2011
Prognostic Value of the SYNTAX Score in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention Analysis From the ACUITY (Acute Catheterization and Urgent Intervention Triage StrategY) Trial
Palmerini T, Genereux P, Caixeta A, Cristea E, Lansky A, Mehran R, Dangas G, Lazar D, Sanchez R, Fahy M, Xu K, Stone GW. Prognostic Value of the SYNTAX Score in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention Analysis From the ACUITY (Acute Catheterization and Urgent Intervention Triage StrategY) Trial. Journal Of The American College Of Cardiology 2011, 57: 2389-2397. PMID: 21658558, DOI: 10.1016/j.jacc.2011.02.032.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAngioplasty, Balloon, CoronaryCardiac CatheterizationCoronary AngiographyCoronary Artery BypassElectrocardiographyEmergency TreatmentFemaleHeparin, Low-Molecular-WeightHirudinsHospital MortalityHumansItalyKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisPeptide FragmentsPrognosisProportional Hazards ModelsProspective StudiesRecombinant ProteinsRisk AssessmentROC CurveSeverity of Illness IndexStatistics, NonparametricSurvival AnalysisTreatment OutcomeTriageConceptsSegment elevation acute coronary syndromesElevation acute coronary syndromePercutaneous coronary interventionAcute coronary syndromeSYNTAX scoreCoronary syndromeCardiac deathACUITY trialIndependent predictorsPredictive valueTarget vessel revascularization rateStable ischemic heart diseaseTriple-vessel coronary diseaseVessel revascularization rateCardiac mortality rateMyocardial infarction ratePre-specified subgroupsRisk-stratify patientsIschemic heart diseaseAngiographic substudySS tertilesInfarction rateRevascularization ratesCoronary interventionCoronary disease
2009
Impact of Myocardial Bridge on Clinical Outcome After Coronary Stent Placement
Tsujita K, Maehara A, Mintz GS, Doi H, Kubo T, Castellanos C, Liu J, Yang J, Oviedo C, Franklin-Bond T, Sugirtharaj DD, Dangas GD, Lansky AJ, Stone GW, Moses JW, Leon MB, Mehran R. Impact of Myocardial Bridge on Clinical Outcome After Coronary Stent Placement. The American Journal Of Cardiology 2009, 103: 1344-1348. PMID: 19427426, DOI: 10.1016/j.amjcard.2009.01.340.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationCoronary stent placementStent placementMyocardial bridgeArtery lesionsObstructive lesionsClinical outcomesStent groupTarget lesion revascularization rateStent group patientsTarget vessel revascularizationComposite end pointCoronary artery lesionsMinimum stent areaGroup patientsRevascularization ratesConsecutive patientsLeft anteriorObstructive diseaseSystolic compressionCoronary arterySignificant plaqueStent areaStent restenosisIntravascular ultrasound
2008
Comparison of Angiographic and Intravascular Ultrasonic Detection of Myocardial Bridging of the Left Anterior Descending Coronary Artery
Tsujita K, Maehara A, Mintz GS, Doi H, Kubo T, Castellanos C, Liu J, Yang J, Oviedo C, Franklin-Bond T, Dasgupta N, Biro S, Dani L, Dangas GD, Mehran R, Kirtane AJ, Lansky AJ, Kreps EM, Collins MB, Stone GW, Moses JW, Leon MB. Comparison of Angiographic and Intravascular Ultrasonic Detection of Myocardial Bridging of the Left Anterior Descending Coronary Artery. The American Journal Of Cardiology 2008, 102: 1608-1613. PMID: 19064013, DOI: 10.1016/j.amjcard.2008.07.054.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary AngiographyCoronary Artery DiseaseCoronary VesselsFemaleHumansMaleMiddle AgedMyocardial BridgingStatistics, NonparametricUltrasonography, InterventionalConceptsMyocardial bridgingIntravascular ultrasoundCoronary arterySystolic compressionLow left ventricular ejection fractionDe novo coronary lesionsLeft ventricular ejection fractionComparison of AngiographicDistal reference segmentsMaximum plaque burdenNovo coronary lesionsVentricular ejection fractionUseful anatomic informationConsecutive patientsEjection fractionLeft anteriorClinical featuresCoronary lesionsPlaque burdenProximal stenosisIntimal thicknessStudy populationPatientsAccurate diagnosisArtery
2005
Intravascular Ultrasound Study of Patterns of Calcium in Ruptured Coronary Plaques
Fujii K, Carlier SG, Mintz GS, Takebayashi H, Yasuda T, Costa RA, Moussa I, Dangas G, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB. Intravascular Ultrasound Study of Patterns of Calcium in Ruptured Coronary Plaques. The American Journal Of Cardiology 2005, 96: 352-357. PMID: 16054456, DOI: 10.1016/j.amjcard.2005.03.074.Peer-Reviewed Original ResearchMeSH KeywordsAgedCalcinosisChi-Square DistributionCoronary Artery DiseaseFemaleHumansLogistic ModelsMaleMiddle AgedRuptureStatistics, NonparametricUltrasonography, InterventionalConceptsRuptured plaquesControl plaquesCalcium depositsCoronary calciumSuperficial calciumLarge calcium depositsLumen cross-sectional areaMinimum lumen cross-sectional areaRuptured coronary plaquesIntravascular ultrasound studyArc of calciumAtherosclerotic plaque developmentDeep calciumCoronary plaquesSmall calcium depositsPlaque instabilityPlaque ruptureUltrasound studyPlaque developmentPlaquesCross-sectional areaLess calciumCalciumLong segmentGroupImpact and Determinants of Left Ventricular Function in Patients Undergoing Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction
Halkin A, Stone GW, Dixon SR, Grines CL, Tcheng JE, Cox DA, Garcia E, Brodie B, Stuckey TD, Mehran R, Lansky AJ. Impact and Determinants of Left Ventricular Function in Patients Undergoing Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction. The American Journal Of Cardiology 2005, 96: 325-331. PMID: 16054451, DOI: 10.1016/j.amjcard.2005.03.069.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionLeft ventricular functionBaseline left ventricular functionPrimary angioplastyBaseline LVEFVentricular functionIndependent predictorsIndex procedureMyocardial infarctionInfarct zone regional wall motionBaseline left ventricular dysfunctionMyocardial Infarction grade 0Primary percutaneous coronary interventionOne-year survival ratePrevious acute myocardial infarctionMultivessel coronary diseaseLeft ventricular dysfunctionPercutaneous coronary interventionVentricular ejection fractionStrong independent predictorRegional wall motionCADILLAC trialPreprocedural ThrombolysisVentricular dysfunctionCoronary interventionSirolimus-Eluting versus Bare Nitinol Stent for Obstructive Superficial Femoral Artery Disease: The SIROCCO II Trial
Duda SH, Bosiers M, Lammer J, Scheinert D, Zeller T, Tielbeek A, Anderson J, Wiesinger B, Tepe G, Lansky A, Mudde C, Tielemans H, Bérégi JP. Sirolimus-Eluting versus Bare Nitinol Stent for Obstructive Superficial Femoral Artery Disease: The SIROCCO II Trial. Journal Of Vascular And Interventional Radiology 2005, 16: 331-338. PMID: 15758128, DOI: 10.1097/01.rvi.0000151260.74519.ca.Peer-Reviewed Original ResearchConceptsSirolimus-eluting stent groupStent groupBare stent groupMean lumen diameterSignificant differencesLumen diameterSuperficial femoral artery diseaseSuperficial femoral artery obstructionChronic limb ischemiaFemoral artery diseaseFemoral artery obstructionAnkle-brachial indexBinary restenosis rateDouble-blind studySymptoms of claudicationBare nitinol stentsSirolimus-eluting stentsStandard interventional techniquesArtery obstructionPrimary endpointII trialAdverse eventsAngiographic outcomesArtery diseaseLimb ischemiaCreatine kinase-MB enzyme elevation and long-term clinical events after successful coronary stenting in lesions with ruptured plaque
Fujii K, Carlier SG, Mintz GS, Kobayashi Y, Jacoboff D, Nierenberg H, Takebayashi H, Yasuda T, Moussa I, Dangas G, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Leon MB, Moses JW. Creatine kinase-MB enzyme elevation and long-term clinical events after successful coronary stenting in lesions with ruptured plaque. The American Journal Of Cardiology 2005, 95: 355-359. PMID: 15670544, DOI: 10.1016/j.amjcard.2004.09.033.Peer-Reviewed Original ResearchMeSH KeywordsAnalysis of VarianceCase-Control StudiesChi-Square DistributionCineangiographyCoronary AngiographyCoronary Artery DiseaseCreatine KinaseCreatine Kinase, MB FormFemaleHumansImage Processing, Computer-AssistedIsoenzymesMaleMiddle AgedRuptureStatistics, NonparametricStentsUltrasonography, InterventionalConceptsAcute coronary syndromeCoronary syndromeCoronary stentingClinical outcomesStent implantationRuptured plaquesCreatine kinase-MB isoenzyme releaseCreatine kinase‐MB enzyme elevationLong-term clinical eventsCK-MB elevationCK-MB releaseSuccessful coronary stentingControl patientsUnstable anginaEnzyme elevationIndependent predictorsProcedural complicationsClinical eventsPlaque ruptureIntravascular ultrasoundPatientsLong-term eventsPlaquesComposite rateSyndrome
2004
Impact of chronic kidney disease on prognosis of patients with diabetes mellitus treated with percutaneous coronary intervention
Nikolsky E, Mehran R, Turcot D, Aymong ED, Mintz GS, Lasic Z, Lansky AJ, Tsounias E, Moses JW, Stone GW, Leon MB, Dangas GD. Impact of chronic kidney disease on prognosis of patients with diabetes mellitus treated with percutaneous coronary intervention. The American Journal Of Cardiology 2004, 94: 300-305. PMID: 15276092, DOI: 10.1016/j.amjcard.2004.04.023.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAngioplasty, Balloon, CoronaryCause of DeathChi-Square DistributionCohort StudiesCoronary DiseaseDiabetic AngiopathiesFemaleHumansKidney Failure, ChronicMaleMiddle AgedProbabilityPrognosisRenal DialysisRisk AssessmentSeverity of Illness IndexSex FactorsStatistics, NonparametricStentsSurvival AnalysisTreatment OutcomeConceptsChronic kidney diseasePercutaneous coronary interventionContrast-induced nephropathyPrognosis of patientsCoronary interventionRenal functionDiabetes mellitusKidney diseaseMortality rateImpact of CKDRole of CKDDe novo dialysisOutcomes of patientsHospital complicationsGastrointestinal bleedingNeurologic eventsFrequent complicationDiabetic patientsIndependent predictorsInsulin treatmentPatientsContrast mediumNephropathyDialysisMellitus
2003
Safety and efficacy of a novel device for treatment of thrombotic and atherosclerotic lesions in native coronary arteries and saphenous vein grafts: Results from the multicenter X‐sizer for treatment of thrombus and atherosclerosis in coronary applications trial (X‐TRACT) study
Stone GW, Cox DA, Low R, Cates CU, Satler L, Bailey SR, Kuntz RE, Lansky AJ. Safety and efficacy of a novel device for treatment of thrombotic and atherosclerotic lesions in native coronary arteries and saphenous vein grafts: Results from the multicenter X‐sizer for treatment of thrombus and atherosclerosis in coronary applications trial (X‐TRACT) study. Catheterization And Cardiovascular Interventions 2003, 58: 419-427. PMID: 12652487, DOI: 10.1002/ccd.10511.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryAtherectomy, CoronaryChi-Square DistributionCoronary AngiographyCoronary Artery DiseaseCoronary ThrombosisEquipment DesignEquipment SafetyFemaleFollow-Up StudiesGraft Occlusion, VascularHumansMaleMiddle AgedProbabilityRisk AssessmentSaphenous VeinStatistics, NonparametricStentsThrombectomyTreatment OutcomeConceptsSaphenous vein graftsNative coronary arteriesVein graftsX-SizerThrombotic lesionsCoronary arteryNon-Q-wave MIDistal branch occlusionTIMI 3 flowSide branch occlusionTreatment of thrombusDistal thromboemboliPeriprocedural MITIMI 0Adverse eventsThromboembolic complicationsConsecutive patientsAntegrade flowBranch occlusionPercutaneous interventionHistorical controlsAtherosclerotic lesionsTrial studyU.S. CentersLesions
2002
New-Device Angioplasty in Women: Clinical Outcome and Predictors in a 7,372-Patient Registry
Lansky AJ, Mehran R, Dangas G, Desai K, Costantini-Ortiz C, Cristea E, New G, Negoita M, Stone GW, Leon MB. New-Device Angioplasty in Women: Clinical Outcome and Predictors in a 7,372-Patient Registry. Epidemiology 2002, 13: s46-s51. PMID: 12071484, DOI: 10.1097/00001648-200205001-00010.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsNew device angioplastyClinical outcomesFemale genderHospital mortalityLate mortalityIndependent predictorsMortality rateHospital major adverse cardiac eventsIschemic coronary artery diseaseLong-term clinical outcomesSaphenous vein graft lesionsMultivariable logistic regression analysisDevice-specific outcomesHospital cardiac mortalityLate clinical outcomesAdverse cardiac eventsComorbid risk factorsCongestive heart failureNative coronary arteriesOutcomes of womenVein graft lesionsCoronary artery diseaseReference vessel sizeConventional balloon angioplasty