Diana Athonvarangkul, MD, PhD
Instructor of Medicine (Endocrinology)Cards
About
Research
Publications
2024
Intracellular calcium links milk stasis to lysosome-dependent cell death during early mammary gland involution
Jeong J, Lee J, Talaia G, Kim W, Song J, Hong J, Yoo K, Gonzalez D, Athonvarangkul D, Shin J, Dann P, Haberman A, Kim L, Ferguson S, Choi J, Wysolmerski J. Intracellular calcium links milk stasis to lysosome-dependent cell death during early mammary gland involution. Cellular And Molecular Life Sciences 2024, 81: 29. PMID: 38212474, PMCID: PMC10784359, DOI: 10.1007/s00018-023-05044-8.Peer-Reviewed Original Research
2023
Improved extremity tissue oxygenation with short-term exposure to textiles embedded with far infrared light emitting thermoactive particles in patients with diabetes mellitus
Athonvarangkul D, Wang K, Deng Y, Inzucchi S, Mayerson A. Improved extremity tissue oxygenation with short-term exposure to textiles embedded with far infrared light emitting thermoactive particles in patients with diabetes mellitus. Diabetes And Vascular Disease Research 2023, 20: 14791641231170282. PMID: 37073436, PMCID: PMC10123901, DOI: 10.1177/14791641231170282.Peer-Reviewed Original ResearchCrosstalk within a brain-breast-bone axis regulates mineral and skeletal metabolism during lactation
Athonvarangkul D, Wysolmerski J. Crosstalk within a brain-breast-bone axis regulates mineral and skeletal metabolism during lactation. Frontiers In Physiology 2023, 14: 1121579. PMID: 36875035, PMCID: PMC9979219, DOI: 10.3389/fphys.2023.1121579.Peer-Reviewed Original ResearchBone lossExcess bone lossExcessive bone lossPostmenopausal osteoporosisBone turnoverRare entityMineral metabolismSkeletal metabolismNew therapiesBone qualityCalcium demandOsteoporosisMammary glandCalcium deliveryBone axisReversible physiological responseLactationHormonal signalsCurrent knowledgeMetabolismPhysiological responsesPregnancyHypothalamusPathophysiologyTherapyHypercalcemia of Malignancy
Corin H. DEGROOT’S ENDOCRINOLOGY, 8TH EDITION. Acta Endocrinol (Buchar). 2022 Jul-Sep;18(3):406. doi: 10.4183/aeb.2022.406. PMCID: PMC9867825.Chapters
2020
New Therapies for Hypophosphatemia-Related to FGF23 Excess
Athonvarangkul D, Insogna KL. New Therapies for Hypophosphatemia-Related to FGF23 Excess. Calcified Tissue International 2020, 108: 143-157. PMID: 32504139, DOI: 10.1007/s00223-020-00705-3.BooksConceptsTumor-induced osteomalaciaCutaneous skeletal hypophosphatemia syndromeEpidermal nevus syndromeAutosomal dominant hypophosphatemic ricketsAutosomal recessive hypophosphatemic ricketsHypophosphatemic ricketsForms of FGF23Treatment of XLHActive comparator trialsMainstay of therapyMonoclonal blocking antibodyNew treatment modalitiesMcCune-Albright syndromeRenal phosphate wastingRecessive hypophosphatemic ricketsDominant hypophosphatemic ricketsFGF23 excessComparator trialsSkeletal complicationsChronic hypophosphatemiaMusculoskeletal syndromeOngoing trialsClinical presentationTreatment modalitiesClinical trialsSAT-258 Surprising Transformation of a Microprolactinoma to a Macroprolactinoma
Athonvarangkul D, Hosier H, Wojeck B, Inzucchi S. SAT-258 Surprising Transformation of a Microprolactinoma to a Macroprolactinoma. Journal Of The Endocrine Society 2020, 4: sat-258. PMCID: PMC7207434, DOI: 10.1210/jendso/bvaa046.1057.Peer-Reviewed Original ResearchPRL levelsDA therapySignificant interval growthDopamine agonist therapyLeft cavernous sinusPituitary hormone levelsHigh PRL levelsNormal withdrawalAgonist therapyRepeat MRIMenstrual irregularitiesIndolent neoplasmSecondary amenorrheaCyclic bleedingHealthy babyOptic chiasmInterval growthCavernous sinusPituitary microadenomaHormone levelsSuprasellar cisternBenign tumorsMacroprolactinomasMicroprolactinomasRare caseMON-LB125 Dka From a Ketogenic Diet and Intermittent Fasting or Ketosis-Prone Diabetes?
Athonvarangkul D, Gossmann M, Cohen K. MON-LB125 Dka From a Ketogenic Diet and Intermittent Fasting or Ketosis-Prone Diabetes? Journal Of The Endocrine Society 2020, 4: mon-lb125. PMCID: PMC7209289, DOI: 10.1210/jendso/bvaa046.2112.Peer-Reviewed Original ResearchDiabetic ketoacidosisBeta-cell functionUnits/dayIntermittent fastingNutritional ketosisKetogenic dietCauses of DKAAnion gap metabolic acidosisWeight lossBeta-cell autoantibodiesRecurrence of hyperglycemiaGap metabolic acidosisCell functionInsulin AbsInsulin dripKetosis-ProneMetab.Prediabetic patientsCell autoantibodiesInsulin therapySubcutaneous insulinSGLT2 inhibitorsNormal lactateSerum ketonesUrinary ketones
2015
Autophagy in the CNS and Periphery Coordinate Lipophagy and Lipolysis in the Brown Adipose Tissue and Liver
Martinez-Lopez N, Garcia-Macia M, Sahu S, Athonvarangkul D, Liebling E, Merlo P, Cecconi F, Schwartz GJ, Singh R. Autophagy in the CNS and Periphery Coordinate Lipophagy and Lipolysis in the Brown Adipose Tissue and Liver. Cell Metabolism 2015, 23: 113-127. PMID: 26698918, PMCID: PMC4715637, DOI: 10.1016/j.cmet.2015.10.008.Peer-Reviewed Original ResearchMeSH KeywordsAdipocytes, BrownAdipose Tissue, BrownAmino Acid SequenceAnimalsAutophagyCold TemperatureFemaleHypothalamusLipaseLipid DropletsLipolysisLiverLysosomesMaleMice, Inbred C57BLMice, TransgenicMicrotubule-Associated ProteinsMolecular Sequence DataNeuronsOxygen ConsumptionPro-OpiomelanocortinConceptsBrown adipose tissuePOMC neuronsLipid utilizationPeripheral tissuesAdipose tissueProopiomelanocortin neuronsInter-organ communicationCentral autophagyCold-induced activationATGLAutophagosome marker LC3LipolysisNeuronsTargeted activationLipase ATGLLipophagyIntegrative physiologyTissueMiceLiverAutophagyAutophagy proteinsCytosolic lipasesCold inducesActivation