Tissue factor pathway inhibitors as a novel approach to antithrombotic therapy.
Sajadi S, Ezekowitz MD, Dhond A, Netrebko P. Tissue factor pathway inhibitors as a novel approach to antithrombotic therapy. Drug News & Perspectives 2003, 16: 363-9. PMID: 12973447, DOI: 10.1358/dnp.2003.16.6.829308.Peer-Reviewed Original ResearchConceptsTissue factor pathway inhibitorFactor pathway inhibitorTissue factorPathway inhibitorNew antithrombotic approachComplications of atherosclerosisPathogenesis of atherosclerosisAntithrombotic therapyAntithrombotic approachEndothelial injurySystemic hemostasisNeointimal formationVascular interventionsAtherosclerotic plaquesEndothelial cellsInhibitory effectExtrinsic pathwayAtherosclerosisInhibitorsPlaquesCoagulationEarly stagesComplicationsFactorsAnticoagulants