Neoadjuvant Cabozantinib in an Unresectable Locally Advanced Renal Cell Carcinoma Patient Leads to Downsizing of Tumor Enabling Surgical Resection: A Case Report
Bilen M, Jiang J, Jansen C, Brown J, Harik L, Sekhar A, Kissick H, Maithel S, Kucuk O, Carthon B, Master V. Neoadjuvant Cabozantinib in an Unresectable Locally Advanced Renal Cell Carcinoma Patient Leads to Downsizing of Tumor Enabling Surgical Resection: A Case Report. Frontiers In Oncology 2021, 10: 622134. PMID: 33598435, PMCID: PMC7882722, DOI: 10.3389/fonc.2020.622134.Peer-Reviewed Original ResearchRenal cell carcinomaMetastatic renal cell carcinomaMagnetic resonance imagingSurgical resectionNeoadjuvant settingCell carcinomaAdvanced renal cell carcinoma patientsLocally advanced renal cell carcinomaLeft renal cell carcinomaUnresectable renal cell carcinomaAdvanced renal cell carcinomaInvasion of adjacent structuresRenal cell carcinoma patientsNeoadjuvant systemic therapySecond-line settingSplenic flexure of colonTumor size reductionCell carcinoma patientsTail of pancreasReduced tumor growthAdjacent structuresTyrosine kinase c-MetCABOSUN trialPosterior abdominal wallTumor diameter