2022
Immune cellular components and signaling pathways in the tumor microenvironment.
Yenyuwadee S, Aliazis K, Wang Q, Christofides A, Shah R, Patsoukis N, Boussiotis VA. Immune cellular components and signaling pathways in the tumor microenvironment. Seminars In Cancer Biology 2022, 86: 187-201. PMID: 35985559, DOI: 10.1016/j.semcancer.2022.08.004.Peer-Reviewed Original ResearchThe complex role of tumor-infiltrating macrophages.
Christofides A, Strauss L, Yeo A, Cao C, Charest A, Boussiotis VA. The complex role of tumor-infiltrating macrophages. Nature Immunology 2022, 23: 1148-1156. PMID: 35879449, DOI: 10.1038/s41590-022-01267-2.Peer-Reviewed Original ResearchSingle-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progression.
Yeo AT, Rawal S, Delcuze B, Christofides A, Atayde A, Strauss L, Balaj L, Rogers VA, Uhlmann EJ, Varma H, Carter BS, Boussiotis VA, Charest A. Single-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progression. Nature Immunology 2022, 23: 971-984. PMID: 35624211, PMCID: PMC9174057, DOI: 10.1038/s41590-022-01215-0.Peer-Reviewed Original ResearchStructural, biochemical, and functional properties of the Rap1-Interacting Adaptor Molecule (RIAM).
Sari-Ak D, Torres-Gomez A, Yazicioglu YF, Christofides A, Patsoukis N, Lafuente EM, Boussiotis VA. Structural, biochemical, and functional properties of the Rap1-Interacting Adaptor Molecule (RIAM). Biomedical Journal 2022, 45: 289-298. PMID: 34601137, PMCID: PMC9250098, DOI: 10.1016/j.bj.2021.09.005.Peer-Reviewed Original Research
2021
Flow Cytometric Analysis for Identification of the Innate and Adaptive Immune Cells of Murine Lung.
Christofides A, Cao C, Pal R, Aksoylar HI, Boussiotis VA. Flow Cytometric Analysis for Identification of the Innate and Adaptive Immune Cells of Murine Lung. Journal Of Visualized Experiments : JoVE 2021 PMID: 34866628, DOI: 10.3791/62985.Peer-Reviewed Original ResearchThe role of peroxisome proliferator-activated receptors (PPAR) in immune responses.
Christofides A, Konstantinidou E, Jani C, Boussiotis VA. The role of peroxisome proliferator-activated receptors (PPAR) in immune responses. Metabolism: Clinical And Experimental 2021, 114: 154338. PMID: 32791172, PMCID: PMC7736084, DOI: 10.1016/j.metabol.2020.154338.Peer-Reviewed Original ResearchCommentary on: Combination of Metabolic Intervention and T Cell Therapy Enhances Solid Tumor Immunotherapy.
Christofides A, Tijaro-Ovalle NM, Boussiotis VA. Commentary on: Combination of Metabolic Intervention and T Cell Therapy Enhances Solid Tumor Immunotherapy. Immunometabolism 2021, 3 PMID: 33927895, PMCID: PMC8081294, DOI: 10.20900/immunometab20210016.Peer-Reviewed Original Research
2020
Targeted deletion of PD-1 in myeloid cells induces antitumor immunity.
Strauss L, Mahmoud MAA, Weaver JD, Tijaro-Ovalle NM, Christofides A, Wang Q, Pal R, Yuan M, Asara J, Patsoukis N, Boussiotis VA. Targeted deletion of PD-1 in myeloid cells induces antitumor immunity. Science Immunology 2020, 5 PMID: 31901074, PMCID: PMC7183328, DOI: 10.1126/sciimmunol.aay1863.Peer-Reviewed Original Research
2018
Critical Role of IL-8 Targeting in Gliomas.
Kosmopoulos M, Christofides A, Drekolias D, Zavras PD, Gargalionis AN, Piperi C. Critical Role of IL-8 Targeting in Gliomas. Current Medicinal Chemistry 2018, 25: 1954-1967. PMID: 29189120, DOI: 10.2174/0929867325666171129125712.Peer-Reviewed Original Research
2016
Epigenetic regulation of cancer biology and anti-tumor immunity by EZH2.
Christofides A, Karantanos T, Bardhan K, Boussiotis VA. Epigenetic regulation of cancer biology and anti-tumor immunity by EZH2. Oncotarget 2016, 7: 85624-85640. PMID: 27793053, PMCID: PMC5356764, DOI: 10.18632/oncotarget.12928.Peer-Reviewed Original ResearchCorrigendum: Regulation of T Cell Differentiation and Function by EZH2.
Karantanos T, Christofides A, Bardhan K, Li L, Boussiotis VA. Corrigendum: Regulation of T Cell Differentiation and Function by EZH2. Frontiers In Immunology 2016, 7: 346. PMID: 27648006, PMCID: PMC5022364, DOI: 10.3389/fimmu.2016.00346.Peer-Reviewed Original Research
2015
Pathophysiological mechanisms regulated by cytokines in gliomas.
Christofides A, Kosmopoulos M, Piperi C. Pathophysiological mechanisms regulated by cytokines in gliomas. Cytokine 2015, 71: 377-84. PMID: 25458967, DOI: 10.1016/j.cyto.2014.09.008.Peer-Reviewed Original Research
2013
Osteoprotegerin expression during the micro- and macrometastatic phases of the osteoblastic metastasis in prostate cancer: therapeutic implications.
Pneumaticos SG, Christofides A, Gkioka E, Kalogeropoulos T, Msaouel P, Koutsilieris M. Osteoprotegerin expression during the micro- and macrometastatic phases of the osteoblastic metastasis in prostate cancer: therapeutic implications. Expert Opinion On Therapeutic Targets 2013, 17: 1395-403. PMID: 24024908, DOI: 10.1517/14728222.2013.834889.Peer-Reviewed Original Research