1989
Insulin resistance in uremia: An in vivo and in vitro study
Stein P, Hunt W, Johnson C, DeFronzo R, Smith J. Insulin resistance in uremia: An in vivo and in vitro study. Metabolism 1989, 38: 562-567. PMID: 2657327, DOI: 10.1016/0026-0495(89)90217-5.Peer-Reviewed Original ResearchConceptsUremic ratsAbility of insulinInsulin resistanceSoleus muscleTotal body glucose disposalEuglycemic insulin clamp techniqueInsulin clamp techniqueUremic rat modelHepatic glucose productionPair-fed controlsChronic uremiaGlucose disposalRat modelGlucose metabolismClamp techniqueGlucose productionMetabolic defectsInsulinRatsUremiaGlycogen synthesisGlucose oxidationMuscleVivoOxidative pathway
1985
Is glucose intolerance harmful for the uremic patient?
DeFronzo R, Smith J. Is glucose intolerance harmful for the uremic patient? Kidney International Supplement 1985, 17: s88-97. PMID: 3912590.Peer-Reviewed Original ResearchEffect of insulin on the distribution and disposition of glucose in man.
Ferrannini E, Smith J, Cobelli C, Toffolo G, Pilo A, DeFronzo R. Effect of insulin on the distribution and disposition of glucose in man. Journal Of Clinical Investigation 1985, 76: 357-364. PMID: 3894421, PMCID: PMC423783, DOI: 10.1172/jci111969.Peer-Reviewed Original Research