Christina Johns, MD
About
Research
Publications
2018
Amygdala functional connectivity is associated with social impairments in preterm born young adults
Johns CB, Lacadie C, Vohr B, Ment LR, Scheinost D. Amygdala functional connectivity is associated with social impairments in preterm born young adults. NeuroImage Clinical 2018, 21: 101626. PMID: 30545688, PMCID: PMC6413301, DOI: 10.1016/j.nicl.2018.101626.Peer-Reviewed Original ResearchConceptsVineland Adaptive Behavior ScalesYouth Self-ReportAmygdala functional connectivitySocial impairmentChild Behavior ChecklistFunctional connectivityAmygdala connectivityPreterm participantsSocial functioningSocial functioning correlatesSocial functioning deficitsResting-state functional magnetic resonanceFunctional magnetic resonancePreterm-born adolescentsAdaptive Behavior ScalesAge 16Term-born peersEmotional developmentPreterm birth experienceParent reportDevelopmental trajectoriesRisk of depressionLate adolescentsBehavior ChecklistSelf-Report
2017
Dietary Fatty Acid Modification for the Treatment of Aspirin-Exacerbated Respiratory Disease: A Prospective Pilot Trial
Schneider T, Johns C, Palumbo M, Murphy K, Cahill K, Laidlaw T. Dietary Fatty Acid Modification for the Treatment of Aspirin-Exacerbated Respiratory Disease: A Prospective Pilot Trial. The Journal Of Allergy And Clinical Immunology In Practice 2017, 6: 825-831. PMID: 29133219, PMCID: PMC5945343, DOI: 10.1016/j.jaip.2017.10.011.Peer-Reviewed Original ResearchConceptsAspirin-exacerbated respiratory diseaseUrinary leukotriene EDietary interventionLeukotriene ERespiratory diseaseTreatment of AERDDietary fatty acid modificationAsthma Control Questionnaire scoreNasal Outcome Test (SNOT-22) scoresAdjunct treatment optionProspective pilot trialPatient-reported questionnaireFatty acid consumptionTreatment of aspirinOutcome Test scoresAdult patientsAdverse eventsLung functionPrimary outcomeClinical efficacyVital capacityTreatment optionsWomen's HospitalIntervention periodPilot trialAltered amygdala functional connectivity subserves maladaptive social behavior in prematurely born young adults (P3.194)
Johns C, Scheinost D, Lacadie C, Vohr B, Ment L. Altered amygdala functional connectivity subserves maladaptive social behavior in prematurely born young adults (P3.194). Neurology 2017, 88 DOI: 10.1212/wnl.88.16_supplement.p3.194.Peer-Reviewed Original Research
2016
Automated identification of an aspirin-exacerbated respiratory disease cohort
Cahill K, Johns C, Cui J, Wickner P, Bates D, Laidlaw T, Beeler P. Automated identification of an aspirin-exacerbated respiratory disease cohort. Journal Of Allergy And Clinical Immunology 2016, 139: 819-825.e6. PMID: 27567328, PMCID: PMC5266739, DOI: 10.1016/j.jaci.2016.05.048.Peer-Reviewed Original ResearchConceptsAspirin-exacerbated respiratory diseaseAllergist/immunologistElectronic health recordsPositive predictive valueEHRs of patientsPredictive valueHigh positive predictive valueAnti-inflammatory drugsAERD diagnosisChart reviewNasal polyposisClinical featuresCohort ANasal polypsPartners HealthCare SystemPatient RegistryPatient notesUndiagnosed casesDisease cohortRespiratory diseaseRespiratory reactionsInformatics algorithmClinical expertsSearch termsHealth records
2015
Daily Low-Dose Aspirin Use Leads to a Delay in Diagnosis of Aspirin Exacerbated Respiratory Disease
Lee-Sarwar K, Johns C, Laidlaw T, Cahill K. Daily Low-Dose Aspirin Use Leads to a Delay in Diagnosis of Aspirin Exacerbated Respiratory Disease. Journal Of Allergy And Clinical Immunology 2015, 135: ab244. DOI: 10.1016/j.jaci.2014.12.1731.Peer-Reviewed Original ResearchTolerance of daily low-dose aspirin does not preclude aspirin-exacerbated respiratory disease
Lee-Sarwar K, Johns C, Laidlaw T, Cahill K. Tolerance of daily low-dose aspirin does not preclude aspirin-exacerbated respiratory disease. The Journal Of Allergy And Clinical Immunology In Practice 2015, 3: 449-451. PMID: 25634222, PMCID: PMC4426242, DOI: 10.1016/j.jaip.2015.01.007.Peer-Reviewed Original Research
2014
Food Allergy Epidemiology and Natural History
Savage J, Johns C. Food Allergy Epidemiology and Natural History. Immunology And Allergy Clinics Of North America 2014, 35: 45-59. PMID: 25459576, PMCID: PMC4254585, DOI: 10.1016/j.iac.2014.09.004.Peer-Reviewed Original ResearchBacterial metabolites of diet-derived lignans and isoflavones inversely associate with asthma and wheezing
Cardet J, Johns C, Savage J. Bacterial metabolites of diet-derived lignans and isoflavones inversely associate with asthma and wheezing. Journal Of Allergy And Clinical Immunology 2014, 135: 267-269.e14. PMID: 25190319, PMCID: PMC4289106, DOI: 10.1016/j.jaci.2014.07.035.Peer-Reviewed Original ResearchElevated Total Serum IgE in Nonatopic Patients with Aspirin-exacerbated Respiratory Disease
Johns C, Laidlaw T. Elevated Total Serum IgE in Nonatopic Patients with Aspirin-exacerbated Respiratory Disease. American Journal Of Rhinology And Allergy 2014, 28: 287-289. PMID: 25197914, DOI: 10.2500/ajra.2014.28.4054.Peer-Reviewed Original ResearchConceptsAspirin-exacerbated respiratory diseaseElevated total serum IgETotal serum IgESubset of patientsSerum IgERespiratory diseaseNonsteroidal anti-inflammatory drugsOral aspirin challengeHistory of atopyAbsence of atopyRecurrent nasal polypsSubgroup of patientsAllergic-like reactionsAnti-inflammatory drugsPositive test resultsAspirin challengeNonatopic patientsCommon aeroallergensSamter's triadEntire cohortNasal polypsMean bloodAtopyPatientsClinical relevanceAccess to health care and food in children with food allergy
Johns C, Savage J. Access to health care and food in children with food allergy. Journal Of Allergy And Clinical Immunology 2014, 133: 582-585.e5. PMID: 24636475, PMCID: PMC3960290, DOI: 10.1016/j.jaci.2013.12.006.Peer-Reviewed Original Research