2024
Absence of Anti-Babesia microti antibody in commercial intravenous immunoglobulin (IVIG)
Kostka J, Maharjan A, Kumar S, Hackenyos D, Krause P, Dieckhaus K. Absence of Anti-Babesia microti antibody in commercial intravenous immunoglobulin (IVIG). PLOS Neglected Tropical Diseases 2024, 18: e0012035. PMID: 38484010, PMCID: PMC10965045, DOI: 10.1371/journal.pntd.0012035.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, ProtozoanBabesia microtiBabesiosisEnzyme-Linked Immunosorbent AssayHumansImmunoglobulins, IntravenousConceptsIntravenous immunoglobulinB. microti antibodiesBabesiosis patientsSpectrum of disease severityCommercial intravenous immunoglobulinEffective treatment strategiesSevere organ damageHost antibody responseImmunocompromised patientsAdjunctive therapyOrgan damageTreatment strategiesAcute andClinical trialsMicroti antibodiesAsymptomatic infectionAntibody responseTherapeutic benefitTherapeutic effectPatientsDisease severityAntibodiesImmunofluorescence assayProtozoan infectionsCommercial samples
2018
BmGPAC, an Antigen Capture Assay for Detection of Active Babesia microti Infection
Thekkiniath J, Mootien S, Lawres L, Perrin BA, Gewirtz M, Krause PJ, Williams S, Doggett J, Ledizet M, Mamoun C. BmGPAC, an Antigen Capture Assay for Detection of Active Babesia microti Infection. Journal Of Clinical Microbiology 2018, 56: 10.1128/jcm.00067-18. PMID: 30093394, PMCID: PMC6156295, DOI: 10.1128/jcm.00067-18.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, ProtozoanBabesia microtiBabesiosisCells, CulturedEnzyme-Linked Immunosorbent AssayErythrocytesFemaleHumansMaleMiceParasitologySerologic TestsConceptsHuman babesiosisBabesia microti infectionCapture enzyme-linked immunosorbent assayAntigen capture enzyme-linked immunosorbent assayAntigen capture assayEnzyme-linked immunosorbent assayZoonotic infectious diseaseAcute infectionBlood transfusionAsymptomatic infectionMicroti infectionReal-time PCRBlood supplyAnimal reservoir hostsDonor bloodEpidemiological surveyHuman patientsImmune systemSerological assaysImmunodominant antigensInfectionInfectious diseasesIntraerythrocytic protozoan parasitePatientsImmunosorbent assay
2016
Transfusion-transmitted babesiosis
Levin AE, Krause PJ. Transfusion-transmitted babesiosis. Current Opinion In Hematology 2016, 23: 573-580. PMID: 27537475, PMCID: PMC5241272, DOI: 10.1097/moh.0000000000000287.Peer-Reviewed Original ResearchConceptsTransfusion-transmitted babesiosisBlood donorsB. microti antibodiesInfectious blood donorsAssociated mortality rateOptimal screening strategyTransfusion-transmitted pathogensSignificant health burdenAvailable screening toolsUnited States populationPathogen inactivation methodsMicroti antibodiesSevere illnessHealth burdenMortality rateUS FoodDrug AdministrationBabesia microtiScreening toolLaboratory screeningScreening strategyBabesiosisInactivation methodPCR assaysRecent studies
2007
Serum Reactivity against Borrelia burgdorferi OspA in Patients with Rheumatoid Arthritis▿
Hsieh YF, Liu HW, Hsu TC, Wei J, Shih CM, Krause PJ, Tsay GJ. Serum Reactivity against Borrelia burgdorferi OspA in Patients with Rheumatoid Arthritis▿. MSphere 2007, 14: 1437-1441. PMID: 17881508, PMCID: PMC2168181, DOI: 10.1128/cvi.00151-07.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntibodies, BacterialAntigens, BacterialAntigens, SurfaceArthritis, RheumatoidAutoimmune DiseasesBacterial Outer Membrane ProteinsBacterial VaccinesBlotting, WesternBorrelia burgdorferiEnzyme-Linked Immunosorbent AssayFemaleHumansLipoproteinsLyme DiseaseMaleMiddle AgedRecombinant Fusion ProteinsConceptsRheumatoid arthritis patientsRheumatoid arthritisOspA antigenArthritis patientsAutoimmune diseasesSerum reactivityLyme diseaseDisease Activity ScoreCommon clinical featuresLyme disease patientsSurface protein AArthritis correlatesSynovial histologyOuter surface protein ALyme arthritisActivity scoreClinical featuresDisease patientsSerum concentrationsSimilar pathogenesisHealthy subjectsPatientsArthritisDisease severityDisease
2006
Confirmation of Tick Bite by Detection of Antibody to Ixodes Calreticulin Salivary Protein▿
Alarcon-Chaidez F, Ryan R, Wikel S, Dardick K, Lawler C, Foppa IM, Tomas P, Cushman A, Hsieh A, Spielman A, Bouchard KR, Dias F, Aslanzadeh J, Krause PJ. Confirmation of Tick Bite by Detection of Antibody to Ixodes Calreticulin Salivary Protein▿. MSphere 2006, 13: 1217-1222. PMID: 16928887, PMCID: PMC1656538, DOI: 10.1128/cvi.00201-06.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodiesBites and StingsCalreticulinEnzyme-Linked Immunosorbent AssayFemaleHumansIxodesMiceMice, Inbred BALB CMice, Inbred C3HModels, AnimalRecombinant ProteinsSalivary Proteins and PeptidesConceptsEnzyme-linked immunosorbent assayImmune responseTick exposureBALB/c miceC3H/HeNTick-borne infectionsHuman granulocytic anaplasmosisDetection of antibodiesLaboratory markersAntibody responseC miceTick biteSalivary proteinsObjective evidenceLyme diseaseImmunosorbent assayGranulocytic anaplasmosisHuman babesiosisSalivary glandsIxodes ticksAntibodiesBlood mealSame assayMiceSerum
2000
Serological Expression Cloning of Novel Immunoreactive Antigens of Babesia microti
Lodes M, Houghton R, Bruinsma E, Mohamath R, Reynolds L, Benson D, Krause P, Reed S, Persing D. Serological Expression Cloning of Novel Immunoreactive Antigens of Babesia microti. Infection And Immunity 2000, 68: 2783-2790. PMID: 10768973, PMCID: PMC97488, DOI: 10.1128/iai.68.5.2783-2790.2000.Peer-Reviewed Original ResearchConceptsRelated antigensBabesia microtiSerological expression cloningB. microtiHumoral immune responseB. microti infectionClass of antigensSporozoite surface antigenPatient serum poolsWestern blot analysisBlood transfusionMicroti infectionImmune responseSurface antigenImmunodominant antigensAntigenHuman babesiosisMolecular testsGenomic expression libraryPlasmodium spCausative agentSerum poolsImmunoreactive antigensBlot analysisMicroti
1992
Cytomegalovirus antibody detection in blood donors and mothers of very low birth weight neonates by using three serologic methods
Eisenfeld L, McLaughlin J, Mayo D, Klevjer-Anderson P, Silver H, Krause P, Anderson J, Herson V, Savidakis J, Lazar A, Rosenkrantz T, DeSilva H, Ryan R, group C, LeConche D, Donovan T, Ellis K, Buchanan D, Raye J, Pisciotto P, Rowe D, Knox I, Philipps A, Whiteley D, Apollonio J, Schick J, Conlon M. Cytomegalovirus antibody detection in blood donors and mothers of very low birth weight neonates by using three serologic methods. Diagnostic Microbiology And Infectious Disease 1992, 15: 125-128. PMID: 1315230, DOI: 10.1016/0732-8893(92)90035-r.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, ViralBlood DonorsCytomegalovirusCytomegalovirus InfectionsEnzyme-Linked Immunosorbent AssayFemaleFluorescent Antibody TechniqueHumansInfant, Low Birth WeightInfant, NewbornLatex Fixation TestsMaternal-Fetal ExchangePregnancyPregnancy Complications, InfectiousSensitivity and SpecificityConceptsEnzyme-linked immunosorbent assayLow birth weight neonatesBirth weight neonatesBlood donorsLatex agglutinationWeight neonatesAntibody detectionSerologic methodsCMV seroprevalence ratesHealthy blood donorsCMV screeningCMV serologyPremature infantsSeroprevalence ratesAntibody seroprevalenceImmunofluorescent antibodyIFA assayBlood populationsBorderline valuesImmunosorbent assayMaternal populationMothersNeonatesSerumDonors
1983
Unreliability of Rotazyme ELISA test in neonates
Krause P, Hyams J, Middleton P, Herson V, Flores J. Unreliability of Rotazyme ELISA test in neonates. The Journal Of Pediatrics 1983, 103: 259-262. PMID: 6308197, DOI: 10.1016/s0022-3476(83)80361-8.Commentaries, Editorials and Letters