2016
Kidney Outcomes 5 Years After Pediatric Cardiac Surgery: The TRIBE-AKI Study
Greenberg JH, Zappitelli M, Devarajan P, Thiessen-Philbrook HR, Krawczeski C, Li S, Garg AX, Coca S, Parikh CR. Kidney Outcomes 5 Years After Pediatric Cardiac Surgery: The TRIBE-AKI Study. JAMA Pediatrics 2016, 170: 1071-1078. PMID: 27618162, PMCID: PMC5476457, DOI: 10.1001/jamapediatrics.2016.1532.Peer-Reviewed Original ResearchConceptsLong-term kidney outcomesAcute kidney injuryChronic kidney diseasePediatric cardiac surgeryPerioperative acute kidney injuryPostoperative acute kidney injuryCardiac surgeryKidney diseaseKidney outcomesKidney injuryHigh short-term morbidityProspective multicenter cohort studySerum creatinine riseMulticenter cohort studyShort-term morbidityAge 1 monthOutcomes 5 yearsRenal outcomesPreoperative baselineCohort studyPediatric centersCardiopulmonary bypassCreatinine risePerson followPerson visits
2011
Postoperative Biomarkers Predict Acute Kidney Injury and Poor Outcomes after Pediatric Cardiac Surgery
Parikh CR, Devarajan P, Zappitelli M, Sint K, Thiessen-Philbrook H, Li S, Kim RW, Koyner JL, Coca SG, Edelstein CL, Shlipak MG, Garg AX, Krawczeski CD. Postoperative Biomarkers Predict Acute Kidney Injury and Poor Outcomes after Pediatric Cardiac Surgery. Journal Of The American Society Of Nephrology 2011, 22: 1737-1747. PMID: 21836147, PMCID: PMC3171944, DOI: 10.1681/asn.2010111163.Peer-Reviewed Original ResearchConceptsUrine neutrophil gelatinase-associated lipocalinNeutrophil gelatinase-associated lipocalinUrine IL-18Acute kidney injurySevere acute kidney injuryUrine NGAL levelsPediatric cardiac surgeryIL-18NGAL levelsCardiac surgeryPoor outcomeHospital stayKidney injuryPlasma neutrophil gelatinase-associated lipocalinIntensive care unit staySubsequent acute kidney injuryEarly postoperative measuresPlasma NGAL levelsLonger hospital stayMulticenter cohort studyGelatinase-associated lipocalinCongenital cardiac lesionsNet reclassification improvementPostoperative biomarkersUnit stay
2008
Abstract 4574: Validation of Early Biomarkers of Acute Kidney Injury After Pediatric Cardiac Surgery
Krawczeski C, Devarajan P, Nguyen M, Kathman T, Wang Z, Parikh C. Abstract 4574: Validation of Early Biomarkers of Acute Kidney Injury After Pediatric Cardiac Surgery. Circulation 2008, 118 DOI: 10.1161/circ.118.suppl_18.s_914-a.Peer-Reviewed Original ResearchAcute kidney injuryCardiac surgerySerum creatinineKidney injuryEarly biomarkers of acute kidney injuryDuration of acute kidney injuryBiomarker of acute kidney injuryModerate acute kidney injurySeverity of acute kidney injuryPrognosis of acute kidney injuryClinical acute kidney injuryInitiation of cardiopulmonary bypassLength of hospital stayCongenital heart diseasePeak serum creatininePediatric cardiac surgeryA1MA1-acid glycoproteinClinical laboratory platformsSELDI-TOF-MSAmerican Heart AssociationDialysis requirementPediatric patientsCardiopulmonary bypassHospital stay