOI: 10.1016/j.jcin.2020.08.036.Peer-Reviewed Original ResearchConceptsGuideline-directed medical therapyGDMT prescriptionPeripheral artery diseaseAntiplatelet agentsArtery diseaseLower extremity peripheral vascular interventionsAngiotensin receptor blocker useSymptomatic peripheral artery diseaseTraditional atherosclerotic risk factorsChronic limb-threatening ischemiaEnd-stage renal diseaseAtherosclerotic disease burdenDischarge prescription ratesGuideline-recommended therapiesAngiotensin receptor blockersAtherosclerotic risk factorsReceptor blocker useVascular Study GroupLimb-threatening ischemiaPeripheral vascular interventionsVascular Quality InitiativeCongestive heart failureCoronary artery diseaseMultivariate logistic regressionBlocker useSeasonal variation in U.S. hospitalizations for chronic limb‐threatening ischemia
Altin SE, Kim YG, Aronow HD, Armstrong EJ, Goldsweig AM, Dardik A, Lanksy AJ, Mena‐Hurtado C, Abbott JD. Seasonal variation in U.S. hospitalizations for chronic limb‐threatening ischemia. Catheterization And Cardiovascular Interventions 2020, 96: 1473-1480. PMID: 32902126, DOI: 10.1002/ccd.29261.Peer-Reviewed Original ResearchConceptsCritical limb-threatening ischemiaLimb-threatening ischemiaNational Inpatient SampleMinor amputationChronic limb-threatening ischemiaUtilization Project National Inpatient SampleProvider education effortsCoronary artery diseaseAmputation rateHospital mortalityImportant comorbidityDiabetic statusOverall cohortSecondary outcomesArtery diseaseHospital admissionPrimary outcomeHospitalization incidenceU.S. hospitalizationsDiagnosis codesInpatient SampleHigher oddsAdmission seasonHealthcare costsMortality rateUtility of Intravascular Ultrasound in Peripheral Vascular Interventions: Systematic Review and Meta-Analysis
Sheikh AB, Anantha-Narayanan M, Smolderen KG, Jelani QU, Nagpal S, Schneider M, Llanos F, Ionescu C, Regan C, Attaran R, Altin SE, Mena-Hurtado C. Utility of Intravascular Ultrasound in Peripheral Vascular Interventions: Systematic Review and Meta-Analysis. Vascular And Endovascular Surgery 2020, 54: 413-422. PMID: 32338163, DOI: 10.1177/1538574420920998.Peer-Reviewed Original ResearchConceptsPeripheral vascular interventionsPeriprocedural adverse eventsVascular complicationsAdverse eventsIntravascular ultrasoundPrimary patencyCause mortalityTechnical successMyocardial infarctionObservational studyVascular interventionsEnd pointSimilar patency ratesSimilar primary patencyPrimary end pointRate of reinterventionSecondary end pointsPeripheral arterial diseaseImproved clinical outcomesIVUS groupAmputation rateArterial diseaseClinical outcomesPatency ratesLower risk
2019
Sex Differences in the Pursuit of Interventional Cardiology as a Subspecialty Among Cardiovascular Fellows-in-Training
Yong CM, Abnousi F, Rzeszut AK, Douglas PS, Harrington RA, Mehran R, Grines C, Altin SE, Duvernoy CS, Council A, Innovations S. Sex Differences in the Pursuit of Interventional Cardiology as a Subspecialty Among Cardiovascular Fellows-in-Training. JACC Cardiovascular Interventions 2019, 12: 219-228. PMID: 30660463, DOI: 10.1016/j.jcin.2018.09.036.Peer-Reviewed Original Research