2013
Low-dose of oral factor Xa inhibitors in patients with a recent acute coronary syndrome: A systematic review and meta-analysis of randomized trials
Obonska K, Navarese EP, Lansky A, Tarantini G, Rossini R, Kozinski M, Musumeci G, Di Pasquale G, Górny B, Szczesniak A, Kowalewski M, Gurbel PA, Kubica J. Low-dose of oral factor Xa inhibitors in patients with a recent acute coronary syndrome: A systematic review and meta-analysis of randomized trials. Atherosclerosis 2013, 229: 482-488. PMID: 23672879, DOI: 10.1016/j.atherosclerosis.2013.04.022.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeRecent acute coronary syndromeOral factor Xa inhibitorsMajor bleeding complicationsNew oral anticoagulantsFactor Xa inhibitorsBleeding complicationsMajor bleedingCoronary syndromeOral anticoagulantsStandard therapyMyocardial infarctionOdds ratioXa inhibitorsSetting of ACSSystematic reviewAnti-Xa groupIntracranial bleeding ratesRecurrent MI ratesSecondary efficacy endpointsNew myocardial infarctionFactor X inhibitorsDose-related increaseEfficacy endpointPrimary endpoint
2004
A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention Development and initial validation
Mehran R, Aymong E, Nikolsky E, Lasic Z, Iakovou I, Fahy M, Mintz G, Lansky A, Moses J, Stone G, Leon M, Dangas G. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention Development and initial validation. Journal Of The American College Of Cardiology 2004, 44: 1393-1399. PMID: 15464318, DOI: 10.1016/j.jacc.2004.06.068.Peer-Reviewed Original ResearchConceptsContrast-induced nephropathyPercutaneous coronary interventionSimple risk scoreRisk scoreRate of CINRisk of CINCandidate univariate predictorsMultivariate logistic regressionTotal risk scoreGood discriminative powerWeighted integerCoronary interventionIndependent predictorsUnivariate predictorsRisk factorsOdds ratioProcedural characteristicsCumulative riskPatientsLogistic regressionIntervention developmentOverall occurrenceInvestigational purposesNephropathyScores