2002
Randomized Trial of 90Sr/90Y β-Radiation Versus Placebo Control for Treatment of In-Stent Restenosis
Popma JJ, Suntharalingam M, Lansky AJ, Heuser RR, Speiser B, Teirstein PS, Massullo V, Bass T, Henderson R, Silber S, von Rottkay P, Bonan R, Ho KK, Osattin, MPH A, Kuntz RE. Randomized Trial of 90Sr/90Y β-Radiation Versus Placebo Control for Treatment of In-Stent Restenosis. Circulation 2002, 106: 1090-1096. PMID: 12196334, DOI: 10.1161/01.cir.0000027814.96651.72.Peer-Reviewed Original ResearchConceptsTarget vessel revascularizationStent restenosisPlacebo-treated patientsPrimary end pointCatheter-based treatmentIn-Stent RestenosisPlacebo sourcesStent thrombosesAngiographic restenosisClinical restenosisFirst multicenterIntracoronary radiationMyocardial infarctionPlacebo controlPatientsPrescribed doseRestenosisConventional treatmentIntracoronary catheterEnd pointDay 244PlaceboRevascularizationTreatmentIncidence
1999
Quantitative angiographic analysis of stent restenosis in the scripps coronary radiation to inhibit intimal proliferation post stenting (SCRIPPS) trial
Lansky A, Popma J, Massullo V, Jani S, Russo R, Schatz R, Steuterman S, Guarneri E, Wu H, Mehran R, Mintz G, Leon M, Teirstein P. Quantitative angiographic analysis of stent restenosis in the scripps coronary radiation to inhibit intimal proliferation post stenting (SCRIPPS) trial. The American Journal Of Cardiology 1999, 84: 410-414. PMID: 10468078, DOI: 10.1016/s0002-9149(99)00325-2.Peer-Reviewed Original ResearchConceptsStent marginsStenting TrialStent restenosisIr-192Quantitative angiographic resultsQuantitative angiographic analysisLower restenosis ratePercent diameter stenosisLower relative riskPlacebo sourcesAngiographic resultsRestenosis rateDiameter stenosisAngiographic analysisRelative riskRestenosisTreatment lengthIridium-192Successful interventionsTrialsFurther studiesPatientsTreatmentStenosisFollow