2022
Association of autoimmune comorbidities with lichen planus: A United States-based case-control study in the All of Us research program
Fan R, Leasure AC, Cohen JM. Association of autoimmune comorbidities with lichen planus: A United States-based case-control study in the All of Us research program. Journal Of The American Academy Of Dermatology 2022, 87: 1451-1453. PMID: 35931217, DOI: 10.1016/j.jaad.2022.07.037.Peer-Reviewed Original ResearchAnalysis of Clinical Traits Associated With Cardiovascular Health, Genomic Profiles, and Neuroimaging Markers of Brain Health in Adults Without Stroke or Dementia
Acosta JN, Both CP, Rivier C, Szejko N, Leasure AC, Gill TM, Payabvash S, Sheth KN, Falcone GJ. Analysis of Clinical Traits Associated With Cardiovascular Health, Genomic Profiles, and Neuroimaging Markers of Brain Health in Adults Without Stroke or Dementia. JAMA Network Open 2022, 5: e2215328. PMID: 35622359, PMCID: PMC9142873, DOI: 10.1001/jamanetworkopen.2022.15328.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkersBrainCohort StudiesDementiaFemaleGenomicsHumansMaleNeuroimagingRisk FactorsStrokeUnited StatesConceptsBrain healthBrain volumeMagnetic resonance imagingLower mean volumeLifestyle factorsCardiovascular healthLarge population-based cohort studyLife's Simple 7 (LS7) scoresPopulation-based cohort studyBrain magnetic resonance imagingMean volumeWhite matter hyperintensity volumeBrain health benefitsCommunity-dwelling personsImproved brain healthOutcomes of interestUK BiobankFinal analytical sampleAsymptomatic personsCohort studyLS7 scoreNeuroimaging markerHyperintensity volumeMAIN OUTCOMEGenetic predispositionPrevalence of eczema among adults in the United States: a cross-sectional study in the All of Us research program
Leasure AC, Cohen JM. Prevalence of eczema among adults in the United States: a cross-sectional study in the All of Us research program. Archives Of Dermatological Research 2022, 315: 999-1001. PMID: 35147780, DOI: 10.1007/s00403-022-02328-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCross-Sectional StudiesEczemaEthnicityFemaleHumansMaleMiddle AgedPopulation HealthPrevalenceUnited StatesConceptsPrevalence of eczemaEczema casesEczema prevalenceConfidence intervalsCross-sectional studyEHR dataAvailable EHR dataCross-sectional analysisRace/ethnicityFemale predominanceSignificant morbidityUS adultsAge 75Average ageEczemaUs Research ProgramAdult cohortHispanic participantsPrevalenceAge 18US studiesAgeWhite participantsAdultsParticipants
2021
Prevalence of lichen planus in the United States: A cross-sectional study of the All of Us research program
Leasure AC, Cohen JM. Prevalence of lichen planus in the United States: A cross-sectional study of the All of Us research program. Journal Of The American Academy Of Dermatology 2021, 87: 686-687. PMID: 34920026, DOI: 10.1016/j.jaad.2021.12.013.Peer-Reviewed Original ResearchCardiovascular Health Disparities in Racial and Other Underrepresented Groups: Initial Results From the All of Us Research Program
Acosta JN, Leasure AC, Both CP, Szejko N, Brown S, Torres‐Lopez V, Abdelhakim S, Schindler J, Petersen N, Sansing L, Gill TM, Sheth KN, Falcone GJ. Cardiovascular Health Disparities in Racial and Other Underrepresented Groups: Initial Results From the All of Us Research Program. Journal Of The American Heart Association 2021, 10: e021724. PMID: 34431358, PMCID: PMC8649271, DOI: 10.1161/jaha.121.021724.Peer-Reviewed Original ResearchPrevalence of granuloma annulare in the United States: a cross‐sectional study in the All of Us Research Program
Leasure AC, Damsky W, Cohen JM. Prevalence of granuloma annulare in the United States: a cross‐sectional study in the All of Us Research Program. International Journal Of Dermatology 2021, 61: e301-e302. PMID: 34363612, PMCID: PMC8818807, DOI: 10.1111/ijd.15832.Peer-Reviewed Original ResearchIntracerebral Hemorrhage in Patients With COVID-19
Leasure AC, Khan YM, Iyer R, Elkind MSV, Sansing LH, Falcone GJ, Sheth KN. Intracerebral Hemorrhage in Patients With COVID-19. Stroke 2021, 52: e321-e323. PMID: 34082576, PMCID: PMC8238884, DOI: 10.1161/strokeaha.121.034215.Peer-Reviewed Original ResearchAdolescentAdultAge FactorsAgedAnticoagulantsCerebral HemorrhageCOVID-19C-Reactive ProteinExtracorporeal Membrane OxygenationFemaleHeart Disease Risk FactorsHospital MortalityHospitalizationHumansIntensive Care UnitsInterleukin-6MaleMiddle AgedRegistriesRespiration, ArtificialRisk FactorsSARS-CoV-2Sex FactorsUnited StatesYoung Adult
2018
Minority Patients are Less Likely to Undergo Withdrawal of Care After Spontaneous Intracerebral Hemorrhage
Ormseth CH, Falcone GJ, Jasak SD, Mampre DM, Leasure AC, Miyares LC, Hwang DY, James ML, Testai FD, Becker KJ, Tirschwell DL, Langefeld CD, Woo D, Sheth KN. Minority Patients are Less Likely to Undergo Withdrawal of Care After Spontaneous Intracerebral Hemorrhage. Neurocritical Care 2018, 29: 419-425. PMID: 29949003, PMCID: PMC6286261, DOI: 10.1007/s12028-018-0554-4.Peer-Reviewed Original ResearchConceptsIntracerebral hemorrhageHematoma volumeAdmission Glasgow Coma ScaleEthnic/Racial VariationsNon-traumatic intracerebral hemorrhageIntracerebral Hemorrhage (ERICH) studyProspective cohort studyGlasgow Coma ScaleIntensive care unitWithdrawal of careSpontaneous intracerebral hemorrhageSimilar mortality ratesLogistic regression analysisRace/ethnicity modifiesRace/ethnicityCMO patientsHospital mortalityCohort studyRankin ScaleWhite patientsComa ScaleBlack patientsCare unitEndotracheal intubationICH patients
2017
Oral Anticoagulation and Functional Outcome after Intracerebral Hemorrhage
Biffi A, Kuramatsu JB, Leasure A, Kamel H, Kourkoulis C, Schwab K, Ayres AM, Elm J, Gurol ME, Greenberg SM, Viswanathan A, Anderson CD, Schwab S, Rosand J, Testai FD, Woo D, Huttner HB, Sheth KN. Oral Anticoagulation and Functional Outcome after Intracerebral Hemorrhage. Annals Of Neurology 2017, 82: 755-765. PMID: 29028130, PMCID: PMC5730065, DOI: 10.1002/ana.25079.Peer-Reviewed Original ResearchConceptsFavorable functional outcomeFunctional outcomeICH survivorsStroke incidenceEthnic/Racial VariationsIntracerebral Hemorrhage (ERICH) studyLong-term outcomesCox regression modelIndividual patient dataAnn NeurolLobar hemorrhageLobar ICHTreatment resumptionOral anticoagulationHematoma locationICH locationIntracerebral hemorrhageTherapeutic dilemmaICH studiesICH casesMultivariate analysisPropensity scorePatient dataRacial variationMortality