Patterns of loco-regional progression and patient outcomes after definitive-dose radiation therapy for anaplastic thyroid cancer
Bronk J, Augustyn A, Mohamed A, Fuller C, Garden A, Moreno A, Lee A, Morrison W, Phan J, Reddy J, Rosenthal D, Spiotto M, Frank S, Dadu R, Busaidy N, Zafereo M, Wang J, Maniakas A, Ferrarotto R, Iyer P, Cabanillas M, Gunn G. Patterns of loco-regional progression and patient outcomes after definitive-dose radiation therapy for anaplastic thyroid cancer. Radiotherapy And Oncology 2024, 202: 110602. PMID: 39489425, DOI: 10.1016/j.radonc.2024.110602.Peer-Reviewed Original ResearchIntensity modulated radiation therapyLoco-regional progressionAnaplastic thyroid cancerTarget volumeConcurrent chemotherapyRadiation therapyThyroid cancerHigh dosesAreas of gross diseaseMedian progression free survivalMedian IMRT doseGross tumor volumeMedian overall survivalProgression free survivalNeo-adjuvant strategiesDeformable image registrationIntensive treatment scheduleLevels II-VDiagnostic CTsIMRT dosePlanning CTsGross diseaseLocoregional diseaseUnresectable diseaseFree survival