2012
Proof of concept for low‐dose molecular breast imaging with a dual‐head CZT gamma camera. Part II. Evaluation in patients
Hruska CB, Weinmann AL, Skjerseth C, Wagenaar EM, Conners AL, Tortorelli CL, Maxwell RW, Rhodes DJ, O'Connor MK. Proof of concept for low‐dose molecular breast imaging with a dual‐head CZT gamma camera. Part II. Evaluation in patients. Medical Physics 2012, 39: 3476-3483. PMID: 22755727, PMCID: PMC3376157, DOI: 10.1118/1.4719959.Peer-Reviewed Original ResearchConceptsMolecular breast imagingMBq TcDiagnostic accuracyIntrareader agreementMedian lesion sizeLesion detectionPatient studiesEffective radiation doseTelluride gamma cameraSimilar diagnostic accuracyAdequate lesion detectionAdjunct screening techniqueGamma cameraAdministered dosesCount densityClinical careSeparate cohortLesion sizeMBq injectionMolecular breastLow dosesPatientsDense breastsBreast lesionsDoses
2010
Comparison of radiation exposure and associated radiation‐induced cancer risks from mammography and molecular imaging of the breasta)
O'Connor MK, Li H, Rhodes DJ, Hruska CB, Clancy CB, Vetter RJ. Comparison of radiation exposure and associated radiation‐induced cancer risks from mammography and molecular imaging of the breasta). Medical Physics 2010, 37: 6187-6198. PMID: 21302775, PMCID: PMC2997811, DOI: 10.1118/1.3512759.Peer-Reviewed Original ResearchConceptsBenefit/risk ratioMolecular breast imagingCumulative cancer incidenceCancer incidenceRisk ratioAge groupsExcess absolute risk (EAR) modelsAnnual digital mammographyAttributable risk modelRadiation-induced cancer riskBreast cancer incidenceBreast-specific gammaPositron emission mammographyBEIR VII reportRadiation-induced cancerDense breast tissueAbsolute risk modelsMBq FScreening groupAnnual screeningConventional dosesMBq TcLifetime riskBreast cancerAge 40
2007
Molecular Breast Imaging: Advantages and Limitations of a Scintimammographic Technique in Patients with Small Breast Tumors
O'Connor MK, Phillips SW, Hruska CB, Rhodes DJ, Collins DA. Molecular Breast Imaging: Advantages and Limitations of a Scintimammographic Technique in Patients with Small Breast Tumors. The Breast Journal 2007, 13: 3-11. PMID: 17214787, DOI: 10.1111/j.1524-4741.2006.00356.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingCarcinoma, LobularCarcinoma, PapillaryFemaleHumansMammographyMiddle AgedPredictive Value of TestsRadionuclide ImagingSensitivity and SpecificityTechnetium Tc 99m SestamibiUltrasonographyConceptsMolecular breast imagingSmall breast tumorsBreast tumorsEvidence of cancerFalse-positive scansLarger patient populationMalignant breast tumorsStandard mammographic viewsMBq TcOccult tumorsPatient populationMalignant tumorsPositive scansPatientsTumorsBreast tissueSubjective discomfortBiopsySurgeryMammographic viewsGamma cameraBreast imagingBreast thicknessPreliminary studyRegular detection