2023
Variation in hospital use of cardiac resynchronization therapy-defibrillator among eligible patients and association with clinical outcomes
Chui P, Lan Z, Freeman J, Enriquez A, Khera R, Akar J, Masoudi F, Ong E, Curtis J. Variation in hospital use of cardiac resynchronization therapy-defibrillator among eligible patients and association with clinical outcomes. Heart Rhythm 2023, 20: 1000-1008. PMID: 36963741, DOI: 10.1016/j.hrthm.2023.03.022.Peer-Reviewed Original ResearchConceptsEligible patientsICD RegistryCardiac resynchronizationNational Cardiovascular Data Registry ICD RegistryCRT-D implantationCRT-D useHospital-level outcomesStrong guideline recommendationsHospital-level variationPatient-level outcomesIntraclass correlation coefficientQuality improvement effortsHospital mortalityGuideline indicationsReadmission ratesSelect patientsClinical outcomesGuideline recommendationsHospital variationHospital ratesUse of CRTHospital levelHospital usePatientsCase mix
2014
Clinical Impact of Atrial Fibrillation in Patients With the HeartMate II Left Ventricular Assist Device
Enriquez AD, Calenda B, Gandhi PU, Nair AP, Anyanwu AC, Pinney SP. Clinical Impact of Atrial Fibrillation in Patients With the HeartMate II Left Ventricular Assist Device. Journal Of The American College Of Cardiology 2014, 64: 1883-1890. PMID: 25444141, DOI: 10.1016/j.jacc.2014.07.989.Peer-Reviewed Original ResearchConceptsParoxysmal atrial fibrillationAtrial fibrillationHF hospitalizationThromboembolic eventsVentricular assist deviceHeartMate IIHMII LVADAssist deviceImpact of AFCox proportional hazards regressionEffect of AFKaplan-Meier survival analysisHigh INR levelsHeart failure hospitalizationMajor bleeding eventsPersistent atrial fibrillationProportional hazards regressionBleeding eventsHMII implantationINR levelsFailure hospitalizationPatient yearsComposite endpointIndependent predictorsClinical outcomesManagement of Hypertrophic Cardiomyopathy
Enriquez AD, Goldman ME. Management of Hypertrophic Cardiomyopathy. Annals Of Global Health 2014, 80: 35-45. PMID: 24751563, DOI: 10.1016/j.aogh.2013.12.004.Peer-Reviewed Original ResearchConceptsSudden cardiac deathHypertrophic cardiomyopathyHeart failureAtrial fibrillationHCM patientsManagement of HCMCommon genetic cardiovascular diseaseUnexplained myocardial hypertrophyAlcohol septal ablationOutflow tract obstructionRhythm control strategyPathophysiology of HCMRisk of thromboembolismMajority of patientsGeneral adult populationGenetic cardiovascular diseaseAutosomal dominant diseaseFamily membersSurgical myectomyRefractory symptomsRestrictive physiologySeptal ablationTract obstructionYounger patientsCardiac death
2013
The Role of Implantable Cardioverter-Defibrillators in Patients With Continuous Flow Left Ventricular Assist Devices
Enriquez AD, Calenda B, Miller MA, Anyanwu AC, Pinney SP. The Role of Implantable Cardioverter-Defibrillators in Patients With Continuous Flow Left Ventricular Assist Devices. Circulation Arrhythmia And Electrophysiology 2013, 6: 668-674. PMID: 23873139, DOI: 10.1161/circep.113.000457.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedArrhythmias, CardiacChi-Square DistributionDefibrillators, ImplantableElectric CountershockFemaleHeart FailureHeart TransplantationHeart-Assist DevicesHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisNew York CityProportional Hazards ModelsProsthesis DesignRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeVentricular Function, LeftWaiting ListsYoung AdultConceptsVentricular arrhythmiasActive ICDPost-LVAD ventricular arrhythmiasVentricular assist device supportAssist device supportContinuous-flow LVADHeartMate II LVADEnd of studyImplantable cardioverter defibrillatorVentricular assist deviceAppropriate shocksConsecutive patientsImproved survivalIschemic cardiomyopathySingle centerWorse prognosisMedian lengthMean agePatient populationCardioverter defibrillatorPatientsDevice supportAssist deviceICDLVAD