2020
High concordance between chart review adjudication and electronic medical record data to identify prevalent and incident diabetes mellitus among persons with and without HIV
McGinnis KA, Justice AC, Bailin S, Wellons M, Freiberg M, Koethe JR. High concordance between chart review adjudication and electronic medical record data to identify prevalent and incident diabetes mellitus among persons with and without HIV. Pharmacoepidemiology And Drug Safety 2020, 29: 1432-1439. PMID: 33006179, PMCID: PMC7810212, DOI: 10.1002/pds.5111.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationElectronic medical recordsChart reviewVeterans Aging Cohort Study Biomarker CohortElectronic medical record dataPhysician chart reviewHIV-negative participantsIncident diabetes mellitusICD-9 codesMedical record dataIndication of diabetesPhysician adjudicationIncident diabetesDiabetes mellitusHIV infectionBiomarker cohortHIV statusDiabetes prevalenceMedical recordsMedication recordsLaboratory valuesEpidemiologic studiesDiabetes diagnosisDiagnostic criteriaDiabetesValidation for using electronic health records to identify community acquired pneumonia hospitalization among people with and without HIV
Rodriguez-Barradas MC, McGinnis KA, Akgün K, Tate JP, Brown ST, Butt AA, Fine M, Goetz MB, Graber CJ, Huang L, Rimland D, Justice A, Crothers K. Validation for using electronic health records to identify community acquired pneumonia hospitalization among people with and without HIV. Pneumonia 2020, 12: 6. PMID: 32724760, PMCID: PMC7382068, DOI: 10.1186/s41479-020-00068-1.Peer-Reviewed Original ResearchICD-9 codesPharmacy dataUninfected groupEHR algorithmPrimary positionOverall positive predictive valueResultsFive hundred fortyGroup of patientsElectronic health record dataICD-9 diagnosisHealth record dataPositive predictive valueCode-based algorithmsElectronic health recordsCAP hospitalizationsCOPD exacerbationsMicrobiologic workupOverall PPVUninfected patientsAspiration pneumoniaPneumonia hospitalizationsHospital admissionHIV statusCaP diagnosisEtiologic diagnosis
2019
343. T-cell Subsets Associated with Diabetes in Veterans with and without HIV
Bailin S, McGinnis K, McDonnell W, So-Armah K, Wellons M, Doyle M, Mallal S, Justice A, Freiberg M, Koethe J. 343. T-cell Subsets Associated with Diabetes in Veterans with and without HIV. Open Forum Infectious Diseases 2019, 6: s182-s183. PMCID: PMC6810455, DOI: 10.1093/ofid/ofz360.416.Peer-Reviewed Original ResearchVeterans Aging Cohort StudyT cell subsetsPrevalent diabetesT cellsHIV statusMemory CD4Immune activationNaïve CD8VA electronic medical recordsMultivariate logistic regression modelAdaptive immune activationAdaptive immune profileT effector memoryChronic immune activationEffector memory cellsAging Cohort StudyCentral memory cellsMemory T cellsBody mass indexICD-9 codesPeripheral mononuclear cellsUnhealthy alcohol useElectronic medical recordsLogistic regression modelsRace/ethnicity
2018
Accuracy of electronic health record data for the diagnosis of chronic obstructive pulmonary disease in persons living with HIV and uninfected persons
Crothers K, Rodriguez CV, Nance RM, Akgun K, Shahrir S, Kim J, Hoo G, Sharafkhaneh A, Crane HM, Justice AC. Accuracy of electronic health record data for the diagnosis of chronic obstructive pulmonary disease in persons living with HIV and uninfected persons. Pharmacoepidemiology And Drug Safety 2018, 28: 140-147. PMID: 29923258, PMCID: PMC6309326, DOI: 10.1002/pds.4567.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, InhalationAge FactorsAlgorithmsBronchodilator AgentsCohort StudiesData AccuracyData Interpretation, StatisticalDrug PrescriptionsElectronic Health RecordsFemaleHIV InfectionsHumansInternational Classification of DiseasesLogistic ModelsMaleMiddle AgedNebulizers and VaporizersPrevalencePulmonary Disease, Chronic ObstructiveRisk FactorsSmokingSpirometryConceptsChronic obstructive pulmonary diseaseICD-9 codesObstructive pulmonary diseaseElectronic health record dataHealth record dataPulmonary diseaseHIV-Associated Lung Emphysema (EXHALE) studyIntegrated Clinical Systems cohortVeterans Aging Cohort StudyHIV uninfected personsAIDS Research NetworkAging Cohort StudyRecord dataEHR dataReceiver-operating curveCohort studyRespiratory symptomsHIV statusUninfected personsClinical variablesDevelopment cohortClinical indicationsSpirometry dataSpirometryUninfected individuals
2012
Receipt of Opioid Analgesics by HIV-Infected and Uninfected Patients
Edelman EJ, Gordon K, Becker WC, Goulet JL, Skanderson M, Gaither JR, Brennan Braden J, Gordon AJ, Kerns RD, Justice AC, Fiellin DA. Receipt of Opioid Analgesics by HIV-Infected and Uninfected Patients. Journal Of General Internal Medicine 2012, 28: 82-90. PMID: 22895747, PMCID: PMC3539026, DOI: 10.1007/s11606-012-2189-z.Peer-Reviewed Original ResearchConceptsLong-term opioidsHigh-dose opioidsUninfected patientsOpioid receiptHIV statusPain diagnosisHIV infectionVeterans Aging Cohort StudyVeterans Health Administration (VHA) careDaily morphine equivalent doseAcute pain diagnosisDays of opioidsMorphine equivalent doseAging Cohort StudyDesignCross-sectional analysisChronic pain diagnosesICD-9 codesVulnerable patient populationAverage daily doseMorphine equivalentsOpioid prescriptionsCohort studyDaily doseOpioid analgesicsPain management
2008
Measuring Quality of Care in Syncope: Case Definition Affects Reported Electrocardiogram Use but Does Not Bias Reporting
Schuur JD, Justice A. Measuring Quality of Care in Syncope: Case Definition Affects Reported Electrocardiogram Use but Does Not Bias Reporting. Academic Emergency Medicine 2008, 16: 40-49. PMID: 19145713, PMCID: PMC3157750, DOI: 10.1111/j.1553-2712.2008.00303.x.Peer-Reviewed Original ResearchConceptsICD-9 codesCase definitionECG useEmergency departmentHospital characteristicsICD-9 diagnosis codesModerate agreementICD-9 diagnosisMultivariate logistic regressionNational quality measuresQuality of careED portionPatient ageED patientsFemale patientsDischarge diagnosisDiagnosis codesSyncope patientsECG rateElectrocardiogram useOnly moderate agreementPatientsSyncopeECG utilizationLogistic regression
2006
Increased COPD Among HIV-Positive Compared to HIV-Negative Veterans
Crothers K, Butt AA, Gibert CL, Rodriguez-Barradas MC, Crystal S, Justice AC, Team F. Increased COPD Among HIV-Positive Compared to HIV-Negative Veterans. CHEST Journal 2006, 130: 1326-1333. PMID: 17099007, DOI: 10.1378/chest.130.5.1326.Peer-Reviewed Original ResearchConceptsInjection drug usePrevalence of COPDHIV-negative subjectsIndependent risk factorHIV infectionICD-9 codesRisk factorsDiagnostic codesAlcohol abuseICD-9 diagnostic codesHIV-negative veteransActive antiretroviral therapyHIV-positive patientsEra of HAARTHIV-negative menHIV-positive subjectsProspective observational studyPathogenesis of COPDRisk of COPDHealth care providersElectronic medical recordsRace/ethnicityAntiretroviral therapyHIV-positiveCigarette smokingMedical Disease and Alcohol Use Among Veterans With Human Immunodeficiency Infection
Justice AC, Lasky E, McGinnis KA, Skanderson M, Conigliaro J, Fultz SL, Crothers K, Rabeneck L, Rodriguez-Barradas M, Weissman SB, Bryant K. Medical Disease and Alcohol Use Among Veterans With Human Immunodeficiency Infection. Medical Care 2006, 44: s52-s60. PMID: 16849969, DOI: 10.1097/01.mlr.0000228003.08925.8c.Peer-Reviewed Original ResearchConceptsICD-9 diagnostic codesICD-9 codesChart reviewMedical diseasesDiagnostic codesAlcohol useHepatitis CLevel of exposureHIV infectionAlcohol exposureMultivariate modelGreater exposure levelsCD4 cell countHIV-positive patientsIntravenous drug useObstructive lung diseaseHuman immunodeficiency infectionCurrent alcohol useNonlinearity of associationsDiagnosis of abuseCohort studyBacterial pneumoniaPast drinkersViral loadLung diseaseRates and predictors of hepatitis C virus treatment in HCV–HIV‐coinfected subjects
BUTT AA, JUSTICE AC, SKANDERSON M, GOOD C, KWOH CK. Rates and predictors of hepatitis C virus treatment in HCV–HIV‐coinfected subjects. Alimentary Pharmacology & Therapeutics 2006, 24: 585-591. PMID: 16907891, DOI: 10.1111/j.1365-2036.2006.03020.x.Peer-Reviewed Original ResearchConceptsHepatitis C virus (HCV) treatmentC virus treatmentHepatitis C virusHepatitis C virus-infected subjectsHCV-HIVVirus-infected subjectsC virusVirus treatmentTreatment ratesVeterans Affairs National Patient Care DatabaseDrug useNational Patient Care DatabaseImpact of comorbiditiesEffect of comorbidityPatient Care DatabaseICD-9 codesCoinfected subjectsHispanic racePharmacy dataBlack raceCare databaseMajor depressionPsychiatric illnessMild depressionBipolar disorder