Mechanisms, Genetics, and Pathophysiology
Maestrelli P, Wisnewski A, Carlsten C, Munoz X, Tsui H, Vanoirbeek J, Malo J, Bernstein D. Mechanisms, Genetics, and Pathophysiology. 2021, 35-54. DOI: 10.1201/9781003000624-4.Peer-Reviewed Original ResearchOccupational asthmaAirway inflammationDevelopment of OASensitizer-induced occupational asthmaType of OAChemical respiratory allergyIgE-dependent hypersensitivityIrritant-induced asthmaIgE-mediated mechanismNeutrophilic airway inflammationIgE-mediated responsesWork-related symptomsPossible pathogenic mechanismsPathways of inflammationStimulation of cholinergicPathophysiology of diseaseHMW agentsInflammatory markersAirflow limitationBronchial hyperresponsivenessImmunologic sensitizationSensory nervesSensitized subjectsIgE antibodiesLMW agents