2021
An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group.
Kunadian V, Chieffo A, Camici PG, Berry C, Escaned J, Maas AHEM, Prescott E, Karam N, Appelman Y, Fraccaro C, Buchanan GL, Manzo-Silberman S, Al-Lamee R, Regar E, Lansky A, Abbott JD, Badimon L, Duncker DJ, Mehran R, Capodanno D, Baumbach A. An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group. EuroIntervention 2021, 16: 1049-1069. PMID: 32624456, PMCID: PMC9707543, DOI: 10.4244/eijy20m07_01.Peer-Reviewed Original ResearchConceptsNon-obstructive coronary arteriesConsensus documentCoronary arteryObstructive coronary artery diseaseCardiology Working GroupCoronary artery diseasePercutaneous Cardiovascular InterventionsInternational Study GroupExpert consensus documentQuality of lifeHealth care costsCoronary vasospasmINOCA patientsCardiovascular eventsMicrovascular dysfunctionAngina pectorisArtery diseaseHospital admissionCoronary pathophysiologyInvasive angiographyAsymptomatic individualsINOCAStudy groupClinical practiceCare costs
2020
An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group
Kunadian V, Chieffo A, Camici PG, Berry C, Escaned J, Maas AHEM, Prescott E, Karam N, Appelman Y, Fraccaro C, Buchanan G, Manzo-Silberman S, Al-Lamee R, Regar E, Lansky A, Abbott JD, Badimon L, Duncker DJ, Mehran R, Capodanno D, Baumbach A. An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group. European Heart Journal 2020, 41: 3504-3520. PMID: 32626906, PMCID: PMC7577516, DOI: 10.1093/eurheartj/ehaa503.Peer-Reviewed Original ResearchConceptsNon-obstructive coronary arteriesConsensus documentCoronary arteryObstructive coronary artery diseaseCardiology Working GroupCoronary artery diseasePercutaneous Cardiovascular InterventionsInternational Study GroupExpert consensus documentQuality of lifeHealth care costsCoronary vasospasmINOCA patientsCardiovascular eventsMicrovascular dysfunctionAngina pectorisArtery diseaseHospital admissionCoronary pathophysiologyInvasive angiographyAsymptomatic individualsINOCAStudy groupClinical practiceCare costs
2013
A composite peripheral blood gene expression score has high sensitivity for obstructive coronary artery disease in a non-invasive imaging population and correlates with plaque burden and morphology by
Voros S, Thomas G, Bateman T, Mcpherson J, Lansky A, Douglas P, Ladapo J, Wingrove J, Elashoff M, Rosenberg S. A composite peripheral blood gene expression score has high sensitivity for obstructive coronary artery disease in a non-invasive imaging population and correlates with plaque burden and morphology by. European Heart Journal 2013, 34: p2413. DOI: 10.1093/eurheartj/eht308.p2413.Peer-Reviewed Original ResearchMyocardial perfusion imagingNon-calcified plaquePlaque burdenInvasive angiogramObstructive coronary artery diseaseQuantitative CTA analysisNon-diabetic patientsCoronary artery diseaseOverall plaque burdenQuantitative coronary angiographyNegative predictive valueGene expression scoreNeutrophil upregulationArtery diseaseCalcium scoreCoronary angiographyInvasive angiographyGES scoresCAD casesBlood samplesCTA analysisPatientsPerfusion imagingReferral pathsPredictive value
2012
Usefulness of Noninvasive Fractional Flow Reserve Computed from Coronary Computed Tomographic Angiograms for Intermediate Stenoses Confirmed by Quantitative Coronary Angiography
Min JK, Koo BK, Erglis A, Doh JH, Daniels DV, Jegere S, Kim HS, Dunning AM, DeFrance T, Lansky A, Leipsic J. Usefulness of Noninvasive Fractional Flow Reserve Computed from Coronary Computed Tomographic Angiograms for Intermediate Stenoses Confirmed by Quantitative Coronary Angiography. The American Journal Of Cardiology 2012, 110: 971-976. PMID: 22749390, DOI: 10.1016/j.amjcard.2012.05.033.Peer-Reviewed Original ResearchConceptsLesion-specific ischemiaFractional flow reserveCoronary lesionsIntermediate stenosisFlow reservePredictive valueNoninvasive methodComputed Tomographic AngiogramsCoronary computed tomographyNoninvasive fractional flow reserveQuantitative coronary angiographyReceiver operator characteristic curveIntermediate stenosis severityNegative predictive valuePositive predictive valueOperator characteristic curveCoronary angiographyInvasive angiographyMean ageTomographic angiogramBland-Altman analysisStudy groupIschemiaComputed tomographyNovel noninvasive method
2011
Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients
Elashoff MR, Wingrove JA, Beineke P, Daniels SE, Tingley WG, Rosenberg S, Voros S, Kraus WE, Ginsburg GS, Schwartz RS, Ellis SG, Tahirkheli N, Waksman R, McPherson J, Lansky AJ, Topol EJ. Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients. BMC Medical Genomics 2011, 4: 26. PMID: 21443790, PMCID: PMC3072303, DOI: 10.1186/1755-8794-4-26.Peer-Reviewed Original ResearchConceptsObstructive coronary artery diseaseCoronary artery diseaseNon-diabetic patientsDiabetic statusArtery diseaseRT-PCR analysisNon-invasive blood testStudy of patientsPeripheral blood cellsClassifier genesCell type-specific markersPREDICT cohortGene expressionClinical factorsInvasive angiographyBlood testsControl cohortRegistry casesCohort analysisPREDICT studyResultsMicroarray analysisDiagnostic utilityPopulation predictorsRT-PCR dataCAD association