2004
Prognostic utility of comparative methods for assessment of ST-segment resolution after primary angioplasty for acute myocardial infarction The controlled abciximab and device investigation to lower late angioplasty complications (CADILLAC) trial
McLaughlin M, Stone G, Aymong E, Gardner G, Mehran R, Lansky A, Grines C, Tcheng J, Cox D, Stuckey T, Garcia E, Guagliumi G, Turco M, Josephson M, Zimetbaum P. Prognostic utility of comparative methods for assessment of ST-segment resolution after primary angioplasty for acute myocardial infarction The controlled abciximab and device investigation to lower late angioplasty complications (CADILLAC) trial. Journal Of The American College Of Cardiology 2004, 44: 1215-1223. PMID: 15364322, DOI: 10.1016/j.jacc.2004.06.053.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryCoronary AngiographyCoronary CirculationElectrocardiographyFemaleHeart Conduction SystemHumansMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPostoperative ComplicationsPredictive Value of TestsPrognosisProspective StudiesRecurrenceRisk FactorsStatistics as TopicSurvival AnalysisTreatment OutcomeConceptsST-segment elevation resolutionPrimary percutaneous coronary interventionPrimary PCIST-segment elevationAcute myocardial infarctionLate Angioplasty Complications (CADILLAC) trialMaximum ST-segment elevationCombined end pointComplications TrialMyocardial infarctionBaseline ST-segment elevationEnd pointInfarct-related artery patencyHigh-risk categorizationPost-PCI electrocardiogramsST-segment resolutionPercutaneous coronary interventionTarget vessel patencyStrong independent predictorControlled AbciximabPrimary angioplastyArtery patencyCoronary interventionIndependent predictorsPrognostic utility
2000
Vascular remodeling and the local delivery of cytochalasin B after coronary angioplasty in humans
Lehmann K, Popma J, Werner J, Lansky A, Wilensky R. Vascular remodeling and the local delivery of cytochalasin B after coronary angioplasty in humans. Journal Of The American College Of Cardiology 2000, 35: 583-591. PMID: 10716458, DOI: 10.1016/s0735-1097(99)00603-8.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAngioplasty, Balloon, CoronaryCatheterization, PeripheralCoronary AngiographyCoronary DiseaseCoronary VesselsCytochalasin BDrug Delivery SystemsElectrocardiographyFeasibility StudiesFemaleHumansInfusions, Intra-ArterialMaleMiddle AgedMyocardial RevascularizationSafetyTreatment OutcomeConceptsCoronary angioplastyLocal deliveryVascular remodelingMinimal stenosis diameterSuccessful balloon angioplastyCombined end pointActive drug groupSuccessful coronary angioplastyLate lumen lossCytochalasin BSystemic drug administrationWarrants further studyInadequate dosingPlacebo groupClinical restenosisPharmacologic preventionAngioplasty siteClinical outcomesBalloon angioplastyLumen lossDrug groupsArterial constrictionElectrocardiographic variablesStenosis diameterAtherosclerotic plaquesRelation of coronary artery size to one-year clinical events after new device angioplasty of native coronary arteries (a New Approach to Coronary Intervention [NACI] Registry report)
Saucedo J, Popma J, Kennard E, Talley J, Lansky A, Leon M, Baim D, Investigators F. Relation of coronary artery size to one-year clinical events after new device angioplasty of native coronary arteries (a New Approach to Coronary Intervention [NACI] Registry report). The American Journal Of Cardiology 2000, 85: 166-171. PMID: 10955371, DOI: 10.1016/s0002-9149(99)00649-9.Peer-Reviewed Original ResearchConceptsReference vessel diameterNew device angioplastyNative coronary arteriesMinimal lumen diameterClinical eventsAngiographic outcomesCoronary arteryFinal minimal lumen diameterFinal percent diameter stenosisMajor adverse clinical eventsOne-year clinical eventsSmaller reference vessel diameterBaseline lesion characteristicsRisk of TLRCombined end pointAdverse clinical eventsCoronary artery diseaseCoronary Intervention RegistryEarly clinical eventsIncidence of deathSmall vesselsCoronary artery sizePercent diameter stenosisLesion revascularizationMultivessel disease
1999
Coronary Angioplasty with or without Stent Implantation for Acute Myocardial Infarction
Grines C, Cox D, Stone G, Garcia E, Mattos L, Giambartolomei A, Brodie B, Madonna O, Eijgelshoven M, Lansky A, O'Neill W, Morice M. Coronary Angioplasty with or without Stent Implantation for Acute Myocardial Infarction. New England Journal Of Medicine 1999, 341: 1949-1956. PMID: 10607811, DOI: 10.1056/nejm199912233412601.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionTarget vessel revascularizationAngioplasty groupStent groupMyocardial infarctionPrimary angioplastyCoronary angioplastyStent implantationMean minimal luminal diameterSix-month mortality rateEnd pointCombined end pointPrimary end pointPrimary coronary angioplastyCoronary stent implantationMinimal luminal diameterRoutine implantationClinical benefitMulticenter studyEmergency catheterizationLower incidenceLuminal diameterAngioplastyBlood flowMortality rate