2005
Contrast-Induced nephropathy after percutaneous coronary interventions in relation to chronic kidney disease and hemodynamic variables
Dangas G, Iakovou I, Nikolsky E, Aymong ED, Mintz GS, Kipshidze NN, Lansky AJ, Moussa I, Stone GW, Moses JW, Leon MB, Mehran R. Contrast-Induced nephropathy after percutaneous coronary interventions in relation to chronic kidney disease and hemodynamic variables. The American Journal Of Cardiology 2005, 95: 13-19. PMID: 15619387, DOI: 10.1016/j.amjcard.2004.08.056.Peer-Reviewed Original ResearchConceptsContrast-induced nephropathyChronic kidney diseasePercutaneous coronary interventionIntra-aortic balloon pump useCoronary interventionKidney diseasePump usePredictors of CINPresence of CKDBaseline chronic kidney diseaseLower baseline hematocritBaseline renal functionContrast medium volumeHospital complicationsPeriprocedural hypotensionHospital stayBaseline characteristicsRenal functionConsecutive patientsEjection fractionBaseline hematocritPulmonary edemaHemodynamic variablesHemodynamic parametersPatients
2004
Impact of chronic kidney disease on prognosis of patients with diabetes mellitus treated with percutaneous coronary intervention
Nikolsky E, Mehran R, Turcot D, Aymong ED, Mintz GS, Lasic Z, Lansky AJ, Tsounias E, Moses JW, Stone GW, Leon MB, Dangas GD. Impact of chronic kidney disease on prognosis of patients with diabetes mellitus treated with percutaneous coronary intervention. The American Journal Of Cardiology 2004, 94: 300-305. PMID: 15276092, DOI: 10.1016/j.amjcard.2004.04.023.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAngioplasty, Balloon, CoronaryCause of DeathChi-Square DistributionCohort StudiesCoronary DiseaseDiabetic AngiopathiesFemaleHumansKidney Failure, ChronicMaleMiddle AgedProbabilityPrognosisRenal DialysisRisk AssessmentSeverity of Illness IndexSex FactorsStatistics, NonparametricStentsSurvival AnalysisTreatment OutcomeConceptsChronic kidney diseasePercutaneous coronary interventionContrast-induced nephropathyPrognosis of patientsCoronary interventionRenal functionDiabetes mellitusKidney diseaseMortality rateImpact of CKDRole of CKDDe novo dialysisOutcomes of patientsHospital complicationsGastrointestinal bleedingNeurologic eventsFrequent complicationDiabetic patientsIndependent predictorsInsulin treatmentPatientsContrast mediumNephropathyDialysisMellitusImpact of Symptomatic Peripheral Arterial Disease on 1-Year Mortality in Patients Undergoing Percutaneous Coronary Interventions
Nikolsky E, Mehran R, Mintz GS, Dangas GD, Lansky AJ, Aymong ED, Negoita M, Fahy M, Moussa I, Roubin GS, Moses JW, Stone GW, Leon MB. Impact of Symptomatic Peripheral Arterial Disease on 1-Year Mortality in Patients Undergoing Percutaneous Coronary Interventions. Journal Of Endovascular Therapy 2004, 11: 60-70. PMID: 14748627, DOI: 10.1177/152660280401100108.Peer-Reviewed Original ResearchConceptsSymptomatic peripheral arterial diseasePeripheral arterial diseasePercutaneous coronary interventionCoronary interventionArterial diseaseProcedural successTarget lesionsPresence of PADUrgent coronary artery bypassSmaller body surface areaMore target lesionsAtherosclerotic risk factorsChronic renal insufficiencyCoronary artery bypassFifth of patientsTransient ischemic attackHigh rateBody surface areaHigh mortality rateLower ratesFemoral hematomaHospital complicationsIschemic attackRe-PCIArtery bypassImpact of Symptomatic Peripheral Arterial Disease on 1-Year Mortality in Patients Undergoing Percutaneous Coronary Interventions
Nikolsky E, Mehran R, Mintz G, Dangas G, Lansky A, Aymong E, Negoita M, Fahy M, Moussa I, Roubin G, Moses J, Stone G, Leon M. Impact of Symptomatic Peripheral Arterial Disease on 1-Year Mortality in Patients Undergoing Percutaneous Coronary Interventions. Journal Of Endovascular Therapy 2004, 11: 60-70. DOI: 10.1583/1545-1550(2004)011<0060:iospad>2.0.co;2.Peer-Reviewed Original ResearchSymptomatic peripheral arterial diseasePeripheral arterial diseasePercutaneous coronary interventionCoronary interventionArterial diseaseProcedural successTarget lesionsPresence of PADUrgent coronary artery bypassSmaller body surface areaMore target lesionsAtherosclerotic risk factorsChronic renal insufficiencyCoronary artery bypassFifth of patientsTransient ischemic attackHigh rateBody surface areaHigh mortality rateLower ratesFemoral hematomaHospital complicationsIschemic attackRe-PCIArtery bypass
2001
Carotid Artery Stenting in Patients with High-Risk Anatomy for Carotid Endarterectomy
Dangas G, Laird J, Mehran R, Satler L, Lansky A, Mintz G, Monsein L, Laureno R, Leon M. Carotid Artery Stenting in Patients with High-Risk Anatomy for Carotid Endarterectomy. Journal Of Endovascular Therapy 2001, 8: 39-43. PMID: 11220467, DOI: 10.1177/152660280100800106.Peer-Reviewed Original ResearchConceptsCarotid artery stentingHigh-risk anatomyCarotid endarterectomyCarotid arteryContralateral carotid artery occlusionPrevious ipsilateral carotid endarterectomyEndovascular revascularization techniquesIndependent neurological evaluationIpsilateral carotid endarterectomyPercutaneous femoral artery accessTransient ischemic attackCarotid artery occlusionPrevious radiation therapyFemoral artery accessCommon carotid bifurcationHospital complicationsIschemic attackNonneurological causesMinor strokeArtery occlusionNeurological evaluationRevascularization techniquesArtery stentingConsecutive patientsNeurological eventsCarotid Artery Stenting in Patients With High-Risk Anatomy for Carotid Endarterectomy
Dangas G, Laird J, Mehran R, Satler L, Lansky A, Mintz G, Monsein L, Laureno R, Leon M. Carotid Artery Stenting in Patients With High-Risk Anatomy for Carotid Endarterectomy. Journal Of Endovascular Therapy 2001, 8: 39-43. DOI: 10.1583/1545-1550(2001)008<0039:casipw>2.0.co;2.Peer-Reviewed Original ResearchCarotid artery stentingHigh-risk anatomyCarotid endarterectomyCarotid arteryContralateral carotid artery occlusionPrevious ipsilateral carotid endarterectomyEndovascular revascularization techniquesIndependent neurological evaluationIpsilateral carotid endarterectomyPercutaneous femoral artery accessTransient ischemic attackCarotid artery occlusionPrevious radiation therapyFemoral artery accessCommon carotid bifurcationHospital complicationsIschemic attackNonneurological causesMinor strokeArtery occlusionNeurological evaluationRevascularization techniquesArtery stentingConsecutive patientsNeurological events
2000
Postprocedural Hypotension after Carotid Artery Stent Placement: Predictors and Short- and Long-term Clinical Outcomes
Dangas G, Laird JR, Satler LF, Mehran R, Mintz GS, Larrain G, Lansky AJ, Gruberg L, Parsons EM, Laureno R, Monsein LH, Leon MB. Postprocedural Hypotension after Carotid Artery Stent Placement: Predictors and Short- and Long-term Clinical Outcomes. Radiology 2000, 215: 677-83. PMID: 10831683, DOI: 10.1148/radiology.215.3.r00jn04677.Peer-Reviewed Original ResearchConceptsCarotid artery stent placementStent placementGroup 2Clinical outcomesGroup 1Long-term clinical outcomesBalloon-expandable stent placementEvidence of hypovolemiaMinor ipsilateral strokeTransient ischemic attackCarotid sinus stimulationSelf-expanding stent placementGreater total mortalityLong-term riskBalloon-expandable stentsHospital complicationsIpsilateral strokeIschemic attackPersistent hypotensionPostprocedural hypotensionNeurologic eventsMajor strokeSinus stimulationArterial pressureConsecutive patientsTreatment of In-Stent Restenosis With Excimer Laser Coronary Angioplasty Versus Rotational Atherectomy
Mehran R, Dangas G, Mintz G, Waksman R, Abizaid A, Satler L, Pichard A, Kent K, Lansky A, Stone G, Leon M. Treatment of In-Stent Restenosis With Excimer Laser Coronary Angioplasty Versus Rotational Atherectomy. Circulation 2000, 101: 2484-2489. PMID: 10831522, DOI: 10.1161/01.cir.101.21.2484.Peer-Reviewed Original ResearchConceptsExcimer laser coronary angioplastyVolumetric IVUS analysisRotational atherectomyQuantitative coronary angiographicClinical resultsCoronary angiographicIVUS analysisLumen enlargementSimilar long-term clinical outcomesTarget lesion revascularization rateLong-term clinical outcomesSignificant between-group differencesIntimal hyperplasia volumeLesion revascularization rateLaser coronary angioplastyTreatment of diffuseIn-Stent RestenosisSimilar clinical resultsBetween-group differencesIntravascular ultrasound measurementsAdjunct PTCADiffuse ISRHospital complicationsAngiographic successRevascularization ratesPrognostic value of cardiac troponin-I levels following catheter-based coronary interventions
Fuchs S, Kornowski R, Mehran R, Lansky A, Satler L, Pichard A, Kent K, Clark C, Stone G, Leon M. Prognostic value of cardiac troponin-I levels following catheter-based coronary interventions. The American Journal Of Cardiology 2000, 85: 1077-1082. PMID: 10781755, DOI: 10.1016/s0002-9149(00)00699-8.Peer-Reviewed Original ResearchConceptsCatheter-based coronary interventionsCK-MB levelsHospital complicationsCoronary interventionCreatine kinase-MB fraction levelsCardiac event-free survivalIntermediate-term clinical outcomesTn-I levelsEvent-free survivalIntermediate-term outcomesRisk of mortalityQ-wave infarctionLesion revascularizationConsecutive patientsCoronary angioplastyIndependent predictorsClinical outcomesPrognostic significancePrognostic valueCoronary arteryMyocardial infarctionPlasma levelsSaphenous veinNormal limitsGroup IIPercutaneous revascularization of the internal mammary artery graft: short- and long-term outcomes
Gruberg L, Dangas G, Mehran R, Hong M, Waksman R, Mintz G, Kent K, Pichard A, Satler L, Lansky A, Stone G, Leon M. Percutaneous revascularization of the internal mammary artery graft: short- and long-term outcomes. Journal Of The American College Of Cardiology 2000, 35: 944-948. PMID: 10732892, DOI: 10.1016/s0735-1097(99)00652-x.Peer-Reviewed Original ResearchConceptsInternal mammary artery graftMammary artery graftsIMA graftsPercutaneous revascularizationBalloon angioplastyArtery graftClinical outcomesProcedural successMyocardial infarctionOne-year clinical outcomesLong-term clinical outcomesQ-wave myocardial infarctionAlternative interventional techniquesLower TLR rateUrgent bypass surgeryHigh procedural successLong-term outcomesTreatment of stenosisLong-term resultsOne-year ratesHospital complicationsHospital outcomesTLR rateAnastomotic lesionsBypass surgeryProcedural results and late clinical outcomes after percutaneous interventions using long (≥25 mm) versus short (<20 mm) stents
Kornowski R, Bhargava B, Fuchs D, Lansky A, Satler L, Pichard A, Hong M, Kent K, Mehran R, Stone G, Leon M. Procedural results and late clinical outcomes after percutaneous interventions using long (≥25 mm) versus short (<20 mm) stents. Journal Of The American College Of Cardiology 2000, 35: 612-618. PMID: 10716462, DOI: 10.1016/s0735-1097(99)00580-x.Peer-Reviewed Original ResearchConceptsShort stent groupsPeriprocedural non-Q-wave myocardial infarctionNon-Q-wave myocardial infarctionCardiac event-free survivalEvent-free survivalMyocardial infarctionClinical outcomesProcedural successStent groupShort stentsHospital complicationsLesion revascularizationLong stentsOverall cardiac event-free survivalLong-term clinical outcomesQ-wave myocardial infarctionLate clinical outcomesLong stent implantationsMajor procedural complicationsMean stent lengthMore diffuse lesionsSingle-vessel interventionVessel revascularization rateOverall procedural successLong-term outcomes
1999
Creatine Kinase-MB Enzyme Elevation Following Successful Saphenous Vein Graft Intervention Is Associated With Late Mortality
Hong M, Mehran R, Dangas G, Mintz G, Lansky A, Pichard A, Kent K, Satler L, Stone G, Leon M. Creatine Kinase-MB Enzyme Elevation Following Successful Saphenous Vein Graft Intervention Is Associated With Late Mortality. Circulation 1999, 100: 2400-2405. PMID: 10595951, DOI: 10.1161/01.cir.100.24.2400.Peer-Reviewed Original ResearchConceptsCK-MB elevationSaphenous vein graft interventionCK-MB riseVein graft interventionLate mortalityGraft interventionClinical eventsCreatine kinase‐MB enzyme elevationPeriprocedural CK-MB elevationNormal CK-MBMajor clinical eventsLate clinical eventsCreatine kinase elevationStrong independent predictorHospital complicationsSVG angioplastySVG interventionSVG lesionsConsecutive patientsDiabetes mellitusEnzyme elevationIndependent predictorsPrognostic significanceCK-MBMultivariate analysis
1998
Final Results of the Balloon vs Optimal Atherectomy Trial (BOAT)
Baim D, Cutlip D, Sharma S, Ho K, Fortuna R, Schreiber T, Feldman R, Shani J, Senerchia C, Zhang Y, Lansky A, Popma J, Kuntz R. Final Results of the Balloon vs Optimal Atherectomy Trial (BOAT). Circulation 1998, 97: 322-331. PMID: 9468205, DOI: 10.1161/01.cir.97.4.322.Peer-Reviewed Original ResearchConceptsAngiographic restenosisBalloon angioplastyHigh short-term successPrespecified primary end pointLower angiographic restenosisNative vessel lesionsSingle de novoPrimary end pointTarget vessel failureTarget vessel revascularizationResidual diameter stenosisLate clinical eventsConventional balloon angioplastyCreatine kinase-MBLow residual stenosisSignificant reductionHospital complicationsResidual stenosisLesion successMajor complicationsAngiographic restudyDiameter stenosisVessel lesionsClinical eventsLong-term benefits
1996
Angiographic and Clinical Outcome after Cutting Balloon Angioplasty.
Popma J, Lansky A, Purkayastha D, Hall L, Bonan R. Angiographic and Clinical Outcome after Cutting Balloon Angioplasty. Journal Of Invasive Cardiology 1996, 8 Suppl A: 12a-19a. PMID: 10785760.Peer-Reviewed Original ResearchBalloon angioplastyConventional balloon angioplastyResidual stenosisClinical outcomesBalloon useDiameter stenosisArtery ratioNon-complex coronary artery diseaseComplex coronary artery diseaseCutting Balloon AngioplastyReference artery sizeCoronary artery diseaseMinimal lumen diameterCore laboratory analysisPrevention of restenosisAngiographic core laboratory analysisNew device angioplastyHospital complicationsOstial locationAngiographic successArtery diseaseConsecutive patientsArtery sizeSignificant inverse relationshipMorphologic findings