2011
A Prospective Natural-History Study of Coronary Atherosclerosis
Stone GW, Maehara A, Lansky AJ, de Bruyne B, Cristea E, Mintz GS, Mehran R, McPherson J, Farhat N, Marso SP, Parise H, Templin B, White R, Zhang Z, Serruys PW. A Prospective Natural-History Study of Coronary Atherosclerosis. New England Journal Of Medicine 2011, 364: 226-235. PMID: 21247313, DOI: 10.1056/nejmoa1002358.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAngioplasty, Balloon, CoronaryCoronary AngiographyCoronary Artery DiseaseCoronary VesselsDisease ProgressionFemaleHumansKaplan-Meier EstimateMaleMiddle AgedPatient ReadmissionProportional Hazards ModelsProspective StudiesRecurrenceRisk FactorsUltrasonography, InterventionalConceptsMajor adverse cardiovascular eventsAdverse cardiovascular eventsAcute coronary syndromeNonculprit lesionsPercutaneous coronary interventionThin-cap fibroatheromaCardiovascular eventsCoronary syndromeCulprit lesionCoronary interventionPlaque burdenIntravascular ultrasonographyLuminal areaSubsequent major adverse cardiovascular eventsLesion-related risk factorsMild coronary artery stenosisProspective natural history studyLarger plaque burdenCoronary artery stenosisMinimal luminal areaNatural history studiesRecurrent eventsSmall luminal areaMedian followCoronary atherosclerosis
2008
Effectiveness of Drug-Eluting Stent Implantation for Patients With Unprotected Left Main Coronary Artery Stenosis
Kim YH, Dangas GD, Solinas E, Aoki J, Parise H, Kimura M, Franklin-Bond T, Dasgupta NK, Kirtane AJ, Moussa I, Lansky AJ, Collins M, Stone GW, Leon MB, Moses JW, Mehran R. Effectiveness of Drug-Eluting Stent Implantation for Patients With Unprotected Left Main Coronary Artery Stenosis. The American Journal Of Cardiology 2008, 101: 801-806. PMID: 18328844, DOI: 10.1016/j.amjcard.2007.10.052.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBlood Vessel Prosthesis ImplantationCoated Materials, BiocompatibleCoronary AngiographyCoronary StenosisElectrocardiographyFemaleFollow-Up StudiesHumansImmunosuppressive AgentsMaleMyocardial RevascularizationPaclitaxelProspective StudiesSirolimusStentsTreatment OutcomeTubulin ModulatorsUltrasonography, InterventionalConceptsHigh surgical riskMain coronary artery stenosisMajor adverse cardiac eventsUnprotected LMCA stenosisAdverse cardiac eventsCoronary artery stenosisSurgical riskLMCA stenosisCardiac eventsArtery stenosisStent thrombosisMyocardial infarctionBifurcation stenosisUnprotected left main coronary artery stenosisLeft main coronary artery stenosisDrug-eluting stent placementUrgent percutaneous coronary interventionQ-wave myocardial infarctionFeasible therapeutic alternativeOutcomes of patientsPercutaneous coronary interventionPaclitaxel-eluting stentsSingle-stent strategyUnfavorable clinical outcomeSirolimus-eluting stents
2007
Assessing intermediate left main coronary lesions using intravascular ultrasound
Sano K, Mintz GS, Carlier SG, de Ribamar Costa J, Qian J, Missel E, Shan S, Franklin-Bond T, Boland P, Weisz G, Moussa I, Dangas GD, Mehran R, Lansky AJ, Kreps EM, Collins MB, Stone GW, Leon MB, Moses JW. Assessing intermediate left main coronary lesions using intravascular ultrasound. American Heart Journal 2007, 154: 983-988. PMID: 17967608, DOI: 10.1016/j.ahj.2007.07.001.Peer-Reviewed Original ResearchConceptsLeft main coronary artery stenosisQuantitative coronary angiographySignificant left main coronary artery stenosisMinimal lumen areaIntravascular ultrasoundOstial lesionsIVUS analysisMain coronary artery stenosisLumen areaIVUS minimal lumen areaLeft main ostiumAmbiguous left main coronary artery stenosisCoronary artery stenosisMain coronary lesionsMinimal lumen diameterIVUS evaluationConsecutive patientsCoronary angiographyCoronary lesionsSuch patientsArtery stenosisPlaque burdenDiameter stenosisMain ostiumPhysiologic assessmentPercutaneous Coronary Revascularization Using a Trilayer Metal Phosphorylcholine-Coated Zotarolimus-Eluting Stent
Abizaid A, Lansky AJ, Fitzgerald PJ, Tanajura LF, Feres F, Staico R, Mattos L, Abizaid A, Chaves A, Centemero M, Sousa AG, Sousa JE, Zaugg MJ, Schwartz LB. Percutaneous Coronary Revascularization Using a Trilayer Metal Phosphorylcholine-Coated Zotarolimus-Eluting Stent. The American Journal Of Cardiology 2007, 99: 1403-1408. PMID: 17493469, DOI: 10.1016/j.amjcard.2006.12.064.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryBlood Vessel Prosthesis ImplantationCardiovascular AgentsCoronary AngiographyCoronary CirculationCoronary RestenosisCoronary StenosisFemaleFollow-Up StudiesHumansMaleMiddle AgedPhosphorylcholineProspective StudiesProsthesis DesignResearch DesignSirolimusStentsTreatment OutcomeTunica IntimaUltrasonography, InterventionalConceptsCoronary artery stenosisQuantitative coronary angiographyZoMaxx stentCoronary angiographyArtery stenosisDe novo coronary artery stenosisSingle-arm prospective clinical trialDevice-deployment success ratesMajor adverse cardiac eventsSegment late lumen lossCoronary occlusive diseaseIntravascular ultrasound resultsNeointimal volume obstructionAdverse cardiac eventsIndependent core laboratoryLate lumen lossNative coronary arteriesPercutaneous coronary revascularizationProspective clinical trialsCoronary stent systemReduction of restenosisCoronary revascularizationVolume obstructionCardiac eventsObstructive lesions
2006
Serial Angiographic Follow-Up of Sirolimus-Eluting Stents for Unprotected Left Main Coronary Artery Revascularization
Price MJ, Cristea E, Sawhney N, Kao JA, Moses JW, Leon MB, Costa RA, Lansky AJ, Teirstein PS. Serial Angiographic Follow-Up of Sirolimus-Eluting Stents for Unprotected Left Main Coronary Artery Revascularization. Journal Of The American College Of Cardiology 2006, 47: 871-877. PMID: 16487858, DOI: 10.1016/j.jacc.2005.12.015.Peer-Reviewed Original ResearchConceptsLate lossParent vesselUnprotected left main coronary artery stenosisLeft main coronary artery stenosisFinal minimal luminal diameterMain coronary artery revascularizationMain coronary artery stenosisSirolimus-eluting stent implantationEfficacy of SESCoronary artery revascularizationAngiographic Follow-upSirolimus-Eluting StentsCoronary artery stenosisMinimal luminal diameterArtery revascularizationCircumflex ostiumLesion restenosisLesion revascularizationLMCA diseaseLMCA interventionLMCA lesionsSES implantationAngiographic outcomesIndependent predictorsArtery stenosis
2002
Comparison of clinical outcomes using stents versus no stents after percutaneous coronary intervention for proximal left anterior descending versus proximal right and left circumflex coronary arteries
Ashby DT, Dangas G, Mehran R, Lansky AJ, Narasimaiah R, Iakovou I, Polena S, Satler LF, Pichard AD, Kent KM, Stone GW, Leon MB. Comparison of clinical outcomes using stents versus no stents after percutaneous coronary intervention for proximal left anterior descending versus proximal right and left circumflex coronary arteries. The American Journal Of Cardiology 2002, 89: 1162-1166. PMID: 12008168, DOI: 10.1016/s0002-9149(02)02297-x.Peer-Reviewed Original ResearchMeSH KeywordsAgedArteriesBlood Vessel Prosthesis ImplantationCohort StudiesCoronary Artery DiseaseCoronary RestenosisCoronary VesselsDistrict of ColumbiaFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative ComplicationsRadiographyStentsStroke VolumeSurvival AnalysisTime FactorsTreatment OutcomeConceptsPercutaneous coronary interventionTarget lesion revascularizationProximal LAD arteryProximal rightClinical restenosisCoronary interventionCircumflex arteryProcedural successLAD arteryProximal coronary artery stenosisSingle-vessel coronary diseaseAnterior descending (LAD) stenosisHigh rateCircumflex coronary arteryLower procedural successCoronary artery stenosisSignificant differencesDifferent lesion locationsCoronary artery stentsLesion revascularizationProximal LADCoronary diseaseArtery stenosisClinical outcomesHospital events
1999
Long-Term Follow-Up After Percutaneous Transluminal Coronary Angioplasty Was Not Performed Based on Intravascular Ultrasound Findings
Abizaid A, Mintz G, Mehran R, Abizaid A, Lansky A, Pichard A, Satler L, Wu H, Pappas C, Kent K, Leon M. Long-Term Follow-Up After Percutaneous Transluminal Coronary Angioplasty Was Not Performed Based on Intravascular Ultrasound Findings. Circulation 1999, 100: 256-261. PMID: 10411849, DOI: 10.1161/01.cir.100.3.256.Peer-Reviewed Original ResearchConceptsMinimum lumen areaIntravascular ultrasound findingsOnly independent predictorLumen areaIVUS minimum lumen areaEvent ratesDiabetes mellitusIndependent predictorsUltrasound findingsIVUS parametersArea stenosisLumen diameterPercutaneous transluminal coronary angioplastyLesion lumen areaNative artery lesionsTarget lesion revascularizationTransluminal coronary angioplastyCoronary artery stenosisMinimum lumen diameterLow event ratesArtery lesionsCardiac deathCoronary angioplastyArtery stenosisPlaque burden