2023
Cutaneous T-cell lymphoma with CNS involvement: a case series and review of the literature
Preston J, Jansen C, Kosaraju S, Niyogusaba T, Zhuang T, Iwamoto S, Hutto S, Lechowicz M, Allen P. Cutaneous T-cell lymphoma with CNS involvement: a case series and review of the literature. CNS Oncology 2023, 12: cns105. PMID: 37877303, PMCID: PMC10701703, DOI: 10.2217/cns-2023-0014.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaT-cell lymphomaCentral nervous systemCNS metastasesCases of cutaneous T-cell lymphomaDevelopment of CNS metastasesCentral nervous system involvementRare hematologic malignancyCNS-directed therapyDegree of remissionHematologic malignanciesProgressive diseaseMedian timeCase seriesTreatment responseTherapeutic guidelinesPathological characteristicsCutaneous lesionsMetastasisNervous systemLymphomaPatientsSurvivalInvolvementRemission
2019
An intra-tumoral niche maintains and differentiates stem-like CD8 T cells
Jansen C, Prokhnevska N, Master V, Sanda M, Carlisle J, Bilen M, Cardenas M, Wilkinson S, Lake R, Sowalsky A, Valanparambil R, Hudson W, McGuire D, Melnick K, Khan A, Kim K, Chang Y, Kim A, Filson C, Alemozaffar M, Osunkoya A, Mullane P, Ellis C, Akondy R, Im S, Kamphorst A, Reyes A, Liu Y, Kissick H. An intra-tumoral niche maintains and differentiates stem-like CD8 T cells. Nature 2019, 576: 465-470. PMID: 31827286, PMCID: PMC7108171, DOI: 10.1038/s41586-019-1836-5.Peer-Reviewed Original ResearchConceptsCD8 T cellsStem-like CD8 T cellsT cellsStem-like T cellsCD8 T cell infiltrationCD8 T cell responsesMechanism of immune escapeTumor-infiltrating lymphocytesT cell infiltrationT cell responsesStem-like cellsSurvival benefitImmune nicheProgressive diseaseImmune escapeTumor typesTumorCD8Human cancersDifferentiation processLymphocytesPatientsCancerInfiltrationSurvival