2016
Diagnostic Accuracy of Fast Computational Approaches to Derive Fractional Flow Reserve From Diagnostic Coronary Angiography The International Multicenter FAVOR Pilot Study
Tu S, Westra J, Yang J, von Birgelen C, Ferrara A, Pellicano M, Nef H, Tebaldi M, Murasato Y, Lansky A, Barbato E, van der Heijden LC, Reiber JH, Holm NR, Wijns W, Group F. Diagnostic Accuracy of Fast Computational Approaches to Derive Fractional Flow Reserve From Diagnostic Coronary Angiography The International Multicenter FAVOR Pilot Study. JACC Cardiovascular Interventions 2016, 9: 2024-2035. PMID: 27712739, DOI: 10.1016/j.jcin.2016.07.013.Peer-Reviewed Original ResearchMeSH KeywordsAdenosineAdministration, IntravenousAgedArea Under CurveBlood Flow VelocityCardiac CatheterizationChinaComputer SimulationCoronary AngiographyCoronary StenosisCoronary VesselsEuropeFeasibility StudiesFemaleFractional Flow Reserve, MyocardialHumansHyperemiaJapanMaleMiddle AgedModels, CardiovascularMyocardial Perfusion ImagingPilot ProjectsPredictive Value of TestsPrognosisProspective StudiesRadiographic Image Interpretation, Computer-AssistedRegional Blood FlowReproducibility of ResultsROC CurveSeverity of Illness IndexTime FactorsUnited StatesVasodilator AgentsWorkflowConceptsQuantitative flow ratioHyperemic flow velocityReceiver-operating characteristic curveCoronary angiographyDiagnostic accuracyAngiographic percent diameter stenosisDiagnostic coronary angiographyProspective multicenter studyIndependent core laboratoryAdenosine-induced hyperemiaPercent diameter stenosisQuantitative coronary angiographyIntermediate coronary lesionsCharacteristic curveFractional flow reservePositive likelihood ratioOverall diagnostic accuracyNegative likelihood ratioDrug-induced hyperemiaLikelihood ratioCoronary lesionsMulticenter studyDiameter stenosisMaximal hyperemiaFlow reserve
2013
A Blood-Based Gene Expression Test for Obstructive Coronary Artery Disease Tested in Symptomatic Nondiabetic Patients Referred for Myocardial Perfusion Imaging The COMPASS Study
Thomas GS, Voros S, McPherson JA, Lansky AJ, Winn ME, Bateman TM, Elashoff MR, Lieu HD, Johnson AM, Daniels SE, Ladapo JA, Phelps CE, Douglas PS, Rosenberg S. A Blood-Based Gene Expression Test for Obstructive Coronary Artery Disease Tested in Symptomatic Nondiabetic Patients Referred for Myocardial Perfusion Imaging The COMPASS Study. Circulation Genomic And Precision Medicine 2013, 6: 154-162. PMID: 23418288, DOI: 10.1161/circgenetics.112.964015.Peer-Reviewed Original ResearchConceptsMyocardial perfusion imagingInvasive coronary angiographyGene expression scoreCoronary angiographyNegative predictive valueNondiabetic patientsSymptomatic patientsClinical factorsPredictive valuePrespecified primary end pointObstructive coronary artery diseaseAbnormal myocardial perfusion imagingBlood-based gene expression testAdverse cardiovascular eventsPrimary end pointCoronary artery diseaseReceiver-operating characteristic curvePeripheral blood samplesReceiver-operating characteristic analysisCoronary artery disease diagnosisMaximum percent stenosisGene expression testReceiver-operating characteristicCardiovascular eventsArtery disease