2005
Intravascular Ultrasound Study of Patterns of Calcium in Ruptured Coronary Plaques
Fujii K, Carlier SG, Mintz GS, Takebayashi H, Yasuda T, Costa RA, Moussa I, Dangas G, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB. Intravascular Ultrasound Study of Patterns of Calcium in Ruptured Coronary Plaques. The American Journal Of Cardiology 2005, 96: 352-357. PMID: 16054456, DOI: 10.1016/j.amjcard.2005.03.074.Peer-Reviewed Original ResearchConceptsRuptured plaquesControl plaquesCalcium depositsCoronary calciumSuperficial calciumLarge calcium depositsLumen cross-sectional areaMinimum lumen cross-sectional areaRuptured coronary plaquesIntravascular ultrasound studyArc of calciumAtherosclerotic plaque developmentDeep calciumCoronary plaquesSmall calcium depositsPlaque instabilityPlaque ruptureUltrasound studyPlaque developmentPlaquesCross-sectional areaLess calciumCalciumLong segmentGroup
2003
Increased CK-MB release is a “trade-off” for optimal stent implantation an intravascular ultrasound study
Iakovou I, Mintz GS, Dangas G, Abizaid A, Mehran R, Kobayashi Y, Lansky AJ, Aymong ED, Nikolsky E, Stone GW, Moses JW, Leon MB. Increased CK-MB release is a “trade-off” for optimal stent implantation an intravascular ultrasound study. Journal Of The American College Of Cardiology 2003, 42: 1900-1905. PMID: 14662249, DOI: 10.1016/j.jacc.2003.06.012.Peer-Reviewed Original ResearchConceptsCK-MB releaseTarget lesion revascularizationOptimal stent implantationStent expansionLesion revascularizationClinical restenosisStent implantationGroup 1Creatine kinase-MB isoenzyme releaseGroup 3Lower mortalityIntravascular ultrasound-guided stentingLower target lesion revascularizationPeak CK-MB valuesMajor adverse cardiac eventsLumen cross-sectional areaAdverse cardiac eventsAggressive stent expansionPercutaneous coronary interventionIntravascular ultrasound studyCK-MB valuesLate mortalityCardiac eventsCoronary interventionConsecutive patientsCorrelation of coronary arterial remodeling determined by intravascular ultrasound with angiographic diameter reduction of 20% to 60%
Hirose M, Kobayashi Y, Mintz GS, Moussa I, Mehran R, Lansky AJ, Dangas G, Kreps EM, Collins MB, Stone GW, Colombo A, Leon MB, Moses JW. Correlation of coronary arterial remodeling determined by intravascular ultrasound with angiographic diameter reduction of 20% to 60%. The American Journal Of Cardiology 2003, 92: 141-145. PMID: 12860214, DOI: 10.1016/s0002-9149(03)00528-9.Peer-Reviewed Original ResearchConceptsEEM cross-sectional areaNegative remodelingIntermediate remodelingPositive remodelingIntermediate stenosisCoronary lesionsCross-sectional areaDistal referenceIntravascular ultrasoundExternal elastic membrane cross-sectional areaLumen cross-sectional areaPreintervention intravascular ultrasoundStenotic coronary lesionsNative coronary lesionsCoronary arterial remodelingCoronary stenosisArterial remodelingProximal referenceLess plaqueArea stenosisStenosisLesionsLesion formationHard plaquesRemodeling occurs
2001
Serial intravascular ultrasound analysis of edge recurrence after intracoronary gamma radiation treatment of native artery in-stent restenosis lesions
Ahmed J, Mintz G, Waksman R, Lansky A, Mehran R, Wu H, Weissman N, Pichard A, Satler L, Kent K, Leon M. Serial intravascular ultrasound analysis of edge recurrence after intracoronary gamma radiation treatment of native artery in-stent restenosis lesions. The American Journal Of Cardiology 2001, 87: 1145-1149. PMID: 11356387, DOI: 10.1016/s0002-9149(01)01483-7.Peer-Reviewed Original ResearchConceptsLumen cross-sectional areaIntimal hyperplasia cross-sectional areaSerial intravascular ultrasound analysisMedia cross-sectional areaEdge recurrenceIntravascular ultrasound analysisCross-sectional areaStent restenosisExternal elastic membrane cross-sectional areaUltrasound analysisStent restenosis TrialStent restenosis lesionsDistal cross-sectional areasGreater decreaseGreater increaseRestenosis lesionsRestenosis TrialPositive remodelingProximal plaqueWashington RadiationNative coronariesMean lumenNeointimal hyperplasiaRecurrenceLesions
2000
Comparison of debulking followed by stenting versus stenting alone for saphenous vein graft aortoostial lesions: immediate and one-year clinical outcomes
Ahmed J, Hong M, Mehran R, Mintz G, Lansky A, Pichard A, Satler L, Kent K, Wu H, Stone G, Leon M. Comparison of debulking followed by stenting versus stenting alone for saphenous vein graft aortoostial lesions: immediate and one-year clinical outcomes. Journal Of The American College Of Cardiology 2000, 35: 1560-1568. PMID: 10807461, DOI: 10.1016/s0735-1097(00)00592-1.Peer-Reviewed Original ResearchConceptsOne-year clinical outcomesLumen cross-sectional areaLate clinical outcomesClinical outcomesStent implantationProcedural successRestenotic lesionsIntravascular ultrasoundCross-sectional areaOverall cardiac event-free survivalCardiac event-free survivalLate cardiac eventsEvent-free survivalOverall procedural successCox regression analysisComplex lesion subsetsPalmaz-Schatz stentsLesion revascularizationCardiac eventsMost patientsConsecutive patientsIndependent predictorsProcedural complicationsLesion subsetsMyocardial infarction
1998
Remodeling after directional coronary atherectomy (with and without adjunct percutaneous transluminal coronary angioplasty): a serial angiographic and intravascular ultrasound analysis from the optimal atherectomy restenosis study
Lansky A, Mintz G, Popma J, Pichard A, Kent K, Satler L, Baim D, Kuntz R, Simonton C, Bersin R, Hinohara T, Fitzgerald P, Leon M. Remodeling after directional coronary atherectomy (with and without adjunct percutaneous transluminal coronary angioplasty): a serial angiographic and intravascular ultrasound analysis from the optimal atherectomy restenosis study. Journal Of The American College Of Cardiology 1998, 32: 329-337. PMID: 9708457, DOI: 10.1016/s0735-1097(98)00245-9.Peer-Reviewed Original ResearchMeSH KeywordsAnatomy, Cross-SectionalAngioplasty, Balloon, CoronaryAtherectomy, CoronaryCell DivisionCerebral AngiographyCineradiographyCombined Modality TherapyConstriction, PathologicCoronary Artery DiseaseCoronary VesselsElastic TissueFemaleFollow-Up StudiesHumansMaleMiddle AgedNitroglycerinRecurrenceTunica MediaUltrasonography, InterventionalVasodilator AgentsConceptsDirectional coronary atherectomyExternal elastic membraneMinimum lumen diameterLumen cross-sectional areaQuantitative coronary angiographyDiameter stenosisCoronary atherectomyCross-sectional areaReference segmentsLesion external elastic membraneOptimal directional coronary atherectomyEEM cross-sectional areaIntravascular ultrasound substudySerial IVUS studyIntravascular ultrasound analysisMajor side branchesMechanism of restenosisIntravascular ultrasound measurementsUltrasound substudyIntracoronary nitroglycerinCoronary angiographyRestenotic lesionsLate lumenArterial remodelingIVUS study