2019
Classification of Background Parenchymal Uptake on Molecular Breast Imaging Using a Convolutional Neural Network
Carter RE, Attia ZI, Geske JR, Conners AL, Whaley DH, Hunt KN, O’Connor M, Rhodes DJ, Hruska CB. Classification of Background Parenchymal Uptake on Molecular Breast Imaging Using a Convolutional Neural Network. JCO Clinical Cancer Informatics 2019, 3: 1-11. PMID: 30807208, PMCID: PMC6446086, DOI: 10.1200/cci.18.00133.Peer-Reviewed Original ResearchConceptsConvolutional neural networkNeural networkDeep learning modelsImage convolutionLearning modelModel performanceBackground parenchymal uptakeTesting dataComputer algorithmAlgorithmExpert radiologistsNetworkDirect matchingDirect matchAccuracyImagesClassificationResearch purposesPerformanceBreast imagingConvolutionEncodingMatchingModelingTraining
2016
Benefit-to–Radiation Risk for Breast Screening Tests Is a Flawed Concept
Rhodes DJ, Hruska CB, Conners AL, Hunt KN, O'Connor MK. Benefit-to–Radiation Risk for Breast Screening Tests Is a Flawed Concept. Radiology 2016, 281: 978-980. PMID: 27870632, DOI: 10.1148/radiol.2016161334.Peer-Reviewed Original ResearchDense Breasts: What Do Our Patients Need to Be Told and Why?
Throckmorton AD, Rhodes DJ, Hughes KS, Degnim AC, Dickson-Witmer D. Dense Breasts: What Do Our Patients Need to Be Told and Why? Annals Of Surgical Oncology 2016, 23: 3119-3127. PMID: 27401446, DOI: 10.1245/s10434-016-5400-3.Peer-Reviewed Original ResearchConceptsBreast cancer prevention strategiesEvidence-based consensus guidelinesDense breastsBreast cancer risk assessmentOnly risk factorCancer prevention strategiesCancer risk assessmentDelaying diagnosisCertain patientsConsensus guidelinesRisk factorsDensity notificationSupplemental imagingPrevention strategiesPatientsBreast densityBreastRisk assessmentCancerDiagnosisWomen
2012
Evaluation of Molecular Breast Imaging in Women Undergoing Myocardial Perfusion Imaging with Tc-99m Sestamibi
Hruska CB, Rhodes DJ, Collins DA, Tortorelli CL, Askew JW, O'Connor MK. Evaluation of Molecular Breast Imaging in Women Undergoing Myocardial Perfusion Imaging with Tc-99m Sestamibi. Journal Of Women's Health 2012, 21: 730-738. PMID: 22404787, DOI: 10.1089/jwh.2011.3267.Peer-Reviewed Original ResearchConceptsMolecular breast imagingBreast diseaseBreast cancerDiagnostic yieldMyocardial perfusionHigh-risk benign breast lesionsMyocardial perfusion stress testingRecent negative mammogramStress myocardial perfusionHigh diagnostic yieldStress myocardial perfusion studyBenign breast lesionsNumber of cancersMyocardial perfusion studiesBreast imagingNew cancersRecent mammogramSestamibi injectionNegative mammogramUnnecessary workupPerfusion studiesBreast lesionsCancerIsotope injectionWomen
2010
Comparison of radiation exposure and associated radiation‐induced cancer risks from mammography and molecular imaging of the breasta)
O'Connor MK, Li H, Rhodes DJ, Hruska CB, Clancy CB, Vetter RJ. Comparison of radiation exposure and associated radiation‐induced cancer risks from mammography and molecular imaging of the breasta). Medical Physics 2010, 37: 6187-6198. PMID: 21302775, PMCID: PMC2997811, DOI: 10.1118/1.3512759.Peer-Reviewed Original ResearchConceptsBenefit/risk ratioMolecular breast imagingCumulative cancer incidenceCancer incidenceRisk ratioAge groupsExcess absolute risk (EAR) modelsAnnual digital mammographyAttributable risk modelRadiation-induced cancer riskBreast cancer incidenceBreast-specific gammaPositron emission mammographyBEIR VII reportRadiation-induced cancerDense breast tissueAbsolute risk modelsMBq FScreening groupAnnual screeningConventional dosesMBq TcLifetime riskBreast cancerAge 40
2002
Identifying and Counseling Women at Increased Risk for Breast Cancer
Rhodes DJ. Identifying and Counseling Women at Increased Risk for Breast Cancer. Mayo Clinic Proceedings 2002, 77: 355-361. PMID: 11936931, DOI: 10.4065/77.4.355.Peer-Reviewed Original ResearchConceptsBreast cancerRisk factorsBreast cancer prevention clinical trialsCancer prevention clinical trialsPossible risk factorsPrevention clinical trialsRisk reductionRisk assessment toolLifestyle modificationProphylactic mastectomyClose surveillanceClinical trialsFamily historyCounseling womenNumerical risk estimatesCancerRisk estimatesIndividual riskSuch womenWomenRiskAbsence of consensusComplex family historiesAssessment toolOptions
2000
Breast cancer prevention trials
Rhodes D, Hartmann L, Perez E. Breast cancer prevention trials. Current Oncology Reports 2000, 2: 558-565. PMID: 11122893, DOI: 10.1007/s11912-000-0110-0.Peer-Reviewed Original ResearchConceptsBreast Cancer Prevention TrialCancer Prevention TrialBreast cancer incidenceBreast cancerPrevention trialsCancer incidenceBowel Project Breast Cancer Prevention TrialPrimary breast cancer preventionNational Surgical Adjuvant BreastEffectiveness of raloxifeneEfficacy of tamoxifenBreast cancer preventionHormone replacement therapyAdjuvant BreastPostmenopausal womenRandomized trialsReplacement therapyDrug therapyCancer preventionStudy populationEligibility criteriaChemopreventive agentsTamoxifenTreatment planRaloxifene